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Kornelia Hardes

TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
2020 · Dorothea Bestle, Miriam Ruth Heindl, et al. · Life Science Alliance · 878
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TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes
2019 · Hannah Limburg, Anne Harbig, et al. · Journal of Virology · 177
Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases
2012 · Gero L. Becker, Yinghui Lu, et al. · Journal of Biological Chemistry · 122
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Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics
2015 · Wolfgang Garten, Carolin Braden, et al. · European Journal of Cell Biology · 92
X-ray Structures of Human Furin in Complex with Competitive Inhibitors
2014 · Sven O. Dahms, Kornelia Hardes, et al. · ACS Chemical Biology · 87
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Novel Furin Inhibitors with Potent Anti‐infectious Activity
2015 · Kornelia Hardes, Gero L. Becker, et al. · ChemMedChem · 78
Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication
2017 · Jenny Kouretova, M. Zouhir Hammamy, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 52
Antiviral Potential of Natural Resources against Influenza Virus Infections
2022 · Johanna Eichberg, Elena Maiworm, et al. · Viruses · 43
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Venom biotechnology: casting light on nature’s deadliest weapons using synthetic biology
2023 · Tim Lüddecke, Anne Paas, et al. · Frontiers in Bioengineering and Biotechnology · 39
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Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin
2019 · Thuy Van Lam van, Teodora Ivanova, et al. · ChemMedChem · 37
Optimization of Substrate‐Analogue Furin Inhibitors
2017 · Teodora Ivanova, Kornelia Hardes, et al. · ChemMedChem · 35
Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides
2022 · Jonas Krämer, Tim Lüddecke, et al. · Toxins · 34
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X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket
2018 · Sven O. Dahms, Kornelia Hardes, et al. · Biochemistry · 32
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells
2015 · Yinghui Lu, Kornelia Hardes, et al. · Antiviral Research · 31
New substrate analogue furin inhibitors derived from 4-amidinobenzylamide
2011 · Gero L. Becker, Kornelia Hardes, et al. · Bioorganic & Medicinal Chemistry Letters · 28
The Antiviral Potential of Host Protease Inhibitors
2018 · Torsten Steinmetzer, Kornelia Hardes · Springer eBooks · 26
Synthesis and Functional Characterization of Tridegin and Its Analogues: Inhibitors and Substrates of Factor XIIIa
2011 · Miriam Böhm, Toni Kühl, et al. · ChemMedChem · 26
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
2017 · Kornelia Hardes, Teodora Ivanova, et al. · ChemMedChem · 24
RNA interference to combat the Asian tiger mosquito in Europe: A pathway from design of an innovative vector control tool to its application
2023 · Ruth Müller, Miklós Bálint, et al. · Biotechnology Advances · 21
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Proteogenomics-guided functional venomics resolves the toxin arsenal and activity of Deinagkistrodon acutus venom
2024 · Ignazio Avella, Lennart Schulte, et al. · International Journal of Biological Macromolecules · 19
Novel Insights into Structure and Function of Factor XIIIa-Inhibitor Tridegin
2014 · Miriam Böhm, Charlotte A. Bäuml, et al. · Journal of Medicinal Chemistry · 19
Bioactivity Profiling of In Silico Predicted Linear Toxins from the Ants Myrmica rubra and Myrmica ruginodis
2022 · Sabine Hurka, Tim Lüddecke, et al. · Toxins · 17
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Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus
2018 · Nadine Krüger, Christian Sauder, et al. · Cell Reports · 17
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Phylogeny-guided discovery of a promiscuous P450 macrocyclase for the production of diverse atropopeptides
2025 · Bin Tan, Peter Breunig, et al. · Chemical Science · 16
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Functional Profiling of the A-Family of Venom Peptides from the Wolf Spider Lycosa shansia
2023 · Tim Lüddecke, Ludwig Dersch, et al. · Toxins · 16
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Works count: 80
Citation count: 2,086
H-index: 19
I10-index: 27
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