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Oscar Mammoliti
Observed names:
Mammoliti, O.,
Mammoliti, Oscar,
O. Mammoliti
Institution:
Galapagos (Belgium)
Observed institutions:
Janssen (Belgium),
Rega Institute for Medical Research,
Galapagos (France),
University of Southampton,
Galapagos (Belgium),
KU Leuven
show all 6
ORCID:
0000-0002-1521-9254
Observed ORCID:
0000-0002-1521-9254
OpenAlex ID:
A5077843060
Discovery ofN-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-lH-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent
2017
·
Steven E. Van der Plas
, Hans Kelgtermans
, et al.
·
Journal of Medicinal Chemistry
·
65
Strategy for the Synthesis of Pyridazine Heterocycles and Their Derivatives
2013
·
Hassen Bel Abed
, Oscar Mammoliti
, et al.
·
The Journal of Organic Chemistry
·
63
Identification and Characterization of Novel CFTR Potentiators
2018
·
Maarten Gees
, Sara Musch
, et al.
·
Frontiers in Pharmacology
·
47
PDF
Organophosphorus-catalyzed diaza-Wittig reaction: application to the synthesis of pyridazines
2014
·
Hassen Bel Abed
, Oscar Mammoliti
, et al.
·
Organic & Biomolecular Chemistry
·
35
PDF
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis
2021
·
Oscar Mammoliti
, Adeline Palisse
, et al.
·
Journal of Medicinal Chemistry
·
34
Progress Toward JAK1-Selective Inhibitors
2015
·
Christel J Menet
, Oscar Mammoliti
, et al.
·
Future Medicinal Chemistry
·
29
Simple approach to the synthesis of 3-fluoro pyrazolo[1,5-a]pyrimidine analogues
2013
·
Hassen Bel Abed
, Oscar Mammoliti
, et al.
·
Tetrahedron Letters
·
28
Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis
2021
·
Steven E. Van der Plas
, Hans Kelgtermans
, et al.
·
Journal of Medicinal Chemistry
·
26
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases
2021
·
Oscar Mammoliti
, Koen Jansen
, et al.
·
Journal of Medicinal Chemistry
·
22
Discovery of Potent and Brain-Penetrant Bicyclic NLRP3 Inhibitors with Peripheral and Central In Vivo Activity
2025
·
Oscar Mammoliti
, Rodrigo Carbajo
, et al.
·
Journal of Medicinal Chemistry
·
19
Discovery of GLPG3667, a Selective ATP Competitive Tyrosine Kinase 2 Inhibitor for the Treatment of Autoimmune Diseases
2024
·
Oscar Mammoliti
, Sébastien Martina
, et al.
·
Journal of Medicinal Chemistry
·
19
A short and convenient strategy for the synthesis of pyridazines via Diaza–Wittig reaction
2012
·
Hassen Bel Abed
, Oscar Mammoliti
, et al.
·
Tetrahedron Letters
·
18
PDF
Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector
2024
·
Mathieu Pizzonero
, Rhalid Akkari
, et al.
·
Journal of Medicinal Chemistry
·
13
A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor
2013
·
Hassen Bel Abed
, Omprakash Bande
, et al.
·
Tetrahedron Letters
·
12
PDF
Synthesis and anion-binding properties of new disulfonamide-based receptors
2009
·
Oscar Mammoliti
, Sara Allasia
, et al.
·
Tetrahedron
·
12
Direct access to 1-aryl-5-amino-1,2,4-triazoles and [1,2,4]triazolo[1,5-a]pyridines by two new single-step reactions from 1,3,4-thiadiazol-2-amines
2012
·
Oscar Mammoliti
, Evelyne M. Quinton
, et al.
·
Tetrahedron
·
10
Design of a potent and selective dual JAK1/TYK2 inhibitor
2024
·
Oscar Mammoliti
, Christel Menet
, et al.
·
Bioorganic & Medicinal Chemistry
·
5
HBsAg Suppression by a New Series of HBV RNA Destabilizers: Discovery and Effects on In Vitro Neurite Outgrowth
2026
·
Jacques Huck
, Caroline Joannesse
, et al.
·
Journal of Medicinal Chemistry
·
3
Discovery and Characterization of GLPG3808, a PAPD5/7 Inhibitor for Suppression of Hepatitis B Viral Infections
2026
·
Oscar Mammoliti
, Adeline Palisse
, et al.
·
Journal of Medicinal Chemistry
·
2
Discovery of GLPG4471, a potent and selective IRAK4 inhibitor for the treatment of inflammatory and autoimmune diseases
2025
·
Oscar Mammoliti
, Florence Bonnaterre
, et al.
·
Bioorganic & Medicinal Chemistry Letters
CCDC 2122384: Experimental Crystal Structure Determination
2021
·
Mammoliti, Oscar
, Jansen, Koen
, et al.
·
The Cambridge Structural Database
CCDC 2122349: Experimental Crystal Structure Determination
2021
·
Mammoliti, Oscar
, Jansen, Koen
, et al.
·
The Cambridge Structural Database
Correction to “Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis”
2021
·
Steven E. Van der Plas
, Hans Kelgtermans
, et al.
·
Journal of Medicinal Chemistry
PDF
ChemInform Abstract: Organophosphorus‐Catalyzed Diaza‐Wittig Reaction: Application to the Synthesis of Pyridazines.
2015
·
Hassen Bel Abed
, Oscar Mammoliti
, et al.
·
ChemInform
ChemInform Abstract: A Novel and Convenient Strategy for the Synthesis of Phthalazines from an Aryne Precursor.
2014
·
Hassen Bel Abed
, Omprakash Bande
, et al.
·
ChemInform
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Works count:
38
Citation count:
462
H-index:
13
I10-index:
16
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