Author

Alexi Nott

Observed names: Nott, A, Nott, Alexi

Institutions: UK Dementia Research Institute, Imperial College London

Observed institutions: Howard Hughes Medical Institute, Duke University, University of California San Diego, MRC Laboratory for Molecular Cell Biology, Duke Medical Center, UK Dementia Research Institute, University College London, Imperial College London, Massachusetts Institute of Technology, Medical Research Council

ORCID: 0000-0002-2029-7193

Observed ORCID: 0000-0002-2029-7193

OpenAlex ID: A5075471045

Brain cell type–specific enhancer–promoter interactome maps and disease - risk association

2019 · Alexi Nott, Inge R. Holtman, et al. · Science · 710

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Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes

2015 · Ram Madabhushi, Fan Gao, et al. · Cell · 698

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S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons

2008 · Alexi Nott, P. Marc Watson, et al. · Nature · 428

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

2019 · Mashito Sakai, Ty D. Troutman, et al. · Immunity · 415

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Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

2016 · Omer Durak, Fan Gao, et al. · Nature Neuroscience · 242

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HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

2020 · Ping-Chieh Pao, Debasis Patnaik, et al. · Nature Communications · 216

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A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development

2016 · Justyna Nitarska, Jacob G. Smith, et al. · Cell Reports · 174

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Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior

2016 · Alexi Nott, Jemmie Cheng, et al. · Nature Neuroscience · 110

S -nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration

2016 · Uthpala Seneviratne, Alexi Nott, et al. · Proceedings of the National Academy of Sciences · 97

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Nuclei isolation of multiple brain cell types for omics interrogation

2021 · Alexi Nott, Johannes C. M. Schlachetzki, et al. · Nature Protocols · 78

Somatic mosaicism reveals clonal distributions of neocortical development

2022 · Martin W. Breuss, Xiaoxu Yang, et al. · Nature · 70

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Dorsal hippocampal α7 and α4β2 nicotinic receptors and memory

2006 · Alexi Nott, Edward D. Levin · Brain Research · 70

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration

2013 · Alexi Nott, Justyna Nitarska, et al. · Proceedings of the National Academy of Sciences · 61

Nitric Oxide-mediated epigenetic mechanisms in developing neurons

2009 · Alexi Nott, Antonella Riccio · Cell Cycle · 58

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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration

2020 · Nader Morshed, William T. Ralvenius, et al. · Molecular Systems Biology · 48

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Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome

2022 · Murat Yildirim, Chloe Delepine, et al. · eLife · 43

Cell state-dependent allelic effects and contextual Mendelian randomization analysis for human brain phenotypes

2025 · Alexander Haglund, Verena Zuber, et al. · Nature Genetics · 40

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CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks

2025 · Leyla Abbasova, Paulina Urbanaviciute, et al. · Nature Communications · 35

Artificial intelligence for neurodegenerative experimental models

2023 · Sarah J. Marzi, Brian M. Schilder, et al. · Alzheimer s & Dementia · 35

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Genetic insights into immune mechanisms of Alzheimer’s and Parkinson’s disease

2023 · Alexi Nott, Inge R. Holtman · Frontiers in Immunology · 29

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HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex

2015 · Alexi Nott, Sukhee Cho, et al. · Neuroepigenetics · 27

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Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways

2025 · Aydan Askarova, Reuben M. Yaa, et al. · PLoS Genetics · 18

Immune memory in the brain

2018 · Alexi Nott, Christopher K. Glass · Nature · 13

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The brain neurovascular epigenome and its association with dementia

2025 · Kevin Chris Ziegler, Aydan Askarova, et al. · Neuron · 9

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Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association

2019 · Alexi Nott, Inge R. Holtman, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 8

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Works count: 57

Citation count: 3,786

H-index: 21

I10-index: 23