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Patrick K. Tumwebaze
Observed names:
Patrick K Tumwebaze,
Patrick Tumwebaze,
Tumwebaze, Patrick K.
Institution:
Infectious Diseases Research Collaboration
Observed institutions:
University of California, San Francisco,
Brown University,
Infectious Diseases Research Collaboration,
Makerere University,
University of Tübingen
ORCID:
0000-0002-5933-1432
Observed ORCID:
0000-0002-5933-1432
OpenAlex ID:
A5078708996
Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda
2023
·
Melissa D. Conrad
, Victor Asua
, et al.
·
New England Journal of Medicine
·
223
PDF
Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda
2020
·
Victor Asua
, Melissa D Conrad
, et al.
·
The Journal of Infectious Diseases
·
205
PDF
Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda
2022
·
Patrick K. Tumwebaze
, Melissa D. Conrad
, et al.
·
Nature Communications
·
146
PDF
The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC
2020
·
Robert Verity
, Ozkan Aydemir
, et al.
·
Nature Communications
·
115
PDF
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance
2018
·
Laura A. Kirkman
, Wenhu Zhan
, et al.
·
Proceedings of the National Academy of Sciences
·
98
PDF
Changing Antimalarial Drug Sensitivities in Uganda
2017
·
Stephanie A. Rasmussen
, Frida G. Ceja
, et al.
·
Antimicrobial Agents and Chemotherapy
·
81
Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study
2021
·
Patrick K Tumwebaze
, Thomas Katairo
, et al.
·
The Lancet Microbe
·
75
PDF
Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays
2015
·
Roland A. Cooper
, Melissa D. Conrad
, et al.
·
Antimicrobial Agents and Chemotherapy
·
67
PDF
Impact of Antimalarial Treatment and Chemoprevention on the Drug Sensitivity of Malaria Parasites Isolated from Ugandan Children
2015
·
Patrick Tumwebaze
, Melissa D. Conrad
, et al.
·
Antimicrobial Agents and Chemotherapy
·
62
PDF
Changing antimalarial drug resistance patterns identified by surveillance at three sites in Uganda
2016
·
Patrick Tumwebaze
, Stephen Tukwasibwe
, et al.
·
The Journal of Infectious Diseases
·
59
PDF
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
2021
·
James M. Murithi
, Cécile Pascal
, et al.
·
Science Translational Medicine
·
49
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
2021
·
Michael J. Palmer
, Xiaoyi Deng
, et al.
·
Journal of Medicinal Chemistry
·
47
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
2022
·
Laura E. de Vries
, Patrick A. M. Jansen
, et al.
·
Nature Communications
·
42
PDF
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice
2021
·
Wenhu Zhan
, Hao Zhang
, et al.
·
Angewandte Chemie International Edition
·
41
Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors
2019
·
Wenhu Zhan
, Joseph Visone
, et al.
·
Journal of Medicinal Chemistry
·
36
Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019–2024
2025
·
Martin Okitwi
, Stephen Orena
, et al.
·
Nature Communications
·
35
PDF
Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda
2013
·
Mariana De Niz
, Alice C Eziefula
, et al.
·
Malaria Journal
·
35
PDF
Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity
2016
·
Joaniter I. Nankabirwa
, Melissa D. Conrad
, et al.
·
Antimicrobial Agents and Chemotherapy
·
33
Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria
2022
·
Benjamin R. Taft
, Fumiaki Yokokawa
, et al.
·
Journal of Medicinal Chemistry
·
32
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance–Mediating Polymorphisms in Uganda
2017
·
Melissa D Conrad
, Daniel Mota
, et al.
·
The Journal of Infectious Diseases
·
29
PDF
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance
2024
·
Madeline R. Luth
, Karla P. Godinez-Macias
, et al.
·
Science
·
27
Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda
2014
·
Sheila Nankoberanyi
, George W Mbogo
, et al.
·
Malaria Journal
·
27
PDF
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials
2020
·
Papireddy Kancharla
, Rozalia A. Dodean
, et al.
·
Journal of Medicinal Chemistry
·
22
Fitness Consequences of Plasmodium falciparum pfmdr1 Polymorphisms Inferred from Ex Vivo Culture of Ugandan Parasites
2013
·
Edwin Ochong
, Patrick K. Tumwebaze
, et al.
·
Antimicrobial Agents and Chemotherapy
·
22
PDF
Structure–Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II
2023
·
Hao Zhang
, John Ginn
, et al.
·
Journal of Medicinal Chemistry
·
17
PDF
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Works count:
60
Citation count:
1,772
H-index:
22
I10-index:
30
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