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Author

Emily Stepanchick

ORCID: 0000-0001-6733-3190
Observed ORCID: 0000-0001-6733-3190
OpenAlex ID: A5075085570
Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia
2021 · Timothy M. Chlon, Emily Stepanchick, et al. · Cell stem cell · 94
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The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia
2021 · Madeline Niederkorn, Chiharu Ishikawa, et al. · Leukemia · 51
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Mutational Analysis of Patients with Primary Resistance to Single-Agent Ibrutinib in Relapsed or Refractory Mantle Cell Lymphoma (MCL)
2014 · Sriram Balasubramanian, Michael Schaffer, et al. · Blood · 30
Identification of potential ibrutinib combinations in hematological malignancies using a combination high-throughput screen
2017 · Michael Schaffer, Shalini Chaturvedi, et al. · Leukemia & lymphoma/Leukemia and lymphoma · 28
DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy
2024 · Emily Stepanchick, Andrew Wilson, et al. · Leukemia · 11
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Effects of Ibrutinib on Rituximab and GA-101 Induced Antibody-Dependent Cell Cytotoxicity (ADCC) in Lymphoma Cells in Vitro
2014 · Cuc Davis, Emily Stepanchick, et al. · Blood · 9
The Most Common Somatic DDX41 Mutation (p.R525H) Causes Loss of an Essential Function and Is Selected Against in Human iPSC and Leukemia Models
2024 · Junichiro Kida, Maggie Fricker, et al. · Blood · 1
The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability
2019 · Timothy M Chlon, Emily Stepanchick, et al. · Blood · 1
Functional Characterization of Myeloid Neoplasm-associated DDX41 Variants Reveals Pathogenic Interaction with Acquired Hotspot Mutation
2026 · Julianna S. Fisher, Emily Stepanchick, et al. · bioRxiv (Cold Spring Harbor Laboratory)
The somatic hotspot mutation of DDX41 (p.R525H) elicits dominant-negative effects upon non-truncating germline variants, explaining similar disease risk as truncating variants.
2025 · Julianna Fisher, Emily Stepanchick, et al. · Blood
The somatic DDX41 hot spot mutation (p.R525H) causes skewed differentiation into plasmacytoid dendritic cells in human iPSC and leukemia models
2025 · Junichiro Kida, Maggie Fricker, et al. · Blood
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Genetic Complementation Studies Reveal That Many Disease-Associated DDX41 Variants Do Not Cause Loss of Protein Function
2023 · Timothy Chlon, Emily Stepanchick, et al. · Blood
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Abstract A46: Heterozygous mutations in DDX41 cause erythroid progenitor cell defects and cooperate with p53 mutations to cause hematologic malignancy
2023 · Timothy M Chlon, Emily Stepanchick, et al. · Blood Cancer Discovery
3040 – Heterozygous Mutations in Ddx41 Cause Erythroid Progenitor Cell Defects and Cooperate With P53 Mutations to Cause Hematologic Malignancy
2023 · Timothy Chlon, Emily Stepanchick, et al. · Experimental Hematology
Heterozygous Mutations in DDX41 Cause Erythroid Progenitor Cell Defects
2021 · Timothy M Chlon, Emily Stepanchick, et al. · Blood
The Inherited MDS Gene DDX41 Is Essential for Ribosomal RNA Processing through Regulation of Snorna Biogenesis
2020 · Timothy M Chlon, Emily Stepanchick, et al. · Blood
Abstract 365: High throughput screen to evaluate combinations with ibrutinib in various B-cell malignancies
2016 · Shalini Chaturvedi, Michael Schaffer, et al. · Cancer Research
Biomarker Analysis in a Phase Ib Study Combining Ibrutinib with R-CHOP in Patients with CD20-Positive B-Cell Non-Hodgkin Lymphoma (NHL)
2014 · Shalini Chaturvedi, Michael Schaffer, et al. · Blood
Works count: 18
Citation count: 225
H-index: 6
I10-index: 5
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