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Author

Mads Mørup Nygaard

Observed names: Mads M. Nygaard, Mads Mo̷rup Nygaard, Mads Nygaard, Nygaard, Mads Mørup
Institution: Gubra (Denmark)
ORCID: 0000-0003-1642-4724
Observed ORCID: 0000-0003-1642-4724
OpenAlex ID: A5077672450
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
2018 · Anthea Di Rita, Angelo Peschiaroli, et al. · Nature Communications · 291
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An Efficient Method for Estimating the Hydrodynamic Radius of Disordered Protein Conformations
2017 · Mads Nygaard, Birthe B. Kragelund, et al. · Biophysical Journal · 134
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
2019 · Michael Lückmann, Mette Trauelsen, et al. · Proceedings of the National Academy of Sciences · 46
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Machine-Learning-Guided Peptide Drug Discovery: Development of GLP-1 Receptor Agonists with Improved Drug Properties
2024 · Jens Christian Nielsen, Claudia Hjo̷rringgaard, et al. · Journal of Medicinal Chemistry · 33
The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer
2016 · Mads Nygaard, Thilde Terkelsen, et al. · Frontiers in Molecular Biosciences · 31
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Orchestration of signaling by structural disorder in class 1 cytokine receptors
2020 · Pernille Seiffert, Katrine Bugge, et al. · Cell Communication and Signaling · 29
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Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: Potential implications in breast tumorigenesis
2014 · Chi Zhang, Ibtissem Cherifi, et al. · Molecular and Cellular Endocrinology · 17
Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2
2023 · Christian R. O. Bartling, Flora Alexopoulou, et al. · Journal of Medicinal Chemistry · 15
A single mutation Gln142Lys doubles the catalytic activity of VPR, a cold adapted subtilisin-like serine proteinase
2016 · Kristinn R. Óskarsson, Mads Nygaard, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 9
Analyzing Biomolecular Ensembles
2019 · Matteo Lambrughi, Matteo Tiberti, et al. · Methods in molecular biology · 7
A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling
2015 · Chi Zhang, Mads Nygaard, et al. · Journal of Biological Chemistry · 4
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Specificity-driven protein binder design with Odin-Multi
2026 · Valentas Brasas, Charlotte R. Christensen, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
Supporting data for "Specificity-driven protein binder design with Odin-Multi"
2026 · Brasas, Valentas, Christensen, Charlotte R., et al. · Zenodo (CERN European Organization for Nuclear Research)
De novo designed cyclic MC4R peptide agonist reduces food intake in mice
2026 · Victor Møller, Julie Maria Johansen, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Streamline - machine learning guided development of novel GLP-1 receptor agonists with improved drug properties
2025 · Randi Mikkelsen, Nina Buch-Manson, et al. · Endocrine Abstracts
StreaMLine - Machine learning guided development of novel GLP-1 receptor agonists
2024 · Claudia Hjørringgaard, Jens Christian Nielsen, et al. · European Peptide Symposium (EPS)
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Engineering mRNA display for GPCR drug discovery – de novo discovery of cyclic peptide GLP1R binders
2024 · Esther Meron, Jens C. Nielsen, et al. · European Peptide Symposium (EPS)
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Works count: 17
Citation count: 618
H-index: 9
I10-index: 8
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