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Siew Lee Cheong

Observed names: Cheong, Siew Lee, S.L. Cheong, Siew Cheong, Siew L. Cheong
Institution: IMU University
ORCID: 0000-0001-6922-6540
Observed ORCID: 0000-0001-6922-6540
OpenAlex ID: A5081126201
Current Pharmacotherapy and Multi-Target Approaches for Alzheimer’s Disease
2022 · Siew Lee Cheong, Jian Kai Tiew, et al. · Pharmaceuticals · 95
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Current progress in antimalarial pharmacotherapy and multi-target drug discovery
2019 · Natasha Stella Tibon, Chew Hee Ng, et al. · European Journal of Medicinal Chemistry · 82
The current status of pharmacotherapy for the treatment of Parkinson’s disease: transition from single-target to multitarget therapy
2019 · Siew L. Cheong, Stephanie Federico, et al. · Drug Discovery Today · 76
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Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases
2022 · Yoke Chan Chow, Hok Chai Yam, et al. · Frontiers in Cellular and Infection Microbiology · 60
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Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment
2018 · Yi-Ming Shao, Xiaohua Ma, et al. · PLoS ONE · 49
The A3adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches
2011 · Siew Lee Cheong, Stephanie Federico, et al. · Medicinal Research Reviews · 48
The Significance of 2-Furyl Ring Substitution with a 2-(para-substituted) Aryl Group in a New Series of Pyrazolo-triazolo-pyrimidines as Potent and Highly Selective hA3Adenosine Receptors Antagonists: New Insights into Structure−Affinity Relationship and Receptor−Antagonist Recognition
2010 · Siew Lee Cheong, Anna Dolzhenko, et al. · Journal of Medicinal Chemistry · 41
Synthesis and Biological Evaluation of a New Series of 1,2,4-Triazolo[1,5-a]-1,3,5-triazines as Human A2AAdenosine Receptor Antagonists with Improved Water Solubility
2011 · Stephanie Federico, Silvia Paoletta, et al. · Journal of Medicinal Chemistry · 35
Design, Synthesis and Characterisation of Novel Phenothiazine‐Based Triazolopyridine Derivatives: Evaluation of Anti‐Breast Cancer Activity on Human Breast Carcinoma
2019 · Tanisha Sachdeva, May Lee Low, et al. · ChemistrySelect · 24
Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
2014 · Gopalakrishnan Venkatesan, Priyankar Paira, et al. · Bioorganic & Medicinal Chemistry · 20
Organoruthenium Antagonists of Human A3 Adenosine Receptors
2013 · Priyankar Paira, Mun Juinn Chow, et al. · Chemistry - A European Journal · 16
Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists
2011 · Siew Lee Cheong, Stephanie Federico, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Pyrazolo Derivatives as Potent Adenosine Receptor Antagonists: An Overview on the Structure-Activity Relationships
2011 · Siew Lee Cheong, Gopalakrishnan Venkatesan, et al. · International Journal of Medicinal Chemistry · 13
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Does the combination of optimal substitutions at the C2-, N5- and N8-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors?
2011 · Siew Lee Cheong, Anton V. Dolzhenko, et al. · Bioorganic & Medicinal Chemistry · 12
Inhibition of Porphyromonas gingivalis peptidyl arginine deiminase, a virulence factor, by antioxidant-rich Cratoxylum cochinchinense: In vitro and in silico evaluation
2021 · Sheri-Ann Tan, Hok Chai Yam, et al. · Saudi Journal of Biological Sciences · 11
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A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
2015 · G. Venkatesan, P. Paira, et al. · European Journal of Medicinal Chemistry · 8
Novel Cu(II) Schiff Base Complex Combination with Polymyxin B/Phenylalanine-Arginine β-Naphthylamide Against Various Bacterial Strains
2022 · Wei Khang Gan, Hui Shan Liew, et al. · International Journal of Peptide Research and Therapeutics · 4
Pharmacological relationships and ligand discovery of G protein-coupled receptors revealed by simultaneous ligand and receptor clustering
2017 · Cheng Zhang, Yi-Ming Shao, et al. · Journal of Molecular Graphics and Modelling · 3
Synthesis, in vitro antimalarial activity, cytotoxicity, and pharmacokinetic evaluation of chalcone-derived thiosemicarbazones
2026 · Sheng Zhou Ho, Ming Yueh Tan, et al. · Pure and Applied Chemistry · 1
Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy
2019 · Aaron Tan, Maria V. Babak, et al. · Molecules · 1
Cellular antioxidative and regenerative potentials of Clinacanthus nutans leaf fractions towards liver cells: An integrated in vitro and in silico study
2025 · Kai Song Ng, Siew Lee Cheong, et al. · ScienceAsia
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Inhibitory activity of mangiferin against Porphyromonas gingivalis gingipain K, a causal agent of Alzheimer?s disease: An integrated in vitro and in silico study
2024 · Sheri-Ann Tan, Jia Hui Lai, et al. · ScienceAsia
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Chapter 1: A3 adenosine receptor ligands in the treatment of inflammation and cancer
2016 · Siew Lee Cheong, Stephanie Federico, et al. · ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)
CCDC 937929: Experimental Crystal Structure Determination
2014 · Venkatesan, Gopalakrishnan, Paira, Priyankar, et al. · The Cambridge Structural Database
CCDC 900859: Experimental Crystal Structure Determination
2013 · Paira, Priyankar, Chow, Mun Juinn, et al. · The Cambridge Structural Database
Works count: 29
Citation count: 612
H-index: 13
I10-index: 15
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