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Robert Hettle
Observed names:
Hettle, Robert,
R Hettle,
R. Hettle
Institution:
AstraZeneca (United Kingdom)
Observed institutions:
AstraZeneca (United Kingdom),
PAREXEL International (United Kingdom),
AstraZeneca (United States),
University of York
ORCID:
0000-0002-1100-1266
Observed ORCID:
0000-0002-1100-1266
OpenAlex ID:
A5080315218
The assessment and appraisal of regenerative medicines and cell therapy products: an exploration of methods for review, economic evaluation and appraisal
2017
·
Robert Hettle
, Mark Corbett
, et al.
·
Health Technology Assessment
·
126
PDF
Patient-reported outcomes in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer receiving olaparib versus chemotherapy in the OlympiAD trial
2019
·
Mark Robson
, Kathryn J. Ruddy
, et al.
·
European Journal of Cancer
·
86
Systematic literature review and network meta-analysis of cladribine tablets versus alternative disease-modifying treatments for relapsing–remitting multiple sclerosis
2017
·
Mohd Kashif Siddiqui
, Inderpreet Singh Khurana
, et al.
·
Current Medical Research and Opinion
·
86
PDF
Patient-centred outcomes and effect of disease progression on health status in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation receiving maintenance olaparib or placebo (SOLO1): a randomised, phase 3 trial
2021
·
Michael Friedlander
, Kathleen N Moore
, et al.
·
The Lancet Oncology
·
58
Cost-Effectiveness of Adding Bedaquiline to Drug Regimens for the Treatment of Multidrug-Resistant Tuberculosis in the UK
2015
·
Lara J. Wolfson
, Anna Walker
, et al.
·
PLoS ONE
·
49
PDF
Cost-effectiveness of cladribine tablets, alemtuzumab, and natalizumab in the treatment of relapsing-remitting multiple sclerosis with high disease activity in England
2018
·
Robert Hettle
, Gerard Harty
, et al.
·
Journal of Medical Economics
·
43
Population-adjusted indirect treatment comparison of the SOLO1 and PAOLA-1/ENGOT-ov25 trials evaluating maintenance olaparib or bevacizumab or the combination of both in newly diagnosed, advanced BRCA-mutated ovarian cancer
2021
·
Ignace Vergote
, Isabelle Ray-Coquard
, et al.
·
European Journal of Cancer
·
30
Real-world treatment patterns and outcomes in small-cell lung cancer: a systematic literature review
2021
·
Sukhvinder Johal
, Robert Hettle
, et al.
·
Journal of Thoracic Disease
·
29
PDF
Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany
2017
·
Daniel Wirth
, Ramesh Dass
, et al.
·
BMC Health Services Research
·
25
PDF
Cost-utility analysis of tiotropium versus usual care in patients with COPD in the UK and Belgium
2012
·
Robert Hettle
, Hanne Wouters
, et al.
·
Respiratory Medicine
·
25
Cost-effectiveness of olaparib as a maintenance treatment for women with newly diagnosed advanced ovarian cancer and BRCA1/2 mutations in the United States
2020
·
Dominic Muston
, Robert Hettle
, et al.
·
Gynecologic Oncology
·
21
Survival Extrapolation Incorporating General Population Mortality Using Excess Hazard and Cure Models: A Tutorial
2023
·
Michael J. Sweeting
, Mark J. Rutherford
, et al.
·
Medical Decision Making
·
20
PDF
Cost-effectiveness of bedaquiline in MDR and XDR tuberculosis in Italy
2017
·
Luigi R. Codecasa
, Mondher Toumi
, et al.
·
Journal of Market Access & Health Policy
·
18
An economic evaluation based on a randomized placebo-controlled trial of varenicline in smokers with cardiovascular disease: results for Belgium, Spain, Portugal, and Italy
2011
·
Koo Wilson
, Robert Hettle
, et al.
·
European Journal of Preventive Cardiology
·
16
A matching‐adjusted indirect comparison of acalabrutinib versus zanubrutinib in relapsed or refractory chronic lymphocytic leukemia
2023
·
Adam S. Kittai
, Alan Skarbnik
, et al.
·
American Journal of Hematology
·
14
Indirect treatment comparison of olaparib and talazoparib in germline BRCA-mutated HER2-negative metastatic breast cancer
2021
·
Charles McCrea
, Robert Hettle
, et al.
·
Journal of Comparative Effectiveness Research
·
12
Population-adjusted indirect treatment comparison of maintenance PARP inhibitor with or without bevacizumab versus bevacizumab alone in women with newly diagnosed advanced ovarian cancer
2021
·
Robert Hettle
, Charles McCrea
, et al.
·
Therapeutic Advances in Medical Oncology
·
12
Exploring the Impact of Treatment Switching on Overall Survival from the PROfound Study in Homologous Recombination Repair (HRR)-Mutated Metastatic Castration-Resistant Prostate Cancer (mCRPC)
2021
·
Rachel Evans
, Neil Hawkins
, et al.
·
Targeted Oncology
·
11
PDF
Population adjusted indirect comparison of the SOLO1 and PAOLA-1/ENGOT-ov25 studies of olaparib with or without bevacizumab, bev alone and placebo in the maintenance treatment of women with newly diagnosed stage III/IV ovarian cancer with BRCA mutation
2020
·
I.B. Vergote
, K.N. Moore
, et al.
·
Gynecologic Oncology
·
11
Estimating health-state utility values for patients with recurrent ovarian cancer using Functional Assessment of Cancer Therapy – General mapping algorithms
2015
·
Robert Hettle
, John Borrill
, et al.
·
ClinicoEconomics and Outcomes Research
·
11
PDF
Challenges in economic modeling of anticancer therapies: an example of modeling the survival benefit of olaparib maintenance therapy for patients with BRCA-mutated platinum-sensitive relapsed ovarian cancer
2015
·
Robert Hettle
, John Posnett
, et al.
·
Journal of Medical Economics
·
11
PDF
Patient‐centered outcomes in the POLO study of active maintenance olaparib for germline BRCA‐mutated metastatic pancreatic cancer
2023
·
Hedy L. Kindler
, Hyun Kyoo Yoo
, et al.
·
Cancer
·
9
PDF
Cost-effectiveness of olaparib versus routine surveillance in the maintenance setting for patients withBRCA-mutated advanced ovarian cancer after response to first-line platinum-based chemotherapy in Singapore
2021
·
David SP Tan
, Jack Junjie Chan
, et al.
·
Journal of Gynecologic Oncology
·
9
Indirect treatment comparison of the efficacy and safety of olaparib 300 mg tablets BID and talazoparib 1 mg once daily in the treatment of patients with germline BRCA-mutated (gBRCA) HER2-negative metastatic breast cancer.
2019
·
Charles McCrea
, Robert Hettle
·
Journal of Clinical Oncology
·
9
Budget impact of including ribociclib in combination with letrozole on US payer formulary: first-line treatment of post-menopausal women with HR+/HER2− advanced or metastatic breast cancer
2018
·
Rohit Mistry
, Gaurav Suri
, et al.
·
Current Medical Research and Opinion
·
9
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Works count:
111
Citation count:
861
H-index:
14
I10-index:
21
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