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Manuel Roqueta‐Rivera
Observed names:
M Roqueta-Rivera,
M. Roqueta-Riverta,
Manuel Roqueta-Rivera
Institution:
Enanta Pharmaceuticals (United States)
Observed institutions:
University of Illinois Urbana-Champaign,
Sanford Burnham Prebys Medical Discovery Institute,
Enanta Pharmaceuticals (United States)
ORCID:
0000-0001-6011-0226
Observed ORCID:
0000-0001-6011-0226
OpenAlex ID:
A5076931912
Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism
2014
·
Selma Masri
, Paul Rigor
, et al.
·
Cell
·
299
PDF
Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration
2009
·
Chad K. Stroud
, Takayuki Y. Nara
, et al.
·
Journal of Lipid Research
·
173
Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice
2009
·
Manuel Roqueta-Rivera
, Chad K. Stroud
, et al.
·
Journal of Lipid Research
·
161
An SREBP-Responsive microRNA Operon Contributes to a Regulatory Loop for Intracellular Lipid Homeostasis
2013
·
Tae-Il Jeon
, Ryan M. Esquejo
, et al.
·
Cell Metabolism
·
121
PDF
SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation
2016
·
Manuel Roqueta-Rivera
, Ryan M. Esquejo
, et al.
·
Cell Metabolism
·
77
PDF
Deficiency in the Omega-3 Fatty Acid Pathway Results in Failure of Acrosome Biogenesis in Mice1
2011
·
Manuel Roqueta-Rivera
, Timothy L. Abbott
, et al.
·
Biology of Reproduction
·
76
Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum
2020
·
Ryan M. Esquejo
, Manuel Roqueta-Rivera
, et al.
·
Cell chemical biology
·
34
Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Δ6-desaturase knockout (6-DS KO) mice: Beneficial effects of arachidonic acid
2009
·
Mira Rosenblat
, Nina Volkova
, et al.
·
Atherosclerosis
·
29
Characterization of EDP-305, a Highly Potent and Selective Farnesoid X Receptor Agonist, for the Treatment of Non-alcoholic Steatohepatitis
2019
·
Mary Chau
, Yang Li
, et al.
·
International Journal of Gastroenterology
·
16
Reproducible lung protective effects of a TGFβR1/ALK5 inhibitor in a bleomycin‐induced and spirometry‐confirmed model of IPF in male mice
2024
·
Asbjørn Graver Petersen
, Stefanie H. Korntner
, et al.
·
Physiological Reports
·
7
Discovery of a Potent and Selective KIT inhibitor for Treatment of Mast Cell-Mediated Diseases
2026
·
Manuel Roqueta-Rivera
, Tessa Cressey
, et al.
·
Journal of Allergy and Clinical Immunology
·
1
Therapeutic effects of ALK5i on pulmonary function and fibrosis in a high-fat diet + bleomycin-induced and spirometry-confirmed mouse model of IPF
2023
·
Asbjørn Graver Petersen
, Jamal Bousamaki
, et al.
·
European Respiratory Journal
·
1
A novel FXR agonist EDP-297 exerts anti-inflammatory and hepatoprotective effects in human liver 3D microtissues and rodent NASH and liver injury models
2020
·
Mary Chau
, Manuel Roqueta-Rivera
, et al.
·
Journal of Hepatology
·
1
EDP-305, a highly selective and potent farnesoid X receptor agonist, favorably regulates the expression of key fibrogenic genes in vitro and in vivo
2018
·
Y. Li
, J. Shang
, et al.
·
Journal of Hepatology
·
1
The function of SREBP‐1a in high sucrose diet‐mediated metabolic disease
2012
·
Seung-Soon Im
, Manuel Roqueta-Rivera
, et al.
·
The FASEB Journal
·
1
EPS-3903 Is a Potent and Selective Oral STAT6 Inhibitor that Blocks Th2 Inflammation in an Ovalbumin Asthma Mouse Model 2253997
2026
·
Yaohui Nie
, Manuel Roqueta-Rivera
, et al.
·
The Journal of Immunology
Discovery and Characterization of a Potent and Selective Oral Inhibitor of STAT6 for the Treatment of Allergic Diseases 2257118
2026
·
Kelsey Garlick
, Joyce Sweeney
, et al.
·
The Journal of Immunology
PDF
C34-04 EPS-3903 is a Potent and Selective Oral STAT6 Inhibitor that Blocks Th2 Inflammation in a House Dust Mite-Induced Asthma Mouse Model
2026
·
Y Nie
, M Roqueta-Rivera
, et al.
·
American Journal of Respiratory and Critical Care Medicine
HSD17B13 inhibitors are hepatoprotective and anti-inflammatory in a mouse model of autoimmune hepatitis
2023
·
Manuel Roqueta-Rivera
, Yaohui Nie
, et al.
·
Journal of Hepatology
Pharmacologic inhibition of HSD17B13 is hepatoprotective in mouse models of liver injury
2022
·
Manuel Roqueta-Rivera
, Mary Chau
, et al.
·
Journal of Hepatology
FRI-340-In vivo effects of a novel inhibitor of apoptosis signal-regulating kinase 1 in mouse models of liver injury and metabolic disease
2019
·
Manuel Roqueta-Rivera
, Mary Chau
, et al.
·
Journal of Hepatology
Su1500 - EDP-305 Favorably Regulates Lipoprotein Mechanism In Vitro
2018
·
Mary Chau
, Manuel Roqueta-Rivera
, et al.
·
Gastroenterology
EDP-305 modulates lipoprotein metabolism via distinct chromatin and microRNA regulatory mechanisms
2018
·
M. Roqueta-Riverta
, M. Chau
, et al.
·
Journal of Hepatology
SETDB2 Mediates Metabolic Stress in Liver
2015
·
Manuel Roqueta‐Rivera
, Peter Phelan
, et al.
·
The FASEB Journal
Protein kinase A (PKA) interferes with the processing and activity of sterol regulatory element binding proteins (SREBPs)
2013
·
Ryan Magadan Esquejo
, Peter E. Phelan
, et al.
·
The FASEB Journal
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Works count:
26
Citation count:
998
H-index:
9
I10-index:
9
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