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Kei Takedomi

Classification of Chemical Compounds by Protein−Compound Docking for Use in Designing a Focused Library
2005 · Yoshifumi Fukunishi, Yoshiaki Mikami, et al. · Journal of Medicinal Chemistry · 42
Discovery of Novel Pyrazole-Based Selective Aldosterone Synthase (CYP11B2) Inhibitors: A New Template to Coordinate the Heme-Iron Motif of CYP11B2
2018 · Ryo Sakakibara, Wataru Sasaki, et al. · Journal of Medicinal Chemistry · 24
Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety
2019 · Yuuki Koizumi, Yoshihito Tanaka, et al. · Bioorganic & Medicinal Chemistry · 16
Combination of Virtual Screening and High Throughput Gene Profiling for Identification of Novel Liver X Receptor Modulators
2008 · Jie-Fei Cheng, James Zapf, et al. · Journal of Medicinal Chemistry · 14
Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor
2022 · Daisuke Iijima, Hiroshi Sugama, et al. · Journal of Medicinal Chemistry · 13
Discovery of Apararenone (MT-3995) as a Highly Selective, Potent, and Novel Nonsteroidal Mineralocorticoid Receptor Antagonist
2022 · Toru Iijima, Makoto Katoh, et al. · Journal of Medicinal Chemistry · 13
Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists
2007 · Farid Bakir, Sunil Kher, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor
2018 · Yoichi Kadoh, Haruko Miyoshi, et al. · Chemical and Pharmaceutical Bulletin · 10
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Prediction of the binding affinity of compounds with diverse scaffolds by MP-CAFEE
2013 · Okimasa Okada, Hiroshi Yamashita, et al. · Biophysical Chemistry · 5
Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors
2022 · Daisuke Iijima, Hiroshi Sugama, et al. · ACS Medicinal Chemistry Letters · 3
Effect of Water Molecules on the Activating S810L Mutation of the Mineralocorticoid Receptor
2021 · Kei Takedomi, Masateru Ohta, et al. · Journal of Chemical Information and Modeling · 2
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Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies
2024 · Rima Matsuyama-Ito, Tomoharu Hogiri, et al. · Journal of Bioscience and Bioengineering
Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Highly Selective PDE10A Inhibitor
2019 · K. Takedomi, Y. Koizumi · Worldwide Protein Data Bank
Discovery of a Novel PDE10A Inhibitor as Highly Effective for Schizophrenia
2017 · Yoichi Kadoh, Takehiko Matsumura, et al. · 日本薬学会年会要旨集(CD-ROM)
Works count: 14
Citation count: 155
H-index: 8
I10-index: 8
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