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Manik Chatterjee

Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma
2021 · Matteo C. Da Vià, Oliver Dietrich, et al. · Nature Medicine · 327
Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells
2004 · Franziska Jundt, Kristina Schulze Pröbsting, et al. · Blood · 217
Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma
2005 · Thorsten Stühmer, Manik Chatterjee, et al. · Blood · 180
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The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma
2012 · M. Chatterjee, M. Andrulis, et al. · Haematologica · 162
Pasotuxizumab, a Bite ® Immune Therapy for Castration-Resistant Prostate Cancer: Phase I, Dose-Escalation Study Findings
2020 · Horst-Dieter Hummel, Peter Kufer, et al. · Immunotherapy · 153
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STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90α and β in multiple myeloma cells, which critically contribute to tumor-cell survival
2006 · Manik Chatterjee, Sarika Jain, et al. · Blood · 144
PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells
2004 · S Lentzsch, M Chatterjee, et al. · Leukemia · 127
Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells
2004 · Manik Chatterjee, Thorsten Stühmer, et al. · Blood · 124
Spectrum and functional validation of PSMB5 mutations in multiple myeloma
2018 · Santiago Barrio, Thorsten Stühmer, et al. · Leukemia · 123
Phase I study of the heparanase inhibitor roneparstat: an innovative approach for ultiple myeloma therapy
2018 · Monica Galli, Manik Chatterjee, et al. · Haematologica · 117
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The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma
2007 · Manik Chatterjee, Christoph Rancso, et al. · Blood · 109
In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway
2002 · Manik Chatterjee, Dirk Hönemann, et al. · Blood · 100
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Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction
2010 · L Stingl, T Stühmer, et al. · British Journal of Cancer · 94
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GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6
2015 · L. Rasche, J. Duell, et al. · Haematologica · 92
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Long-term outcome of patients with relapsed/refractory B-cell non-Hodgkin lymphoma treated with blinatumomab
2019 · Vera Dufner, Cyrus M. Sayehli, et al. · Blood Advances · 91
Signalling profile and antitumour activity of the novel Hsp90 inhibitor NVP-AUY922 in multiple myeloma
2008 · T Stühmer, A Zöllinger, et al. · Leukemia · 86
MOR202, a novel anti-CD38 monoclonal antibody, in patients with relapsed or refractory multiple myeloma: a first-in-human, multicentre, phase 1–2a trial
2020 · Marc S Raab, Monika Engelhardt, et al. · The Lancet Haematology · 82
Mutated RAS and constitutively activated Akt delineate distinct oncogenic pathways, which independently contribute to multiple myeloma cell survival
2010 · Torsten Steinbrunn, Thorsten Stühmer, et al. · Blood · 81
CXCL 12 and CXCR 7 are relevant targets to reverse cell adhesion‐mediated drug resistance in multiple myeloma
2017 · Johannes M. Waldschmidt, Anna Simon, et al. · British Journal of Haematology · 78
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells
2011 · U-M Fagerli, K Ullrich, et al. · Oncogene · 74
Autologous T cell therapy for PRAME+ advanced solid tumors in HLA-A*02+ patients: a phase 1 trial
2025 · Martin Wermke, Dejka M. Araujo, et al. · Nature Medicine · 70
Combined functional and molecular analysis of tumor cell signaling defines 2 distinct myeloma subgroups: Akt-dependent and Akt-independent multiple myeloma
2008 · Angela Zöllinger, Thorsten Stühmer, et al. · Blood · 69
Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines
2017 · Jun Li, Raina Seupel, et al. · Journal of Natural Products · 68
The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78
2013 · Leo Rasche, Johannes Duell, et al. · PLoS ONE · 67
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The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma
2012 · Tanja Heimberger, Mindaugas Andrulis, et al. · British Journal of Haematology · 66
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Works count: 125
Citation count: 4,206
H-index: 38
I10-index: 65
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