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Author

Scott Sproul

OpenAlex ID: A5079503723
In vivo genome editing of the albumin locus as a platform for protein replacement therapy
2015 · Rajiv Sharma, Xavier M. Anguela, et al. · Blood · 296
Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing
2018 · Kanut Laoharawee, Russell C. DeKelver, et al. · Molecular Therapy · 125
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ZFN-Mediated In Vivo Genome Editing Corrects Murine Hurler Syndrome
2018 · Li Ou, Russell C. DeKelver, et al. · Molecular Therapy · 84
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AAV2/6 Gene Therapy in a Murine Model of Fabry Disease Results in Supraphysiological Enzyme Activity and Effective Substrate Reduction
2020 · Makiko Yasuda, Marshall W. Huston, et al. · Molecular Therapy — Methods & Clinical Development · 57
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ZFN-mediated in vivo gene editing in hepatocytes leads to supraphysiologic α-Gal A activity and effective substrate reduction in Fabry mice
2021 · Silvere Pagant, Marshall W. Huston, et al. · Molecular Therapy · 23
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ZFN-Mediated Gene Targeting at the Albumin Locus in Liver Results in Therapeutic Levels of Human FIX in Mice and Non-Human Primates
2015 · Thomas Wechsler, Kathleen E. Meyer, et al. · Blood · 5
ZFN-mediated genome editing of albumin “safe harbor” in vivo results in supraphysiological levels of human IDS, IDUA and GBA in mice
2015 · Russell DeKelver, Michelle Rohde, et al. · Molecular Genetics and Metabolism · 3
479. ZFN-Mediated In Vivo Genome Editing Results in Supraphysiological Levels of Lysosomal Enzymes Deficient in Hunter and Hurler Syndrome and Gaucher Disease
2015 · Thomas Wechsler, Russel DeKelver, et al. · Molecular Therapy · 2
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ZFN-mediated in vivo genome editing of hepatocytes results in phenotypic correction in murine MPS I and MPS II models
2018 · Thomas Wechsler, Russell DeKelver, et al. · Molecular Genetics and Metabolism · 1
Liver-based expression of the human alpha-galactosidase A gene in a murine Fabry model results in continuous therapeutic levels of enzyme activity and effective substrate reduction
2018 · Marshall W. Huston, Makiko Yasuda, et al. · Molecular Genetics and Metabolism · 1
ZFN-mediated in vivo genome editing results in therapeutic levels of α-galactosidase A and effective substrate reduction in Fabry knockout mice
2018 · Silvere Pagant, Marshall W. Huston, et al. · Molecular Genetics and Metabolism · 1
Liver-based expression of the human alpha-galactosidase A gene (GLA) in a murine Fabry model results in continuous supra-physiological enzyme activity and effective substrate reduction
2017 · Marshall W. Huston, Makiko Yasuda, et al. · Molecular Genetics and Metabolism · 1
ZFN-mediated in vivo genome editing results in phenotypic correction in murine MPS I and MPS II models
2017 · Russell DeKelver, Li Ou, et al. · Molecular Genetics and Metabolism · 1
484. In Vivo Zinc-Finger Nuclease Mediated Iduronate-2-Sulfatase (IDS) Target Gene Insertion and Correction of Metabolic Disease in a Mouse Model of Mucopolysaccharidosis Type II (MPS II)
2016 · Kanut Laoharawee, Russell DeKelver, et al. · Molecular Therapy · 1
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485. ZFN-Mediated Liver-Targeting Gene Therapy Corrects Systemic and Neurological Disease of Mucopolysaccharidosis Type I
2016 · Li Ou, Russell DeKelver, et al. · Molecular Therapy · 1
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ZFN-mediated correction of murine MPS I model by expression of the human IDUA cDNA from the albumin “safe harbor” locus
2016 · Li Ou, Russell DeKelver, et al. · Molecular Genetics and Metabolism · 1
Abstract 3071: Accurate and sensitive detection of KRAS mutations in heterogeneous cancer specimens
2011 · Yun Bao, David Merrill, et al. · Cancer Research · 1
ZFN-mediated in vivo genome editing results in supraphysiological levels of human iduronate 2-sulfatase and phenotypic correction in a murine MPS II model
2016 · Russell DeKelver, Kanut Laoharawee, et al. · Molecular Genetics and Metabolism
Abstract 5609: Mechanisms of acquired resistance to selective PI3K inhibitors in breast cancer cell lines
2012 · Carol Lynn O'Brien, Jill Spoerke, et al. · Cancer Research
Works count: 19
Citation count: 604
H-index: 5
I10-index: 5
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