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Radha Krishan Shandil

Observed names: R K Shandil, R. K. SHANDIL, R. K. Shandil, R.K. SHANDIL, R.K. Shandil, Radha K. Shandil, Radha Krishan SHANDIL, Radha Shandil, Radha. K. Shandil, Radhakrishnan Shandil, Shandil Rk
Observed institutions: AstraZeneca (United Kingdom), Vignan's Foundation for Science, Technology & Research, University of Pavia, Central Research Institute, AstraZeneca (India), AstraZeneca (United States), Foundation for Neglected Disease Research, Post Graduate Institute of Medical Education and Research, École Polytechnique Fédérale de Lausanne
ORCID: 0000-0002-0908-1340
Observed ORCID: 0000-0002-0908-1340
OpenAlex ID: A5078612453
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
2009 · Vadim Makarov, Giulia Manina, et al. · Science · 752
Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis
2003 · Ramesh Jayaram, Sheshagiri Gaonkar, et al. · Antimicrobial Agents and Chemotherapy · 338
Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis : Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacy
2006 · Radha K. Shandil, Ramesh Jayaram, et al. · Antimicrobial Agents and Chemotherapy · 207
Isoniazid Pharmacokinetics-Pharmacodynamics in an Aerosol Infection Model of Tuberculosis
2004 · Ramesh Jayaram, Radha. K. Shandil, et al. · Antimicrobial Agents and Chemotherapy · 172
Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo
2013 · Pravin S. Shirude, Radha Shandil, et al. · Journal of Medicinal Chemistry · 168
Discovery of Imidazo[1,2- a ]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis
2017 · Subramanyam J. Tantry, Shankar D. Markad, et al. · Journal of Medicinal Chemistry · 125
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis
2019 · Richa Mishra, Sakshi Kohli, et al. · Science Translational Medicine · 114
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1,4-Azaindole, a Potential Drug Candidate for Treatment of Tuberculosis
2014 · Monalisa Chatterji, Radha Shandil, et al. · Antimicrobial Agents and Chemotherapy · 108
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Randomized Trial of Metformin With Anti-Tuberculosis Drugs for Early Sputum Conversion in Adults With Pulmonary Tuberculosis
2021 · Chandrasekaran Padmapriydarsini, Megha Mamulwar, et al. · Clinical Infectious Diseases · 98
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4-Aminoquinolone Piperidine Amides: Noncovalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity
2014 · Maruti Naik, Vaishali Humnabadkar, et al. · Journal of Medicinal Chemistry · 97
Lead Optimization of 1,4-Azaindoles as Antimycobacterial Agents
2014 · Pravin S. Shirude, Radha K. Shandil, et al. · Journal of Medicinal Chemistry · 90
In Vitro and In Vivo Efficacy of β-Lactams against Replicating and Slowly Growing/Nonreplicating Mycobacterium tuberculosis
2013 · Suresh Solapure, Neela Dinesh, et al. · Antimicrobial Agents and Chemotherapy · 80
Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice
2009 · Disha Awasthy, Sheshagiri Gaonkar, et al. · Microbiology · 61
Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria
2024 · Lukas Junk, Volker M. Schmiedel, et al. · Nature Communications · 52
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Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis
2013 · Shahul Hameed P, Suresh Solapure, et al. · Antimicrobial Agents and Chemotherapy · 49
Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity
2019 · Manjunatha M. R, Radha Shandil, et al. · ACS Medicinal Chemistry Letters · 40
Whole cell screen based identification of spiropiperidines with potent antitubercular properties
2015 · Subramanyam J. Tantry, Giulia Degiacomi, et al. · Bioorganic & Medicinal Chemistry Letters · 34
Evaluation of the Therapeutic Potential of Mesenchymal Stem Cells (MSCs) in Preclinical Models of Autoimmune Diseases
2022 · Radha Krishan Shandil, Saumya Dhup, et al. · Stem Cells International · 33
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Vaginosis: Advances in new therapeutic development and microbiome restoration
2022 · Balasubramaniam Mohankumar, R.K. Shandil, et al. · Microbial Pathogenesis · 33
Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway
2016 · Subramanyam J. Tantry, Vikas Shinde, et al. · MedChemComm · 29
Study of the Interaction between Bacteriophage T4 asiA andEscherichia coliς70, Using the Yeast Two-Hybrid System: Neutralization of asiA Toxicity toE. coliCells by Coexpression of a Truncated ς70Fragment
1999 · Umender K. Sharma, Sudha Ravishankar, et al. · Journal of Bacteriology · 29
Pharmacokinetics and dose response of anti-TB drugs in rat infection model of tuberculosis
2014 · Naveen Kumar, K.G. Vishwas, et al. · Tuberculosis · 28
Discovery of FNDR-20123, a histone deacetylase inhibitor for the treatment of Plasmodium falciparum malaria
2020 · Vijay Potluri, Radha K. Shandil, et al. · Malaria Journal · 27
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High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of Escherichia coli Penicillin Binding Protein 1b
2003 · B. Chandrakala, Radha K. Shandil, et al. · Antimicrobial Agents and Chemotherapy · 27
Effect of Coadministration of Moxifloxacin and Rifampin on Mycobacterium tuberculosis in a Murine Aerosol Infection Model
2012 · V. Balasubramanian, S. Solapure, et al. · Antimicrobial Agents and Chemotherapy · 24
Works count: 69
Citation count: 3,074
H-index: 24
I10-index: 35
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