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Kevin S. Edgar

Observed names: Edgar, Kevin, Edgar, Kevin S; id_orcid 0000-0002-8057-0104, Edgar, Kevin; id_orcid 0000-0002-8057-0104, K Edgar, K S Edgar, K. Edgar, K.S. Edgar, Kevin Edgar, Kevin S Edgar
ORCID: 0000-0002-8057-0104
Observed ORCID: 0000-0002-8057-0104
OpenAlex ID: A5075405596
Reactive oxygen species signalling in the diabetic heart: emerging prospect for therapeutic targeting
2017 · Adam J Wilson, Eleanor K Gill, et al. · Heart · 178
Targeting QKI-7 in vivo restores endothelial cell function in diabetes
2020 · Chunbo Yang, Magdalini Eleftheriadou, et al. · Nature Communications · 59
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Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2
2017 · Declan McLaughlin, Youyou Zhao, et al. · British Journal of Pharmacology · 52
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Reduced Nitro-oxidative Stress and Neural Cell Death Suggests a Protective Role for Microglial Cells in TNFα −/− Mice in Ischemic Retinopathy
2010 · Laura Stevenson, Nuria Matesanz, et al. · Investigative Ophthalmology & Visual Science · 44
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Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart
2020 · Mihaela Ghita, Eleanor K. Gill, et al. · Radiotherapy and Oncology · 40
Metabolically-inactive glucagon-like peptide-1(9–36)amide confers selective protective actions against post-myocardial infarction remodelling
2016 · Emma Robinson, Mitchel Tate, et al. · Cardiovascular Diabetology · 34
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Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats
2022 · Michael O’Hare, Gema Esquiva, et al. · JCI Insight · 24
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Hyperoxia Depletes (6R)-5,6,7,8-Tetrahydrobiopterin Levels in the Neonatal Retina
2015 · Kevin S. Edgar, Nuria Matesanz, et al. · American Journal Of Pathology · 22
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A novel dual-fluorescence strategy for functionally validating microRNA targets in 3′ untranslated regions: regulation of the inward rectifier potassium channel Kir2.1 by miR-212
2012 · Dana Goldoni, Janet M. Yarham, et al. · Biochemical Journal · 21
BH4-Mediated Enhancement of Endothelial Nitric Oxide Synthase Activity Reduces Hyperoxia-Induced Endothelial Damage and Preserves Vascular Integrity in the Neonate
2017 · Kevin S. Edgar, Orla M. Galvin, et al. · Investigative Ophthalmology & Visual Science · 20
eNOS Overexpression Exacerbates Vascular Closure in the Obliterative Phase of OIR and Increases Angiogenic Drive in the Subsequent Proliferative Stage
2012 · Kevin Edgar, Thomas A. Gardiner, et al. · Investigative Ophthalmology & Visual Science · 20
NOX4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes post-ischaemic revascularization
2019 · Karla M O’Neill, David C Campbell, et al. · Cardiovascular Research · 19
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Single-Cell RNA Sequencing Reveals Cardiac Fibroblast-Specific Transcriptomic Changes in Dilated Cardiomyopathy
2024 · Adam Russell-Hallinan, Oisín Cappa, et al. · Cells · 18
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ECSIT is a critical limiting factor for cardiac function
2021 · Linan Xu, Fiachra Humphries, et al. · JCI Insight · 18
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Spatial Gene Expression Changes in the Mouse Heart After Base-Targeted Irradiation
2022 · Gerard M. Walls, Mihaela Ghita, et al. · International Journal of Radiation Oncology*Biology*Physics · 17
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Downregulation of PPARα during Experimental Left Ventricular Hypertrophy is Critically Dependent on Nox2 NADPH Oxidase Signalling
2020 · Adam P. Harvey, Emma Robinson, et al. · International Journal of Molecular Sciences · 13
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Dose-dependent changes in cardiac function, strain and remodelling in a preclinical model of heart base irradiation
2024 · Mihaela Ghita-Pettigrew, Kevin S. Edgar, et al. · Radiotherapy and Oncology · 11
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Deep phenotyping of a modified diabetic cardiomyopathy mouse model which reflects clinical disease progression
2025 · Narainrit Karuna, Lauren Kerrigan, et al. · Diabetology & Metabolic Syndrome · 9
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A multimodality assessment of the protective capacity of statin therapy in a mouse model of radiation cardiotoxicity
2023 · Gerard M. Walls, Mihaela Ghita, et al. · Radiotherapy and Oncology · 9
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Author Correction: Targeting QKI-7 in vivo restores endothelial cell function in diabetes
2020 · Chunbo Yang, Magdalini Eleftheriadou, et al. · Nature Communications · 9
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PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia
2023 · Shun Hay Pun, Karla M. O’Neill, et al. · Cells · 7
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BH4 supplementation reduces retinal cell death in ischaemic retinopathy
2023 · Kevin S. Edgar, Ciara Cunning, et al. · Scientific Reports · 6
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Restoration of NOX4 signalling reverses endothelial colony-forming cell angiogenic dysfunction associated with experimental and clinical diabetes
2025 · Karla M. O’Neill, Kevin S. Edgar, et al. · Stem Cell Research & Therapy · 2
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8 Nadph oxidase 4 is a major regulator of cord blood-derived endothelial colony-forming cells which promotes postischemic revascularisation
2018 · Karla M O’Neill, David C Campbell, et al. · Heart · 2
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Sacubitril/Valsartan as a Cardiac Radioprotector
2026 · Mihaela Ghita-Pettigrew, Brianna N. Kerr, et al. · International Journal of Radiation Oncology*Biology*Physics · 1
Works count: 71
Citation count: 660
H-index: 15
I10-index: 17
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