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Author

Tran Ngoc Van Le

Observed name: Van Le
ORCID: 0000-0002-0342-2634
Observed ORCID: 0000-0002-0342-2634
OpenAlex ID: A5079838334
Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility
2021 · Jingwen Zhang, Zhibin He, et al. · Aging Cell · 72
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Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
2024 · Xu Han, Michelle Burrows, et al. · Cell Reports · 47
Activated Protein C Strengthens Cardiac Tolerance to Ischemic Insults in Aging
2021 · Di Ren, Julia Fedorova, et al. · Circulation Research · 25
The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease
2022 · Jiayuan Murphy, Tran Ngoc Van Le, et al. · Frontiers in Cardiovascular Medicine · 22
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Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics
2024 · Lucien Turner, Tran Ngoc Van Le, et al. · Science Immunology · 21
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Sirtuin 1 aggravates hypertrophic heart failure caused by pressure overload via shifting energy metabolism
2022 · Tran Ngoc Van Le, Linda Ines Zoungrana, et al. · Biochemical and Biophysical Research Communications · 16
Metabolic and transcriptional plasticity supports CD8+ T cell resilience and anti-tumor immunity under nutrient stress
2026 · Michael Scaglione, Montana Knight, et al. · Immunity · 7
Glutaminase inhibition ameliorates cancer-associated fibroblast lipid support of pancreatic cancer cell growth
2025 · Xu Han, Laura C. Kim, et al. · Cancer & Metabolism · 3
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Biosynthetic plasticity enables CD8+ T cell functional resilience under nutrient stress
2025 · Michael Scaglione, Montana Knight, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
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Abstract 12111: Metformin Maintains Mitochondrial Integrity and Preserve Heart From Ischemia Reperfusion Injury Through Sestrin2-AMPK Signaling
2021 · Lauryn Bates, Julia Fedorova, et al. · Circulation · 1
Nutrient-sensitive histone propionylation regulates T cell fate and function
2026 · Alison Jaccard, Kelly Rome, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Glucose availability tunes latent CD8+ T cell expansion potential through a mitogen-independent, mTOR-dependent regulatory switch
2026 · Tran Ngoc Van Le, Krittin Trihemasava, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Corrigendum: The cardiac dysfunction caused by metabolic alterations in Alzheimer's disease
2025 · Jiayuan Murphy, Tran Ngoc Van Le, et al. · Frontiers in Cardiovascular Medicine
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Abstract C038: Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment
2024 · Xu Han, Michelle Burrows, et al. · Cancer Research
Abstract 9553: Sirtuin1 Aggravates Hypertrophic Heart Failure Caused by Pressure Overload via Shifting Energy Metabolism
2022 · Meredith Krause-Hauch, Van Le, et al. · Circulation
Abstract 12199: Sirtuin1 Mediates Pressure Overload-Induced Cardiac Pathological Hypertrophy Through Regulating Mitochondrial Dynamics
2021 · Van Le, Jiayuan Murphy, et al. · Circulation
Abstract 11004: Activated Protein C Protects Human Cardiomyocytes Against Hypoxia Reoxygenation Stress-Induced Injury Through Maintaining Mitochondrial Integrity
2021 · Kayla Davitt, Julia Fedorova, et al. · Circulation
Abstract 10237: Activated Protein C Protects Neurons from Alzheimer’s Disease-Related Changes Through Reduction of Tau Hyperphosphorylation
2021 · Jiayuan Murphy, Van Le, et al. · Circulation
Works count: 18
Citation count: 217
H-index: 7
I10-index: 6
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