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Laurent Fraisse

Towards the sustainable discovery and development of new antibiotics
2021 · Marcus Miethke, Marco Pieroni, et al. · Nature Reviews Chemistry · 1,273
Targeting DnaN for tuberculosis therapy using novel griselimycins
2015 · Angela Kling, Peer Lukat, et al. · Science · 327
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
2023 · Melissa L. Boby, Daren Fearon, et al. · Science · 252
The antimalarial ferroquine: from bench to clinic
2011 · C. Biot, F. Nosten, et al. · Parasite · 189
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Selection of a trioxaquine as an antimalarial drug candidate
2008 · Frédéric Coslédan, Laurent Fraisse, et al. · Proceedings of the National Academy of Sciences · 159
Probing the Role of the Covalent Linkage of Ferrocene into a Chloroquine Template
2006 · Christophe Biot, Wassim Daher, et al. · Journal of Medicinal Chemistry · 99
Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum
2020 · Bernd Stadelmayer, Audrey Diederichs, et al. · Journal of Hepatology · 94
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Facing the escalating burden of dengue: Challenges and perspectives
2023 · Gathsaurie Neelika Malavige, Peter Sjö, et al. · PLOS Global Public Health · 91
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Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition
2019 · Elaine Ballinger, John Mosior, et al. · Science · 80
Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure
2006 · Wassim Daher, Christophe Biot, et al. · Malaria Journal · 78
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Efficacy of NZ2114, a Novel Plectasin-Derived Cationic Antimicrobial Peptide Antibiotic, in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus
2011 · Yan Q. Xiong, Wessam Abdel Hady, et al. · Antimicrobial Agents and Chemotherapy · 74
Free radical depolymerization of hyaluronan by maillard reaction products
1998 · V Deguine, M Menasche, et al. · International Journal of Biological Macromolecules · 74
Reliability of Antimalarial Sensitivity Tests Depends on Drug Mechanisms of Action
2010 · Sharon Wein, Marjorie Maynadier, et al. · Journal of Clinical Microbiology · 66
A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters
2002 · Laurent Fraisse, Marie Claude Bonnet, et al. · Analytical Biochemistry · 65
In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum
2008 · Maud Henry, Sébastien Briolant, et al. · Antimicrobial Agents and Chemotherapy · 64
Metallophthalocyanine-catalyzed oxidation of catechols by H2O2 and its surrogates
1997 · Alexander Sorokin, Laurent Fraisse, et al. · Journal of Molecular Catalysis A Chemical · 62
Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate
2012 · S Wein, M Maynadier, et al. · British Journal of Pharmacology · 54
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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
2021 · James M. Murithi, Cécile Pascal, et al. · Science Translational Medicine · 49
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Observations on the reduction of non-activated carboxylates by Clostridium formicoaceticum with carbon monoxide or formate and the influence of various viologens
1988 · Laurent Fraisse, Helmut Simon · Archives of Microbiology · 45
A stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score
2022 · Jan-Alexis Tremblay, Florian Peron, et al. · Annals of Intensive Care · 41
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Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells
2018 · Clément Bonamy, Emmanuel Sechet, et al. · Scientific Reports · 41
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A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry
2014 · Diana Marcela Penarete-Vargas, Anaïs Boisson, et al. · PLoS ONE · 39
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PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models
2025 · Morgane Gossez, Clara Vigneron, et al. · Nature Communications · 37
In Vitro Metabolism of Ferroquine (ssr97193) in Animal and Human Hepatic Models and Antimalarial Activity of Major Metabolites on Plasmodium Falciparum
2006 · Wassim Daher, Lydie Pelinski, et al. · Drug Metabolism and Disposition · 34
Flux-dependent increase in the stoichiometry of charge translocation by mitochondrial ATPase/ATP synthase induced by almitrine
1990 · Michel Rigoulet, Laurent Fraisse, et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 34
Works count: 59
Citation count: 3,772
H-index: 27
I10-index: 40
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