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Changjie Wu

Observed name: Wu, Changjie
ORCID: 0009-0004-9170-9388
Observed ORCID: 0009-0004-9170-9388
OpenAlex ID: A5074705122
Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells
2018 · Changjie Wu, Junfang Lyu, et al. · Nature Communications · 139
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RSPO2–LGR5 signaling has tumour-suppressive activity in colorectal cancer
2014 · Changjie Wu, Sunquan Qiu, et al. · Nature Communications · 127
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Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop
2020 · Yue Zhang, Shanci Wang, et al. · Cancer Letters · 98
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth
2017 · Junfang Lyu, Eun Ju Yang, et al. · Cancer Letters · 79
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics
2020 · Junfang Lyu, Eun Ju Yang, et al. · Nature Communications · 66
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METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer
2023 · Kangyue Sun, Lu Chen, et al. · Cell Death and Disease · 63
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LIMK1 m6A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation
2023 · Lu Chen, Kangyue Sun, et al. · Cancer Letters · 54
CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis
2020 · Qiuhua Lai, Qingyuan Li, et al. · Aging · 43
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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells
2019 · Baoyuan Zhang, Junfang Lyu, et al. · Acta Pharmaceutica Sinica B · 40
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Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer
2024 · Chaojun Zhu, Lan Teng, et al. · Cellular and Molecular Life Sciences · 34
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Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking
2018 · Junfang Lyu, Eun Ju Yang, et al. · International Journal of Biological Sciences · 29
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Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT
2020 · Yifan Liu, Eun Ju Yang, et al. · International Journal of Biological Sciences · 27
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Tumor-suppressive function of EZH2 is through inhibiting glutaminase
2021 · Yongfeng Liu, Cheng-e Tu, et al. · Cell Death and Disease · 22
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Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer
2024 · Zhuoyu Ding, Yiyi Wei, et al. · Journal of Translational Medicine · 21
A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker
2022 · Xuxue Guo, Mei Huang, et al. · Cancer Cell International · 19
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BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition
2018 · Baoyuan Zhang, Junfang Lyu, et al. · Oncogene · 19
Therapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis)
2024 · Zihuan Wang, Xu Zhang, et al. · Cell Death and Disease · 18
Overexpression of a novel osteopetrosis-related gene CCDC154 suppresses cell proliferation by inducing G2/M arrest
2012 · Wanqin Liao, Rongsen Zhao, et al. · Cell Cycle · 17
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VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression
2021 · Chaojun Zhu, Zihuan Wang, et al. · Frontiers in Pharmacology · 16
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Revisiting Non-Cancer Drugs for Cancer Therapy
2016 · Eun Ju Yang, Changjie Wu, et al. · Current Topics in Medicinal Chemistry · 15
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A
2018 · Yifan Liu, Eun Ju Yang, et al. · Cancer Letters · 14
ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis
2025 · Xu Zhang, Zihuan Wang, et al. · Cell Death and Differentiation · 9
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FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis
2025 · Kaiwen Qin, Haonan Zhang, et al. · npj Precision Oncology · 6
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Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine
2025 · Kejin Wang, Zhen Wang, et al. · Cell Death Discovery · 5
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ARID1A loss sensitizes colorectal cancer cells to floxuridine
2024 · Cheng Xiang, Zhen Wang, et al. · Neoplasia · 5
Works count: 40
Citation count: 989
H-index: 17
I10-index: 21
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