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Christel J. Menet

Observed names: C. Menet, Christel J Menet, Christel Menet, Menet, Christel
ORCID: 0000-0003-3928-5608
Observed ORCID: 0000-0003-3928-5608
OpenAlex ID: A5078964923
Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases
2013 · Luc Van Rompaey, René Galien, et al. · The Journal of Immunology · 237
Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634
2014 · Christel J. Menet, Stephen R Fletcher, et al. · Journal of Medicinal Chemistry · 130
Type II Kinase Inhibitors: An Opportunity in Cancer for Rational Design
2013 · Javier Blanc, Raphael Geney, et al. · Anti-Cancer Agents in Medicinal Chemistry · 105
Advances in the Discovery of Selective JAK Inhibitors
2013 · Christel J. Menet, Luc Van Rompaey, et al. · Progress in medicinal chemistry · 80
Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: formal synthesis of (–)-kainic acid
2001 · Jonathan Clayden, Christel J. Menet, et al. · Chemical Communications · 62
Synthesis of (−)-kainic acid using chiral lithium amides in an asymmetric dearomatizing cyclization
2002 · Jonathan Clayden, Christel J Menet, et al. · Tetrahedron · 61
IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases
2023 · Stéphanie Lavazais, Manja Jargosch, et al. · Science Translational Medicine · 51
Wandering beyond small molecules: peptides as allosteric protein modulators
2021 · Morgane Mannes, Charlotte Martin, et al. · Trends in Pharmacological Sciences · 50
Dearomatizing Anionic Cyclization of Substituted N-Cumyl-N-benzyl- benzamides on Treatment with LDA: Synthesis of Partially Saturated Substituted Isoindolones
2000 · Jonathan Clayden, Christel J. Menet, et al. · Organic Letters · 49
Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs
2022 · Toon Laeremans, Zara A. Sands, et al. · Frontiers in Molecular Biosciences · 45
2,3-Dihydroisoindolones by cyclisation and rearomatisation of lithiated benzamides
2003 · Jonathan Clayden, Christel J. Menet · Tetrahedron Letters · 45
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis
2021 · Oscar Mammoliti, Adeline Palisse, et al. · Journal of Medicinal Chemistry · 34
Stereospecific Photochemical Ring Expansion of Lithiated Benzamides
2003 · Jonathan Clayden, Faye E. Knowles, et al. · Journal of the American Chemical Society · 33
Synthesis of α-methyl kainic acid by stereospecific lithiation–dearomatizing cyclization of a chiral benzamide
2003 · Jonathan Clayden, Faye E Knowles, et al. · Tetrahedron Letters · 32
Progress Toward JAK1-Selective Inhibitors
2015 · Christel J Menet, Oscar Mammoliti, et al. · Future Medicinal Chemistry · 29
Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist
2024 · Thomas Fontaine, Andreas Busch, et al. · Nature Communications · 26
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Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis
2021 · Steven E. Van der Plas, Hans Kelgtermans, et al. · Journal of Medicinal Chemistry · 26
Stereospecific DearomatisingCyclisation of Tertiary α-Amidoorganolithiums
2003 · Jonathan Clayden, Faye E. Knowles, et al. · Synlett · 23
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases
2021 · Oscar Mammoliti, Koen Jansen, et al. · Journal of Medicinal Chemistry · 22
Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein‐Coupled Receptors for Application in Drug Discovery
2021 · Morgane Mannes, Charlotte Martin, et al. · Angewandte Chemie International Edition · 19
A Dual Inhibition, a Better Solution: Development of a JAK1/TYK2 inhibitor
2018 · Christel J Menet · Journal of Medicinal Chemistry · 19
Toward Selective TYK2 Inhibitors As Therapeutic Agents for the Treatment of Inflammatory Diseases
2014 · Christel J Menet · Pharmaceutical Patent Analyst · 18
Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): Identification of a new group III metabotropic glutamate receptor selective agonist
2006 · Stephan Schann, Christel Menet, et al. · Bioorganic & Medicinal Chemistry Letters · 16
‘meso-Selective’ functionalisation of N-benzyl-α-methylbenzylamine derivatives by α-lithiation and alkylation
2002 · Ryan A Bragg, Jonathan Clayden, et al. · Tetrahedron Letters · 11
Expediting drug discovery: recent advances in fast medicinal chemistry--optimization of hits and leads.
2006 · Paul J Edwards, Brigitte Allart, et al. · PubMed · 8
Works count: 48
Citation count: 1,246
H-index: 19
I10-index: 24
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