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Jeremy Pratt

Observed names: J Pratt, J. Pratt
Institution: Sanofi (France)
OpenAlex ID: A5074656897
Riluzole Series. Synthesis and in Vivo “Antiglutamate” Activity of 6-Substituted-2-benzothiazolamines and 3-Substituted-2-imino-benzothiazolines
1999 · Patrick Jimonet, François Audiau, et al. · Journal of Medicinal Chemistry · 235
Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia
1992 · Jeremy Pratt, Jean Rataud, et al. · Neuroscience Letters · 149
Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents
1994 · Jean Rataud, Florence Debarnot, et al. · Neuroscience Letters · 115
The effect of riluzole on post-traumatic spinal cord injury in the rat
1996 · Jean-Marie Stutzmann, Jeremy Pratt, et al. · Neuroreport · 78
RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.
2001 · T Canton, G A Böhme, et al. · PubMed · 68
Glutamate uptake is decreased tardively in the spinal cord of FALS mice
1998 · Thierry Canton, Jeremy Pratt, et al. · Neuroreport · 65
Neuroprotective Profile of Enoxaparin, a Low Molecular Weight Heparin, in In Vivo Models of Cerebral Ischemia or Traumatic Brain Injury in Rats: a Review
2002 · Jean‐Marie Stutzmann, Veronique Mary, et al. · CNS Drug Reviews · 62
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RPR 119990, a Novel α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Antagonist: Synthesis, Pharmacological Properties, and Activity in an Animal Model of Amyotrophic Lateral Sclerosis
2001 · Thierry Canton, Georg Andrees Böhme, et al. · Journal of Pharmacology and Experimental Therapeutics · 46
Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn)
2000 · Philippe Kennel, Frederic Revah, et al. · Journal of the Neurological Sciences · 36
9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic Acid (RPR117824): Selective Anticonvulsive and Neuroprotective AMPA Antagonist
2002 · Serge Mignani, Georg Andrees Bohme, et al. · Bioorganic & Medicinal Chemistry · 35
Neuroprotective Profile of Riluzole in In Vivo Models of Acute Neurodegenerative Diseases
1997 · J. M. Stutzmann, F. Wahl, et al. · CNS Drug Reviews · 25
Indeno[1,2-b]pyrazin-2,3-diones: A New Class of Antagonists at the Glycine Site of the NMDA Receptor with Potent in Vivo Activity
2000 · Patrick Jimonet, Yves Ribeill, et al. · Journal of Medicinal Chemistry · 23
Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPA and NMDA glycine-site antagonists active in vivo
1999 · Patrick Jimonet, Alain Boireau, et al. · Bioorganic & Medicinal Chemistry Letters · 22
Acute effects of irradiation on the rat brain: protection by glutamate blockade
1995 · Faouzia Alaoui, Jeremy Pratt, et al. · European Journal of Pharmacology · 19
Enoxaparin Reduces Cerebral Edemaafter Photothrombotic Injury in the Rat
1998 · J. Pratt, P. Boudeau, et al. · Pathophysiology of Haemostasis and Thrombosis · 17
Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative
1994 · P. Jimonet, M. Barreau, et al. · Bioorganic & Medicinal Chemistry · 17
4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives
2000 · Jean-Marie Stutzmann, Georg Andrees Bohme, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Profiling of Energy Metabolism in Olanzapine‐Induced Weight Gain in Rats and Its Prevention by the CB1‐Antagonist AVE1625
2010 · Michaela Liebig, Matthias Gossel, et al. · Obesity · 15
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Neuroprotective effects of colchicine in the gerbil model of cerebral ischaemia
1994 · Jeremy Pratt, Michel Roux, et al. · Neuroscience Letters · 13
8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno-[1,2-e]pyrazines: highly potent in vivo AMPA antagonists
2000 · Serge Mignani, Georg Andrees Bohme, et al. · Bioorganic & Medicinal Chemistry Letters · 12
Bioisosteres of 9-Carboxymethyl-4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent In Vivo AMPA antagonists with longer durations of action
2001 · Patrick Jimonet, Georg Andrees Bohme, et al. · Bioorganic & Medicinal Chemistry Letters · 11
Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]indeno[1,2-e]pyrazin-8- and -9-carboxylic (acetic) acid AMPA antagonists
2000 · Jeremy Pratt, Patrick Jimonet, et al. · Bioorganic & Medicinal Chemistry Letters · 11
The effect of riluzole and mannitol on cerebral oedema after cryogenic injury in the mouse
1999 · Jeremy Pratt, Christelle Archambaud, et al. · Neuroscience Letters · 11
Synthesis and pharmacological properties of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, a new competitive AMPA/KA receptor antagonist
1999 · Serge Mignani, Jean-Claude Aloup, et al. · Drug Development Research · 10
Synthesis of anticonvulsive AMPA antagonists
2001 · Jean-Marie Stutzmann, Georg Andrees Bohme, et al. · Bioorganic & Medicinal Chemistry Letters · 9
Works count: 29
Citation count: 1,127
H-index: 16
I10-index: 24
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