Author

António Francisco Ambrósio

Observed names: A Ambrósio, A F Ambrósio, A. Ambrosio, A. F. Ambrósio, A.F. Ambrósio, Ambrosio A., Ambrósio, António F., Ambrósio, António Francisco, Antonio Ambrosio, Antonio F. Ambrosio, Antonio F. Ambrósio, Anto´nio F. Ambro´sio, Anto´nio Francisco Ambro´sio, António Ambrósio, António F Ambrósio, António F. Ambrósio, António Francisco Rosa Gomes Ambrósio, António. F. Ambrósio

Institutions: Association for Innovation and Biomedical Research on Light and Image, Centro de Inovação em Biomedicina e Biotecnologia, University of Coimbra

Observed institutions: Unidade Local de Saúde de Coimbra, Italian Institute of Technology, Center for Nano Science and Technology, Association for Innovation and Biomedical Research on Light and Image, Centro de Neurociências e Biologia Celular, Centro de Inovação em Biomedicina e Biotecnologia, University of Coimbra

ORCID: 0000-0002-0477-1641

Observed ORCID: 0000-0002-0477-1641

OpenAlex ID: A5075909802

PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

2020 · Peter M. J. Quinn, Paula I. Moreira, et al. · Acta Neuropathologica Communications · 514

TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

2010 · Célia A. Aveleira, Cheng-Mao Lin, et al. · Diabetes · 415

Mechanisms of Action of Carbamazepine and Its Derivatives, Oxcarbazepine, BIA 2-093, and BIA 2-024

2002 · António F. Ambrósio, Patrício Soares-da-Silva, et al. · Neurochemical Research · 303

Inducible Nitric Oxide Synthase Isoform Is a Key Mediator of Leukostasis and Blood-Retinal Barrier Breakdown in Diabetic Retinopathy

2007 · Ermelindo C. Leal, Ayyakkannu Manivannan, et al. · Investigative Ophthalmology & Visual Science · 250

Contribution of Microglia‐Mediated Neuroinflammation to Retinal Degenerative Diseases

2015 · Maria H. Madeira, Raquel Boia, et al. · Mediators of Inflammation · 234

Inside the Diabetic Brain: Role of Different Players Involved in Cognitive Decline

2015 · Joana M. Gaspar, Filipa I. Baptista, et al. · ACS Chemical Neuroscience · 185

Calcium Dobesilate Inhibits the Alterations in Tight Junction Proteins and Leukocyte Adhesion to Retinal Endothelial Cells Induced by Diabetes

2010 · Ermelindo C. Leal, João Martins, et al. · Diabetes · 135

Neuroprotective Strategies for Retinal Ganglion Cell Degeneration: Current Status and Challenges Ahead

2020 · Raquel Boia, Noelia Ruzafa, et al. · International Journal of Molecular Sciences · 133

Methamphetamine transiently increases the blood–brain barrier permeability in the hippocampus: Role of tight junction proteins and matrix metalloproteinase-9

2011 · Tânia Martins, Sofia Baptista, et al. · Brain Research · 125

Heme Oxygenase-1 Protects Retinal Endothelial Cells against High Glucose- and Oxidative/Nitrosative Stress-Induced Toxicity

2012 · Áurea F. Castilho, Célia A. Aveleira, et al. · PLoS ONE · 103

Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists

1999 · António F. Ambrósio, Ana P. Silva, et al. · Neuropharmacology · 102

Retinal texture biomarkers may help to discriminate between Alzheimer’s, Parkinson’s, and healthy controls

2019 · Ana Nunes, Gilberto Silva, et al. · PLoS ONE · 99

Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

2020 · Renato Socodato, Camila C. Portugal, et al. · Cell Reports · 93

Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety

2016 · L Caetano, H Pinheiro, et al. · Molecular Psychiatry · 92

Regulation of claudins in blood-tissue barriers under physiological and pathological states

2013 · Andreia Gonçalves, António Francisco Ambrósio, et al. · Tissue Barriers · 90

Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood–retinal barrier in a type 2 diabetes animal model

2011 · A. Gonçalves, E. Leal, et al. · Diabetes Obesity and Metabolism · 90

Sweet Stress: Coping With Vascular Dysfunction in Diabetic Retinopathy

2018 · Ana R. Santiago, Raquel Boia, et al. · Frontiers in Physiology · 89

Blockade of microglial adenosine A2A receptor suppresses elevated pressure‐induced inflammation, oxidative stress, and cell death in retinal cells

2019 · Inês Dinis Aires, Raquel Boia, et al. · Glia · 88

Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury

2015 · Maria H. Madeira, Raquel Boia, et al. · Translational research · 88

Having a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative Diseases

2017 · Maria H. Madeira, Raquel Boia, et al. · Mediators of Inflammation · 87

Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure

2015 · Maria H. Madeira, Filipe Elvas, et al. · Journal of Neuroinflammation · 87

The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer’s Disease: Critical Aspects to Unravel

2019 · Samuel Chiquita, Ana C. Rodrigues-Neves, et al. · Molecular Neurobiology · 86

Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer’s Disease

2017 · Jorge Valero, Liliana Bernardino, et al. · Journal of Alzheimer s Disease · 86

Dipeptidyl peptidase-IV inhibition prevents blood–retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats

2014 · Andreia Gonçalves, Catarina Marques, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 85

Viewing the choroid: where we stand, challenges and contradictions in diabetic retinopathy and diabetic macular oedema

2016 · António Campos, Elisa J. Campos, et al. · Acta Ophthalmologica · 83

Works count: 242

Citation count: 8,710

H-index: 54

I10-index: 151