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Author

Martin Hornberger

Aroma Evolution during Flower Opening in Rosa damascena Mill
1999 · Noriaki Oka, Hisayoshi Ohishi, et al. · Zeitschrift für Naturforschung C · 77
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Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists
2010 · Ulrich Abel, Thomas Schlüter, et al. · Bioorganic & Medicinal Chemistry Letters · 54
Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties
2016 · Olaf Kinzel, Christoph Steeneck, et al. · Bioorganic & Medicinal Chemistry Letters · 36
Discovery of Hydroxyamidine Based Inhibitors of IDO1 for Cancer Immunotherapy with Reduced Potential for Glucuronidation
2020 · Christoph Steeneck, Olaf Kinzel, et al. · ACS Medicinal Chemistry Letters · 20
Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors
2020 · Christoph Steeneck, Olaf Kinzel, et al. · Bioorganic & Medicinal Chemistry Letters · 19
The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine‐rich glycoprotein
2014 · Ulrich Deuschle, Manfred Birkel, et al. · International Journal of Cancer · 19
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Purification and characterisation of the cardenolide-specificβ-glucohydrolase CGH II from Digitalis lanata leaves
2000 · Martin Hornberger, Ute Böttigheimer, et al. · Plant Physiology and Biochemistry · 12
Discovery of highly potent heme-displacing IDO1 inhibitors based on a spirofused bicyclic scaffold
2020 · Olaf Kinzel, Christoph Steeneck, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Development of Cilofexor, an Intestinally-Biased Farnesoid X Receptor Agonist, for the Treatment of Fatty Liver Disease
2024 · David Hollenback, Eva Hambruch, et al. · Journal of Pharmacology and Experimental Therapeutics · 9
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Structure-Specificity Relationship of Cardiac Glycosides as a Substrate for Glucohydrolase II.
2000 · Yukimasa TERADA, Rumi MISOI, et al. · Chemical and Pharmaceutical Bulletin · 3
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FRI-303-How to develop a differentiated FXR agonist: GS-9674 shows a reduced side effect profile in mice, monkeys amd human phase 1 studies compared to its predecessor Px-102
2019 · Eva Hambruch, David Hollenback, et al. · Journal of Hepatology · 2
From Mice to Men – Changes in FGF15/19 Expression and Bile Acid Levels as Sensitive Markers of Pharmacological FXR Activation; Results from Human Phase I and Animal Studies Using the Potent and Selective FXR Agonist Px-102
2016 · E. Hambruch, H. Krol, et al. · Journal of Hepatology
Works count: 12
Citation count: 261
H-index: 9
I10-index: 8
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