Author

Scott Layzell

Observed names: Layzell, Scott, Layzell, Scott James, S Layzell, Scott J. Layzell

Institutions: Institute of Cancer Research, Breast Cancer Now

Observed institutions: Institute of Cancer Research, Breast Cancer Now, The Royal Free Hospital, John Radcliffe Hospital, University of Oxford, NIHR Oxford Biomedical Research Centre, University College London

ORCID: 0000-0002-6526-4061

Observed ORCID: 0000-0002-6526-4061

OpenAlex ID: A5081268631

A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

2024 · Jonathan Mannion, Valentina Gifford, et al. · Immunity · 93

NF-κB and Extrinsic Cell Death Pathways – Entwined Do-or-Die Decisions for T cells

2020 · Sam Blanchett, Ines Boal-Carvalho, et al. · Trends in Immunology · 58

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Prevalence of Borrelia burgdorferi and Borrelia miyamotoi in questing Ixodes ricinus ticks from four sites in the UK

2017 · Scott J. Layzell, Daniel Bailey, et al. · Ticks and Tick-borne Diseases · 18

IKK promotes naïve T cell survival by repressing RIPK1-dependent apoptosis and activating NF-κB

2023 · Fiona Carty, Scott Layzell, et al. · Science Signaling · 11

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NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells

2024 · Scott Layzell, Alessandro Barbarulo, et al. · Cell Death and Differentiation · 6

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Effects of oncolytic immunotherapy with RP1 (vusolimogene oderparepvec) on immune cells mediate responsiveness to anti-PD-1 via STING-mediated interferon signaling

2026 · Victoria Roulstone, Joan Kyula, et al. · Journal for ImmunoTherapy of Cancer · 5

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Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy

2026 · Winnie Fernando, Jarama Clucas, et al. · Nature Communications · 3

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Evidence for a RIPK1-independent survival mechanism for CASPASE-8 in αβ T cells

2025 · Farjana Islam, Scott Layzell, et al. · Discovery Immunology · 1

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Correction: NF-κB regulated expression of A20 controls IKK dependent repression of RIPK1 induced cell death in activated T cells

2024 · Scott Layzell, Alessandro Barbarulo, et al. · Cell Death and Differentiation · 1

NF-κB dependent expression of A20 controls IKK repression of RIPK1 dependent cell death in activated T cells

2023 · Scott Layzell, Alessandro Barbarulo, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1

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IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial

2026 · Crescens Tiu, Wing Yau, et al. · Nature Communications

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Necroptosis in Both Tumour and Stromal Compartments Determines Responsiveness to Immunogenic Cell Death-based Immunotherapy

2026 · Fernando, Winnie, Clucas, Jarama, et al. · Zenodo (CERN European Organization for Nuclear Research)

IKK controls naive T cell survival by repressing RIPK1 dependent apoptosis and activation of NF-κB

2021 · Fiona Carty, Scott Layzell, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Epithelial Cell Regulation of Type 2 Cytokine Release by Peripheral Blood Mononuclear Cells

2020 · Amy Southern, Aurelia Gondrand, et al. · bioRxiv (Cold Spring Harbor Laboratory)

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S87 Regulation of type 2 cytokine release by epithelial cells: characterisation of soluble factor pathways and characterisation of potential mediators

2017 · A Southern, S Layzell, et al.

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P51 Lung epithelial cell inhibition of cytokine production by peripheral blood mononuclear cells and lung lymphocytes

2017 · S Layzell, A Southern, et al.

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Works count: 18

Citation count: 197

H-index: 5

I10-index: 4