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Rustom Falahati
Observed names:
Falahati, R.,
R Falahati,
R. Falahati
Institution:
Arcus Biosciences (United States)
Observed institutions:
University of California, San Francisco,
George Washington University,
Allakos (United States),
University of California San Francisco Medical Center,
Arcus Biosciences (United States)
OpenAlex ID:
A5076682533
Receptor‐stimulated oxidation of SHP‐2 promotes T‐cell adhesion through SLP‐76–ADAP
2005
·
Jaeyul Kwon
, Cheng‐Kui Qu
, et al.
·
The EMBO Journal
·
126
PDF
Novel Approach to Inhibit Asthma-Mediated Lung Inflammation Using Anti-CD147 Intervention
2006
·
William M Gwinn
, Jesse M Damsker
, et al.
·
The Journal of Immunology
·
117
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice
2019
·
Bradford A. Youngblood
, Emily C. Brock
, et al.
·
International Archives of Allergy and Immunology
·
111
PDF
Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis
2016
·
Paul J. Bryce
, Rustom Falahati
, et al.
·
Journal of Allergy and Clinical Immunology
·
106
Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis
2019
·
Bradford A. Youngblood
, Emily C. Brock
, et al.
·
JCI Insight
·
104
Discovery, Function, and Therapeutic Targeting of Siglec-8
2020
·
Bradford A. Youngblood
, John Leung
, et al.
·
Cells
·
93
PDF
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
2020
·
Julia Schanin
, Simon Gebremeskel
, et al.
·
Mucosal Immunology
·
79
PDF
Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity
2010
·
Alessandra Jales
, Rustom Falahati
, et al.
·
Immunology
·
30
CD45‐associated protein promotes the response of primary CD4 T cells to low‐potency T‐cell receptor (TCR) stimulation and facilitates CD45 association with CD3/TCR and Lck
2007
·
David Leitenberg
, Rustom Falahati
, et al.
·
Immunology
·
29
Changes in the Role of the CD45 Protein Tyrosine Phosphatase in Regulating Lck Tyrosine Phosphorylation during Thymic Development
2007
·
Rustom Falahati
, David Leitenberg
·
The Journal of Immunology
·
24
Modulation of CD4 Th Cell Differentiation by Ganglioside GD1a In Vitro
2005
·
Weiping Shen
, Rustom Falahati
, et al.
·
The Journal of Immunology
·
24
PDF
Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation
2008
·
Katrin Hacke
, Rustom Falahati
, et al.
·
Immunologic Research
·
23
Role of antigen-specific regulatory CD4+CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF.IX
2013
·
Y Shi
, R Falahati
, et al.
·
Gene Therapy
·
13
PDF
Chemoselection of Allogeneic HSC After Murine Neonatal Transplantation Without Myeloablation or Post-transplant Immunosuppression
2012
·
Rustom Falahati
, Jianqing Zhang
, et al.
·
Molecular Therapy
·
11
PDF
Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development
2008
·
Rustom Falahati
, David Leitenberg
·
The Journal of Immunology
·
7
PDF
A Recombinant Antibody to Siglec-8 Shows Selective ADCC Activity Against Mast Cells from Systemic Mastocytosis Patients
2015
·
Rustom Falahati
, Jessica Bright
, et al.
·
Blood
·
4
Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis (HYP4P.302)
2015
·
Laurie Kenney
, Paul Bryce
, et al.
·
The Journal of Immunology
·
4
MRGPRX2 Activation Triggers a Distinct Transcriptional Response That is Enriched in Chronic Spontaneous Urticaria and Atopic Dermatitis Lesions 2251623
2026
·
Emily Brown
, Nina Serwas
, et al.
·
The Journal of Immunology
1025 AB102 is a potent and orally bioavailable small molecule inhibitor of MRGPRX2
2026
·
N.K. Serwas
, L. Zhang
, et al.
·
Journal of Investigative Dermatology
71930 Inhibition of Mast Cell Restricted MRGPRX2 In Dermal Diseases
2026
·
Nina K. Serwas
, Diane Nathaniel
, et al.
·
Journal of the American Academy of Dermatology
Inhibition of Mast Cell Specific MRGPRX2 In Dermal and Mucosal Diseases
2026
·
Diane Nathaniel
, Emily Brown
, et al.
·
Journal of Allergy and Clinical Immunology
Supplementary Material for: AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice
2019
·
Youngblood, B.A.
, Brock, E.C.
, et al.
·
Figshare
Ak002, a Novel Siglec-8 Antibody Depletes Human Eosinophils and Inhibits Anaphylaxis in Humanized Mice
2018
·
A. Chang
, B. Youngblood
, et al.
·
Annals of Allergy Asthma & Immunology
A Novel Therapeutic Target for the Treatment of Eosinophilic Disorders
2015
·
Fanny Legrand
, Alexandra Alpaugh
, et al.
·
Journal of Allergy and Clinical Immunology
Tumor derived gangliosides promote regulatory cell activity (98.10)
2010
·
Alessandra Jales
, Rustom Falahati
, et al.
·
The Journal of Immunology
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Works count:
29
Citation count:
905
H-index:
13
I10-index:
14
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