Author

Marty A. Fernandez

Observed names: Marty A Fernandez, Marty Fernandez

Institution: Brigham and Women's Hospital

Observed institutions: Brigham and Women's Hospital, Harvard University, University of Florida Health, University of Florida

ORCID: 0000-0002-3211-2563

Observed ORCID: 0000-0002-3211-2563

OpenAlex ID: A5080940283

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

2021 · Valentina N. Lagomarsino, Richard V. Pearse, et al. · Neuron · 149

Alzheimer Presenilin-1 Mutations Dramatically Reduce Trimming of Long Amyloid β-Peptides (Aβ) by γ-Secretase to Increase 42-to-40-Residue Aβ

2014 · Marty A. Fernandez, Julia A. Klutkowski, et al. · Journal of Biological Chemistry · 135

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Dissociation between the Processivity and Total Activity of γ-Secretase: Implications for the Mechanism of Alzheimer's Disease-Causing Presenilin Mutations

2011 · Omar Quintero-Monzon, Morgan M. Martin, et al. · Biochemistry · 117

Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

2017 · Christina R. Muratore, Constance Zhou, et al. · Stem Cell Reports · 85

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The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease

2007 · Roxana M. Coman, Arthur H. Robbins, et al. · Biochemistry · 46

Transmembrane Substrate Determinants for γ-Secretase Processing of APP CTFβ

2016 · Marty A. Fernandez, Kelly M. Biette, et al. · Biochemistry · 41

Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brain

2021 · YouJin Lee, Morgan R Miller, et al. · Brain · 35

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Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes

2010 · Arthur H. Robbins, Roxana M. Coman, et al. · Acta Crystallographica Section D Biological Crystallography · 29

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Disruption of amyloid precursor protein ubiquitination selectively increases amyloid β (Aβ) 40 levels via presenilin 2-mediated cleavage

2017 · Rebecca L. Williamson, Karine Laulagnier, et al. · Journal of Biological Chemistry · 28

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A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer’s disease

2023 · Liviu Aron, Chenxi Qiu, et al. · Nature Communications · 22

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Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neurons

2022 · Marty A. Fernandez, Fatmata Bah, et al. · Stem Cell Reports · 19

Sequential Proteolysis by γ-Secretase and Its Implications for Alzheimer’s Disease

2015 · Marty A. Fernandez · Digital Access to Scholarship at Harvard (DASH) (Harvard University) · 2

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Early lysosome defects precede neurodegeneration with Aβ and tau aggregation

2022 · Eugene Lee, Morgan Miller, et al. · Alzheimer s & Dementia

P1‐082: Investigation of substrate determinants for proteolysis of app ctfβ by gamma‐secretase

2015 · Marty A. Fernandez, Michael S. Wolfe · Alzheimer s & Dementia

O1–08–01: Dual‐pathway carboxypeptidase activity is an intrinsic property of gamma‐secretase

2013 · Marty Fernandez, Michael Wolfe · Alzheimer s & Dementia

P3–072: Gamma‐secretase trims ε‐cleaved products to beta‐amyloid 40 and beta‐amyloid 42 via two main pathways

2013 · Marty Fernandez, Michael Wolfe · Alzheimer s & Dementia

Characterization of HIV‐1 subtype C I50V and I50L proteases

2009 · Edith Rosvely Bracho‐Sanchez, Marty Fernandez, et al. · The FASEB Journal

Works count: 17

Citation count: 708

H-index: 11

I10-index: 11