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Hiroyuki Hanzawa
Observed names:
H Hanzawa,
H. HANZAWA,
H. Hanzawa,
Hanzawa, Hiroyuki,
Hiroyuki HANZAWA,
半沢, 宏之
show all 6
Institution:
Daiichi Sankyo RD Novare (Japan)
Observed institutions:
Utrecht University,
Nagoya City University,
Daiichi-Sankyo (Japan),
Sanwa Kagaku Kenkyusho Co., Ltd. (Japan),
Daiichi Sankyo RD Novare (Japan),
The University of Tokyo
show all 6
ORCID:
0000-0002-0471-7936
Observed ORCID:
0000-0002-0471-7936
OpenAlex ID:
A5081118215
Identification of a ubiquitin–protein ligase subunit within the CCR4–NOT transcription repressor complex
2002
·
Thomas K. Albert
, Hiroyuki Hanzawa
, et al.
·
The EMBO Journal
·
219
Phomactin A; a novel PAF antagonist from a marine fungus Phoma sp
1991
·
Michihiro Sugano
, Aiya Sato
, et al.
·
Journal of the American Chemical Society
·
163
The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models
2019
·
Ryohei Katayama
, Bo Gong
, et al.
·
Nature Communications
·
151
PDF
Molecular Mechanism Underlying Inverse Agonist of Angiotensin II Type 1 Receptor
2006
·
Shin-ichiro Miura
, Masahiro Fujino
, et al.
·
Journal of Biological Chemistry
·
128
U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors
2020
·
Kyriakos P. Papadopoulos
, Erkut Borazanci
, et al.
·
Clinical Cancer Research
·
120
1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin
1990
·
Hiroyuki Hanzawa
, Ichio Shimada
, et al.
·
FEBS Letters
·
96
PDF
The Structure of the C4C4RING Finger of Human NOT4 Reveals Features Distinct from Those of C3HC4 RING Fingers
2001
·
Hiroyuki Hanzawa
, Marjolein J. de Ruwe
, et al.
·
Journal of Biological Chemistry
·
95
PDF
Structural study of asparagine-linked oligosaccharide moiety of taste-modifying protein, miraculin.
1990
·
N Takahashi
, H Hitotsuya
, et al.
·
Journal of Biological Chemistry
·
63
Structure and biosynthesis of the xylose‐containing carbohydrate moiety of rice α‐amylase
1990
·
Makoto HAYASHI
, Akiko TSURU
, et al.
·
European Journal of Biochemistry
·
55
PDF
Characterization of a functional domain of human calpastatin
1990
·
Takashi Uemori
, Tomoko Shimojo
, et al.
·
Biochemical and Biophysical Research Communications
·
51
Structural elucidation of a variety of GalNAc-containing N-linked oligosaccharides from human urinary kallidinogenase.
1993
·
N. Tomiya
, J. Awaya
, et al.
·
Journal of Biological Chemistry
·
50
Aldose reductase inhibitors from a marine sponge, Dictyodendrilla sp.
1993
·
Aiya Sato
, Tadaaki Morishita
, et al.
·
The Journal of Organic Chemistry
·
45
Crystal structure of the mineralocorticoid receptor ligand‐binding domain in complex with a potent and selective nonsteroidal blocker, esaxerenone (CS‐3150)
2020
·
Mizuki Takahashi
, Osamu Ubukata
, et al.
·
FEBS Letters
·
40
PDF
Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
2019
·
Naoki Nakao
, Masaharu Ueno
, et al.
·
Communications Chemistry
·
36
PDF
Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium
2020
·
Yumiko Mizukoshi
, Koh Takeuchi
, et al.
·
Science Advances
·
32
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
2017
·
Yumi Matsui
, Isao Yasumatsu
, et al.
·
Bioorganic & Medicinal Chemistry
·
31
An Accurate Pharmacophore Mapping Method by NMR Spectroscopy
2011
·
Yumiko Mizukoshi
, Aya Abe
, et al.
·
Angewandte Chemie International Edition
·
31
Small Molecules with Similar Structures Exhibit Agonist, Neutral Antagonist or Inverse Agonist Activity toward Angiotensin II Type 1 Receptor
2012
·
Shin-ichiro Miura
, Yoshihiro Kiya
, et al.
·
PLoS ONE
·
28
PDF
Synthesis of a tetrahydropyrano[2,3-d]oxazole analogue of trehazolin
1996
·
Masao Shiozaki
, Takashi Mochizuki
, et al.
·
Carbohydrate Research
·
27
Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity
2019
·
René Bartz
, Keisuke Fukuchi
, et al.
·
Molecular Cancer Therapeutics
·
24
PDF
Synthesis of a 2-Aminohexahydrobenzoxazole Analog Related to Trehazolin
1995
·
Hideki Miyazaki
, Yoshiyuki Kobayashi
, et al.
·
The Journal of Organic Chemistry
·
22
Analysis of fluoroquinolone-resistance using MIC determination and homology modelling of ParC of contemporary Mycoplasma genitalium strains
2021
·
Ryoichi Hamasuna
, Hiroyuki Hanzawa
, et al.
·
Journal of Infection and Chemotherapy
·
20
A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1
2018
·
Yumi Matsui
, Isao Yasumatsu
, et al.
·
Acta Crystallographica Section F Structural Biology Communications
·
18
PDF
Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
2015
·
Yumi Matsui
, Takahiro Yamaguchi
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
17
Proton nuclear magnetic resonance study of human interleukin 6: Chemical modifications and partial spectral assignments for the aromatic residues
1990
·
Chiaki Nishimura
, Hiroyuki Hanzawa
, et al.
·
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
·
17
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Works count:
85
Citation count:
1,721
H-index:
21
I10-index:
32
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