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Junlian Gu

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy
2016 · Junlian Gu, Yanli Cheng, et al. · Diabetes · 196
Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway
2014 · Zhiguo Zhang, Shudong Wang, et al. · Journal of Molecular and Cellular Cardiology · 188
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice
2016 · Jingjing Zhang, Yanli Cheng, et al. · Clinical Science · 159
Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway
2017 · Shudong Wang, Yonggang Wang, et al. · Cell Death and Disease · 139
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Molecular mechanisms of doxorubicin-induced cardiotoxicity: novel roles of sirtuin 1-mediated signaling pathways
2021 · Jie Wang(a), Jingjing Zhang, et al. · Cellular and Molecular Life Sciences · 113
Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis
2018 · Junlian Gu, Shudong Wang, et al. · Cell Death and Disease · 113
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Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway
2015 · Chi Zhang, Zhifeng Huang, et al. · Diabetologia · 113
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Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability
2017 · Zhifeng Huang, Yi Tan, et al. · Cell Reports · 104
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Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2
2022 · Jie Wang(a), Yufeng Tang, et al. · Redox Biology · 101
C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21
2016 · Hao Wu, Lili Kong, et al. · Diabetologia · 101
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Bone Marrow Mesenchymal Stem Cell-Derived Exosomal miRNA-29c Decreases Cardiac Ischemia/Reperfusion Injury Through Inhibition of Excessive Autophagy via the PTEN/Akt/mTOR Signaling Pathway
2020 · Te Li, Junlian Gu, et al. · Circulation Journal · 82
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Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene
2023 · Qi Sun, Diming Liu, et al. · Communications Biology · 76
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Curcumin derivative WZ35 efficiently suppresses colon cancer progression through inducing ROS production and ER stress-dependent apoptosis.
2017 · Junru Zhang, Zhiguo Feng, et al. · PubMed · 59
Low-Dose Radiation Induces Cell Proliferation in Human Embryonic Lung Fibroblasts but not in Lung Cancer Cells
2016 · Xinyue Liang, Junlian Gu, et al. · Dose-Response · 54
Zinc rescues obesity‐induced cardiac hypertrophy via stimulating metallothionein to suppress oxidative stress‐activated BCL 10/ CARD 9/p38 MAPK pathway
2017 · Shudong Wang, Junlian Gu, et al. · Journal of Cellular and Molecular Medicine · 53
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HDAC3 inhibition in diabetic mice may activate Nrf2 preventing diabetes-induced liver damage and FGF21 synthesis and secretion leading to aortic protection
2018 · Jian Zhang, Zheng Xu, et al. · American Journal of Physiology-Endocrinology and Metabolism · 49
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Knockdown of HIF-1α by siRNA-expressing plasmid delivered by attenuated Salmonella enhances the antitumor effects of cisplatin on prostate cancer
2017 · Junlian Gu, Yang Li, et al. · Scientific Reports · 46
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Pharmacological Activity of Flavonoid Quercetin and Its Therapeutic Potential in Testicular Injury
2023 · Xiaohui Zhang, Yufeng Tang, et al. · Nutrients · 43
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Insoluble and Soluble Dietary Fibers from Kiwifruit (Actinidia deliciosa) Modify Gut Microbiota to Alleviate High-Fat Diet and Streptozotocin-Induced TYPE 2 Diabetes in Rats
2022 · Kunli Wang, Yuxiao Wang, et al. · Nutrients · 41
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p53 at the Crossroads between Doxorubicin-Induced Cardiotoxicity and Resistance: A Nutritional Balancing Act
2023 · Yuanfang Guo, Yufeng Tang, et al. · Nutrients · 39
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Zinc deficiency exacerbates while zinc supplement attenuates cardiac hypertrophy in high-fat diet-induced obese mice through modulating p38 MAPK-dependent signaling
2016 · Shudong Wang, Manyu Luo, et al. · Toxicology Letters · 39
Resveratrol and FGF1 Synergistically Ameliorates Doxorubicin-Induced Cardiotoxicity via Activation of SIRT1-NRF2 Pathway
2022 · Guangping Lu, Qingbo Liu, et al. · Nutrients · 38
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Epigenetic Regulation Associated With Sirtuin 1 in Complications of Diabetes Mellitus
2021 · Jie Wang(a), Shudong Wang, et al. · Frontiers in Endocrinology · 38
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Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts
2017 · Junlian Gu, Xiaoqing Yan, et al. · Diabetes · 38
Regulatory mechanisms of Sesn2 and its role in multi-organ diseases
2020 · Jie Wang(b), Shudong Wang, et al. · Pharmacological Research · 35
Works count: 69
Citation count: 2,534
H-index: 29
I10-index: 44
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