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Galia Oberkovitz
Observed name:
G Oberkovitz
Institution:
Karyopharm Therapeutics (United States)
Observed institutions:
Ben-Gurion University of the Negev,
Karyopharm Therapeutics (United States),
BioLineRx Ltd. (Israel),
Weizmann Institute of Science
OpenAlex ID:
A5079738556
Proapoptotic BID Is an ATM Effector in the DNA-Damage Response
2005
·
Iris Kamer
, Rachel Sarig
, et al.
·
Cell
·
226
PDF
The ATM–BID pathway regulates quiescence and survival of haematopoietic stem cells
2012
·
Maria Maryanovich
, Galia Oberkovitz
, et al.
·
Nature Cell Biology
·
152
BL‐8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open‐label safety and efficacy phase 2a study
2020
·
Gautam Borthakur
, Yishai Ofran
, et al.
·
Cancer
·
43
PDF
PKCη confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells
2009
·
Noa Rotem-Dai
, Galia Oberkovitz
, et al.
·
Experimental Cell Research
·
34
PKCη expression contributes to the resistance of hodgkin's lymphoma cell lines to apoptosis
2007
·
Sara Abu-Ghanem
, Galia Oberkovitz
, et al.
·
Cancer Biology & Therapy
·
29
PDF
Nucleocytoplasmic shuttling of BID is involved in regulating its activities in the DNA-damage response
2007
·
G Oberkovitz
, L Regev
, et al.
·
Cell Death and Differentiation
·
16
CXCR4 antagonist (BL-8040) to enhance antitumor effects by increasing tumor infiltration of antigen-specific effector T-cells.
2018
·
Pankaj Gaur
, Vivek Verma
, et al.
·
Journal of Clinical Oncology
·
9
Evaluation of pharmacodynamic (PD) biomarkers in patients with metastatic pancreatic cancer treated with BL-8040, a novel CXCR4 antagonist.
2018
·
Manuel M. Hidalgo
, Ron Epelbaum
, et al.
·
Journal of Clinical Oncology
·
6
The Selective Anti Leukemic Effect of BL-8040, a Peptidic CXCR4 Antagonist, Is Mediated By Induction of Leukemic Blast Mobilization, Differentiation and Apoptosis: Results of Correlative Studies from a Ph2a Trial in Acute Myeloid Leukemia
2016
·
Gautam Borthakur
, Martin S. Tallman
, et al.
·
Blood
·
5
Effect of BL-8040, high-affinity CXCR4 antagonist, on T-cell infiltration, tumor growth, and synergy with immunomodulatory agents.
2017
·
Michal Abraham
, Inbal Mishalian
, et al.
·
Journal of Clinical Oncology
·
3
Open-label phase 1/2 study evaluating the tolerability and antitumor activity of selinexor and pembrolizumab in colorectal cancer.
2022
·
Talia Golan
, Talia Shentzer Kutiel
, et al.
·
Journal of Clinical Oncology
·
1
The CXCR4 Antagonist BL-8040 Induces a Robust Mobilization of CD34+CD38−CD45RA−CD90+ CD49f+ HSCs with Long-Term and Secondary Myeloid and Lymphoid Repopulating Activity
2017
·
Michal Abraham
, Galia Oberkovitz
, et al.
·
Blood
·
1
Final Phase IIa Study Results Evaluating the CXCR4 Antagonist BL-8040 in Combination with Cytarabine (Ara-C) for the Treatment of Relapsed/Refractory AML Patients
2016
·
Gautam Borthakur
, Martin Tallman
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
·
1
Evaluation of pharmacodynamic (PD) biomarkers in patients with metastatic pancreatic cancer treated with BL-8040, a novel CXCR4 antagonist.
2018
·
Manuel M. Hidalgo
, Ron Epelbaum
, et al.
·
Journal of Clinical Oncology
Combinatorial Targeting of Leukemia and Stromal Cells Overcomes Fms-like Tyrosine Kinase 3 (FLT3) Inhibitor Resistance in Acute Myeloid Leukemia (AML)
2017
·
Seemana Bhattacharya
, Hong Mu
, et al.
·
Clinical Lymphoma Myeloma & Leukemia
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Works count:
15
Citation count:
526
H-index:
7
I10-index:
6
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