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Kristina Ellwanger
Observed name:
Ellwanger, Kristina
Observed institutions:
German Cancer Research Center,
Heidelberg University,
Affimed Therapeutics (Germany),
DKFZ-ZMBH Alliance
OpenAlex ID:
A5075328300
Loss of Dickkopf-1 Restores Neurogenesis in Old Age and Counteracts Cognitive Decline
2013
·
Désirée R.M. Seib
, Nina S. Corsini
, et al.
·
Cell stem cell
·
298
PDF
A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19 + tumor cells
2015
·
Uwe Reusch
, Johannes Duell
, et al.
·
mAbs
·
133
PDF
Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density
2008
·
Kristina Ellwanger
, Hiroaki Saito
, et al.
·
Molecular and Cellular Biology
·
112
Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia
2016
·
Uwe Reusch
, Kimberly H. Harrington
, et al.
·
Clinical Cancer Research
·
90
Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors
2021
·
Susanne Wingert
, Uwe Reusch
, et al.
·
mAbs
·
70
Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity
2019
·
Kristina Ellwanger
, Uwe Reusch
, et al.
·
mAbs
·
66
PDF
Negative Regulation of Bone Formation by the Transmembrane Wnt Antagonist Kremen-2
2010
·
Jochen Schulze
, Sebastian Seitz
, et al.
·
PLoS ONE
·
63
PDF
Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm
2007
·
Carlos Carmona-Fontaine
, Gustavo Acuña
, et al.
·
Developmental Biology
·
63
Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure
2015
·
Chiharu Kimura-Yoshida
, Kyoko Mochida
, et al.
·
EBioMedicine
·
58
PDF
Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling
2011
·
Ilkka Pietilä
, Kristina Ellwanger
, et al.
·
Developmental Biology
·
55
PDF
Trispecific antibodies for CD16A-directed NK cell engagement and dual-targeting of tumor cells
2017
·
Thorsten Gantke
, Michael Weichel
, et al.
·
Protein Engineering Design and Selection
·
50
A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma
2022
·
Satoko Kakiuchi-Kiyota
, Thorsten Ross
, et al.
·
Leukemia
·
44
Highly Specific and Effective Targeting of EGFRvIII-Positive Tumors with TandAb Antibodies
2017
·
Kristina Ellwanger
, Uwe Reusch
, et al.
·
Frontiers in Oncology
·
36
PDF
Preclinical Characterization of AFM26, a Novel B Cell Maturation Antigen (BCMA)-Directed Tetravalent Bispecific Antibody for High Affinity Retargeting of NK Cells Against Myeloma
2018
·
Thorsten Ross
, Uwe Reusch
, et al.
·
Blood
·
29
Dkk1 Regulates Ventral Midbrain Dopaminergic Differentiation and Morphogenesis
2011
·
Diogo Ribeiro
, Kristina Ellwanger
, et al.
·
PLoS ONE
·
25
PDF
Abstract 593: Highly cytotoxic EGFR/CD16A TandAbs specifically recruit NK cells to potently kill various types of solid tumors
2016
·
Kristina Ellwanger
, Uwe Reusch
, et al.
·
Cancer Research
·
24
AFM26 is a novel, highly potent BCMA/CD16A-directed bispecific antibody for high affinity NK-cell engagement in multiple myeloma.
2017
·
Thorsten Gantke
, Uwe Reusch
, et al.
·
Journal of Clinical Oncology
·
17
Cryopreservation of Natural Killer Cells Pre-Complexed with Innate Cell Engagers
2022
·
Uwe Reusch
, Kristina Ellwanger
, et al.
·
Antibodies
·
14
PDF
Trispecific Antibodies for Selective CD16A-Directed NK-Cell Engagement in Multiple Myeloma
2016
·
Thorsten Gantke
, Michael Weichel
, et al.
·
Blood
·
9
Selection of bispecific antibodies with optimal developability using FcRn‑pH‑HPLC as an optimized FcRn affinity chromatography method
2023
·
Thomas Müller
, Carolin Tasser
, et al.
·
mAbs
·
8
PDF
AFM26 - Targeting B Cell Maturation Antigen (BCMA) for NK Cell-Mediated Immunotherapy of Multiple Myeloma
2017
·
Thorsten Gantke
, Uwe Reusch
, et al.
·
Blood
·
7
Abstract 5659: AFM24, a bispecific EGFR/CD16A innate cell engager with the potential to overcome resistance to current targeted treatments for EGFR-positive malignancies
2020
·
Uwe Reusch
, Michael Damrat
, et al.
·
Cancer Research
·
6
Abstract 5671: AFM26 - A novel CD16A-directed bispecific TandAb targeting BCMA for multiple myeloma
2017
·
Thorsten Gantke
, Uwe Reusch
, et al.
·
Cancer Research
·
5
EGFR/CD16A tetravalent bispecific antibody AFM24 to engage NK-cells to kill EGFR expressing tumor cells and safety results in cynomolgus monkey studies.
2017
·
Anne Kerber
, Michael Kluge
, et al.
·
Journal of Clinical Oncology
·
4
Construction and characterization of novel CD33/CD3 tandem diabodies (TandAbs) for the treatment of acute myeloid leukemia (AML).
2015
·
Uwe Reusch
, Kimberly H. Harrington
, et al.
·
Journal of Clinical Oncology
·
3
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Works count:
53
Citation count:
1,301
H-index:
17
I10-index:
18
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