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Tiffany F. Chen
Observed names:
T. Chen,
TIFFANY F. CHEN,
Tiffany Chen,
Tiffany F Chen
Institution:
GentiBio (United States)
Observed institutions:
Rubius Therapeutics (United States),
Koch Institute for Integrative Cancer Research At MIT,
GentiBio (United States),
Massachusetts Institute of Technology
ORCID:
0000-0002-8089-1143
Observed ORCID:
0000-0002-8089-1143
OpenAlex ID:
A5074745433
Protein Engineering and Selection Using Yeast Surface Display
2015
·
Alessandro Angelini
, Tiffany F. Chen
, et al.
·
Methods in molecular biology
·
112
Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic
2021
·
Xuqing Zhang
, Mengyao Luo
, et al.
·
Nature Communications
·
67
PDF
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes
2024
·
Gene I. Uenishi
, Marko Repic
, et al.
·
JCI Insight
·
64
PDF
Engineering Fibronectin-Based Binding Proteins by Yeast Surface Display
2013
·
Tiffany F Chen
, Seymour de Picciotto
, et al.
·
Methods in enzymology on CD-ROM/Methods in enzymology
·
58
Triepitopic Antibody Fusions Inhibit Cetuximab-Resistant BRAF and KRAS Mutant Tumors via EGFR Signal Repression
2012
·
Jamie B. Spangler
, Mandana T. Manzari
, et al.
·
Journal of Molecular Biology
·
39
Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs
2017
·
Tiffany F. Chen
, Stephen L. Sazinsky
, et al.
·
Journal of Molecular Biology
·
19
Role of Dimerization in the Catalytic Properties of the Escherichia coli Disulfide Isomerase DsbC
2009
·
Silvia A. Arredondo
, Tiffany F. Chen
, et al.
·
Journal of Biological Chemistry
·
18
PDF
Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types
2018
·
Tiffany F. Chen
, Kevin K. Li
, et al.
·
Journal of Molecular Biology
·
9
PDF
Engineering New Protein–Protein Interactions on the β‐Propeller Fold by Yeast Cell Surface Display
2013
·
Keya Zhang
, Heng Li
, et al.
·
ChemBioChem
·
9
A phase 1 study of RTX-321, an engineered red blood cell as an artificial antigen-presenting cell expressing HLA-A*02 with the HPV-16 E7 peptide and 4-1BB ligand with membrane-bound IL-12 for the treatment of HPV 16-positive cancers.
2021
·
Johanna C. Bendell
, Alexander I. Spira
, et al.
·
Journal of Clinical Oncology
·
3
Abstract PO044: RTX-321, an allogeneic red blood cell-based artificial antigen presenting cell, expressing MHC I-peptide, 4-1BBL and IL-12, engages primary human HPV-specific T cells and boosts other general immune responses
2021
·
Mengyao Luo
, Shamael S. Dastagir
, et al.
·
Cancer Immunology Research
·
2
Abstract 3260: Engineered red-cell therapeutics (RCT) as artificial antigen presenting cells promotein vivoexpansion and anti-tumor activity of antigen specific T cells
2019
·
Xuqing Zhang
, Shamael R. Dastagir
, et al.
·
Immunology
·
2
Engineered Erythrocytes As an Anti-Tumor Therapy through Induction of Apoptosis or Immune-Checkpoint Inhibition
2016
·
Sivan Elloul
, Claire Depew
, et al.
·
Blood
·
2
An allogeneic CD19 targeted Engineered Treg approach for treating B cell mediated autoimmune diseases 2260315
2026
·
Payam Zarin
, Christopher Moore
, et al.
·
The Journal of Immunology
·
1
Abstract B062: Enabling the rapid generation of allogeneic artificial antigen presenting cell (aAPC) Red Cell Therapeutics with a loadable MHC system
2019
·
Christopher L Moore
, Sneha Pawar
, et al.
·
Molecular Cancer Therapeutics
·
1
Abstract 3260: Engineered red-cell therapeutics (RCT) as artificial antigen presenting cells promote in vivo expansion and anti-tumor activity of antigen specific T cells
2019
·
Xuqing Zhang
, Shamael R. Dastagir
, et al.
·
Cancer Research
·
1
Regulatory T cell function and engineering for next generation cell therapies
2026
·
Nathan W. Zammit
, Martina Sassone-Corsi
, et al.
·
Frontiers in Immunology
PDF
CD19 CAR Engineered T Regulatory Cells Promote Durable Immune Tolerance in Experimental Systemic Lupus Erythematosus
2026
·
Travis Drow
, Matteo Doglio
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
ST2 enforces a ‘repair-ready’ Treg phenotype that homes to and ameliorates neuroinflammation 2260164
2026
·
Nathan Zammit
, Maegan Hoover
, et al.
·
The Journal of Immunology
Modular engineering of Tregs for the treatment of inflammatory and autoimmune diseases 2259867
2026
·
Payam Zarin
, Gene Uenishi
, et al.
·
The Journal of Immunology
GNTI-932: A Targeted, Scalable, and Hypoimmune Allogeneic Engineered Treg therapy for the treatment of Inflammatory Bowel Disease 2251383
2026
·
Martina Sassone-Corsi
, Jennifer Yam
, et al.
·
The Journal of Immunology
PDF
Allogeneic Tissue Tregs Improve Disease Outcome in Models of Acute Lung and Kidney Injury 2259889
2026
·
Payam Zarin
, Maegan Hoover
, et al.
·
The Journal of Immunology
Adoptive transfer of allogeneic murine Engineered Regulatory T cells ameliorates disease in models of ischemic stroke and acute lung injury 3688
2025
·
Payam Zarin
, Maegan Hoover
, et al.
·
The Journal of Immunology
PDF
CAR19 EngTregs offer broad capacity to modulate immune tolerance and improve safety in B and T cell mediated autoimmune disorders 3850
2025
·
Victoria L. DeVault
, Matteo Doglio
, et al.
·
The Journal of Immunology
PDF
Engineered Tissue Tregs ameliorate inflammatory and ischemic diseases 3661
2025
·
Maegan Hoover
, Priya Saikumar Lakshmi
, et al.
·
The Journal of Immunology
PDF
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Works count:
35
Citation count:
407
H-index:
9
I10-index:
7
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