Author

Sabine Depauw

Observed names: Depauw, S., Depauw, Sabine, S. Depauw

Observed institutions: Engelhardt Institute of Molecular Biology, Centre National de la Recherche Scientifique, Russian Academy of Sciences, Inserm, Institut Pasteur, Georgia State University, Johannes Gutenberg University Mainz, Université de Lille, Institut Pasteur de Lille, Centre Hospitalier Universitaire de Lille, Centre de Recherche Jean Pierre Aubert, Institut pour la Recherche sur le Cancer de Lille, Institut de Biologie de Lille, Centre de Recherches en Cancérologie de Lille, Université Paris Descartes, Immuno-Rhumathologie moléculaire, Institut Servier, Université Lille Nord de France, Université de Strasbourg

ORCID: 0000-0002-8148-7900

Observed ORCID: 0000-0002-8148-7900

OpenAlex ID: A5075576447

Targeting Transcription Factors for Cancer Treatment

2018 · Mélanie Lambert, Samy Jambon, et al. · Molecules · 364

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Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

2012 · Raja Nhili, Paul Peixoto, et al. · Nucleic Acids Research · 75

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Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia

2019 · Mélanie Lambert, Meryem Alioui, et al. · Cancers · 73

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Water-Mediated Binding of Agents that Target the DNA Minor Groove

2011 · Yang Liu, Arvind Kumar, et al. · Journal of the American Chemical Society · 70

Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: Design, synthesis, DNA binding and antitumor cell cytotoxicity

2009 · Thomas Lemster, Ulf Pindur, et al. · European Journal of Medicinal Chemistry · 61

Novel Substituted Benzothiophene and Thienothiophene Carboxanilides and Quinolones: Synthesis, Photochemical Synthesis, DNA-Binding Properties, Antitumor Evaluation and 3D-Derived QSAR Analysis

2012 · Maja Aleksić, Branimir Bertoša, et al. · Journal of Medicinal Chemistry · 59

Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding Properties

2010 · Livio Racané, Vesna Tralić-Kulenović, et al. · Journal of Medicinal Chemistry · 57

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

2008 · Paul Peixoto, Yang Liu, et al. · Nucleic Acids Research · 56

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Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties

2017 · Maja Cindrić, Samy Jambon, et al. · European Journal of Medicinal Chemistry · 54

New anticancer active and selective phenylene-bisbenzothiazoles: Synthesis, antiproliferative evaluation and DNA binding

2013 · Livio Racané, Sandra Kraljević Pavelić, et al. · European Journal of Medicinal Chemistry · 48

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

2019 · Sabine Depauw, Mélanie Lambert, et al. · Journal of Medicinal Chemistry · 45

DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity, and Specificity for a TTAA Site

2010 · Manoj Munde, Arvind Kumar, et al. · Journal of Molecular Biology · 44

Structure–activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines

2009 · Sébastien Madonna, Christophe Béclin, et al. · European Journal of Medicinal Chemistry · 44

Synthesis, antitumor activity and DNA binding features of benzothiazolyl and benzimidazolyl substituted isoindolines

2018 · Irena Sović, Samy Jambon, et al. · Bioorganic & Medicinal Chemistry · 28

The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine

2014 · Manoj Munde, Arvind Kumar, et al. · Biochemistry · 28

Structure‐Dependent Binding of Arylimidamides to the DNA Minor Groove

2013 · Yun Chai, Manoj Munde, et al. · ChemBioChem · 26

Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: Synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSAR analysis and DNA-binding properties

2013 · Maja Aleksić, Branimir Bertoša, et al. · European Journal of Medicinal Chemistry · 26

Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair

2015 · Ananya Paul, Rupesh Nanjunda, et al. · Bioorganic & Medicinal Chemistry Letters · 25

Novel phenyl and pyridyl substituted derivatives of isoindolines: Synthesis, antitumor activity and DNA binding features

2014 · Irena Sović, Sandra Kraljević Pavelić, et al. · European Journal of Medicinal Chemistry · 22

Synthesis, Cytotoxic Activity, and Mechanism of Action of Furo[2,3-c]acridin-6-one and Benzo[b]furo[3,2-h]acridin-6-one Analogues of Psorospermin and Acronycine

2008 · Sabrina Boutefnouchet, Nicolas Gaboriaud-Kolar, et al. · Journal of Medicinal Chemistry · 21

Synthesis, Antitumor Activity, and Mechanism of Action of Benzo[ b ]chromeno[6,5- g ][1,8]naphthyridin-7-one Analogs of Acronycine

2014 · Wen Tian, Rodrigue Yougnia, et al. · Journal of Medicinal Chemistry · 18

In vitro anticancer activity, toxicity and structure–activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii

2011 · Benjamin Le Calvé, Benjamin Lallemand, et al. · Toxicology and Applied Pharmacology · 18

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents

2011 · Constance Genès, Gaëlle Lenglet, et al. · European Journal of Medicinal Chemistry · 15

Synthesis and biological evaluation of dialkylaminoalkylamino benzo[c][1,7] and [1,8]phenanthrolines as antiproliferative agents

2010 · Tuba Şerbetçi, Constance Genès, et al. · European Journal of Medicinal Chemistry · 15

Protein recognition of the S23906-1–DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

2013 · Gaëlle Lenglet, Sabine Depauw, et al. · Biochemical Journal · 14

Works count: 54

Citation count: 1,375

H-index: 20

I10-index: 30