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Nidhi Kaushal

Sigma-1 Receptors and Neurodegenerative Diseases: Towards a Hypothesis of Sigma-1 Receptors as Amplifiers of Neurodegeneration and Neuroprotection
2017 · Linda Nguyen, Brandon P. Lucke-Wold, et al. · Advances in experimental medicine and biology · 119
Conversion of a Highly Selective Sigma-1 Receptor–Ligand to Sigma-2 Receptor Preferring Ligands with Anticocaine Activity
2008 · Christophe Mésangeau, Sanju Narayanan, et al. · Journal of Medicinal Chemistry · 57
First-Time Disclosure of CVN424, a Potent and Selective GPR6 Inverse Agonist for the Treatment of Parkinson’s Disease: Discovery, Pharmacological Validation, and Identification of a Clinical Candidate
2021 · Huikai Sun, Holger Monenschein, et al. · Journal of Medicinal Chemistry · 49
Role of Sigma Receptors in Methamphetamine-Induced Neurotoxicity
2011 · Nidhi Kaushal, Rae R. Matsumoto · Current Neuropharmacology · 48
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Sigma (σ) Receptors as Potential Therapeutic Targets to Mitigate Psychostimulant Effects
2014 · Rae R. Matsumoto, Linda Nguyen, et al. · Advances in pharmacology · 47
Sigma receptors as potential therapeutic targets for neuroprotection
2014 · Linda Nguyen, Nidhi Kaushal, et al. · European Journal of Pharmacology · 42
Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia
2021 · Holly A. Reichard, Hans H. Schiffer, et al. · Journal of Medicinal Chemistry · 40
Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease
2021 · Nicola L. Brice, Hans H. Schiffer, et al. · Journal of Pharmacology and Experimental Therapeutics · 40
Synthesis and Pharmacological Evaluation of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a Cocaine Antagonist, in Rodents
2011 · Nidhi Kaushal, Matthew J. Robson, et al. · The AAPS Journal · 37
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CM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in mice
2011 · Nidhi Kaushal, Michael J. Seminerio, et al. · Neuropharmacology · 33
A Novel Substituted Piperazine, CM156, Attenuates the Stimulant and Toxic Effects of Cocaine in Mice
2010 · Yan-Tong Xu, Nidhi Kaushal, et al. · Journal of Pharmacology and Experimental Therapeutics · 33
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The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice
2012 · Michael J. Seminerio, Rolf Hansen, et al. · The International Journal of Neuropsychopharmacology · 26
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Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo
2012 · Nidhi Kaushal, Michael J. Seminerio, et al. · European Neuropsychopharmacology · 24
Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice
2010 · Michael J. Seminerio, Nidhi Kaushal, et al. · Pharmacology Biochemistry and Behavior · 22
AC927, a σ Receptor Ligand, Blocks Methamphetamine-Induced Release of Dopamine and Generation of Reactive Oxygen Species in NG108-15 Cells
2011 · Nidhi Kaushal, Meenal Elliott, et al. · Molecular Pharmacology · 21
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Balanced Activation of Striatal Output Pathways by Faster Off-Rate PDE10A Inhibitors Elicits Not Only Antipsychotic-Like Effects But Also Procognitive Effects in Rodents
2019 · Akina Harada, Nidhi Kaushal, et al. · The International Journal of Neuropsychopharmacology · 16
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Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro
2014 · Nidhi Kaushal, Matthew J. Robson, et al. · European Journal of Pharmacology · 10
SN79, A Novel Sigma (σ) ‐ 2 Receptor Antagonist, Attenuates Cocaine‐Induced Behaviors In Mice
2008 · Nidhi Kaushal, Caroline Croom, et al. · The FASEB Journal · 3
Attenuation of methamphetamine‐induced neurotoxicity by selective sigma receptor ligands: in vivo and in vitro studies
2013 · Rae Matsumoto, Nidhi Kaushal, et al. · The FASEB Journal · 1
S223. Combined Treatment With a Selective Pde10a Inhibitor Tak-063 and Antipsychotics at Subeffective Doses Produces Potent Antipsychotic-like Effects Without Exacerbating Side Effects Profile in Rodents
2018 · Kazunori Suzuki, Akina Harada, et al. · Schizophrenia Bulletin
Attenuation of methamphetamine-induced striatal neurotoxicity involves both neuronal and glial mechanisms
2014 · Rae Matsumoto, Matthew Robson, et al. · Drug and Alcohol Dependence
Evaluation of novel sigma receptor antagonists against METH-induced neurotoxicity: in vivo and in vitro studies
2012 · Nidhi Kaushal
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CM156, A Sigma (σ) Receptor Antagonist, Mitigates Stimulant And Neurotoxic Effects Of Methamphetamine In Mice
2009 · Nidhi Kaushal, Michael J. Seminerio, et al. · The FASEB Journal
Works count: 25
Citation count: 668
H-index: 16
I10-index: 17
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