Author

Jasvinder K. Atwal

Observed names: Atwal, Jasvinder, Atwal, Jasvinder K., J Atwal, J. K. Atwal, Jasvinder Atwal, Jasvinder K Atwal

Observed institutions: Boston Children's Hospital, Montreal Neurological Institute and Hospital, Roche (United States), Salk Institute for Biological Studies, Howard Hughes Medical Institute, Harvard University, Genentech, University of Toronto, University of California, Irvine, Hospital for Sick Children, Array BioPharma (United States), Stanford Medicine, McGill University, Stanford University

ORCID: 0000-0001-5995-478X

Observed ORCID: 0000-0001-5995-478X

OpenAlex ID: A5081034755

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

2012 · Thorlakur Jonsson, Jasvinder K. Atwal, et al. · Nature · 1,739

Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

2011 · Y. Joy Yu, Yin Zhang, et al. · Science Translational Medicine · 788

Biosynthesis and Post-translational Processing of the Precursor to Brain-derived Neurotrophic Factor

2001 · S. Javad Mowla, Hooman F. Farhadi, et al. · Journal of Biological Chemistry · 571

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

2008 · Jasvinder K. Atwal, Julie Pinkston-Gosse, et al. · Science · 502

The TrkB-Shc Site Signals Neuronal Survival and Local Axon Growth via MEK and PI3-Kinase

2000 · Jasvinder K Atwal, Bernard Massie, et al. · Neuron · 435

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Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

2014 · Y. Joy Yu, Jasvinder K. Atwal, et al. · Science Translational Medicine · 369

EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans

2005 · Vuk Koprivica, Kin-Sang Cho, et al. · Science · 363

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

2017 · Megan Lo, Hok Seon Kim, et al. · Journal of Biological Chemistry · 324

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An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A Binding Properties Promotes Neuroprotection and Glial Engulfment of A

2012 · O. Adolfsson, M. Pihlgren, et al. · Journal of Neuroscience · 317

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P53 Is Essential for Developmental Neuron Death as Regulated by the TrkA and p75 Neurotrophin Receptors

1998 · Raquel S. Aloyz, Shernaz X. Bamji, et al. · The Journal of Cell Biology · 302

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A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo

2011 · Jasvinder K. Atwal, Yongmei Chen, et al. · Science Translational Medicine · 273

Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

2005 · Binhai Zheng, Jasvinder Atwal, et al. · Proceedings of the National Academy of Sciences · 269

Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein

2014 · Janice A. Maloney, Travis Bainbridge, et al. · Journal of Biological Chemistry · 197

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

2014 · Monica K Wetzel-Smith, Julie Hunkapiller, et al. · Nature Medicine · 153

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

2016 · Seung-Hye Lee, Claire E. Le Pichon, et al. · Cell Reports · 126

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Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons.

1996 · R S Slack, D J Belliveau, et al. · The Journal of Cell Biology · 124

Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin

2016 · Mark Ultsch, Bing Li, et al. · Scientific Reports · 123

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Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease

2021 · Gai Ayalon, Seung-Hye Lee, et al. · Science Translational Medicine · 110

P63 Is an Essential Proapoptotic Protein during Neural Development

2005 · W. Bradley Jacobs, Gregory Govoni, et al. · Neuron · 104

Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse

2003 · Jasvinder K. Atwal, Karun K. Singh, et al. · Journal of Neuroscience · 104

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A Therapeutic Antibody Targeting Bace1 Inhibits Amyloid-beta Production in Vivo

2013 · Jasvinder K. Atwal, Y. Chen, et al. · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · 56

Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain

2016 · Kapil Gadkar, Daniela Bumbaca Yadav, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 51

Widespread brain distribution and activity following i.c.v. infusion of anti‐β‐secretase (BACE1) in nonhuman primates

2017 · Daniela Bumbaca Yadav, Janice A Maloney, et al. · British Journal of Pharmacology · 49

Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ

2019 · William J. Meilandt, Janice A. Maloney, et al. · Alzheimer s Research & Therapy · 45

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Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid

2022 · Shraddha S. Sadekar, Mayumi Bowen, et al. · Clinical Pharmacology & Therapeutics · 43

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Works count: 55

Citation count: 7,677

H-index: 26

I10-index: 30