Author

Kevin J. Leco

Observed names: K J Leco, K LECO, K. J. Leco, K. Leco, K.J. Leco, KJ Leco, Kevin J Leco, Kevin J. LECO, Kevin Leco, Leco KJ

Institution: Western University

Observed institutions: Western University, BC Cancer Agency, Lawson Health Research Institute, University Health Network, University of Wisconsin–Madison, University of Calgary, University of Toronto, Princess Margaret Cancer Centre, University of Chicago, University of Wisconsin Carbone Cancer Center, University of Manitoba

OpenAlex ID: A5081445796

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

1994 · K.J. Leco, R. Khokha, et al. · Journal of Biological Chemistry · 480

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

1999 · P A Forsyth, H Wong, et al. · British Journal of Cancer · 436

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Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene

1993 · Paul S. Rennie, Nicholas Bruchovsky, et al. · Molecular Endocrinology · 323

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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

2001 · Kevin J. Leco, Paul Waterhouse, et al. · Journal of Clinical Investigation · 246

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

2001 · Kevin J. Leco, Paul Waterhouse, et al. · Journal of Clinical Investigation · 230

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Murine tissue inhibitor of metalloproteinases—4 (Timp—4): cDNA isolation and expression in adult mouse tissues1

1997 · Kevin J. Leco, Suneel S. Apte, et al. · FEBS Letters · 195

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Proteinase expression in early mouse embryos is regulated by leukaemia inhibitory factor and epidermal growth factor

1995 · M. B. Harvey, K. J. Leco, et al. · Development · 191

Accelerated apoptosis in the Timp-3–deficient mammary gland

2001 · Jimmie E. Fata, Kevin J. Leco, et al. · Journal of Clinical Investigation · 183

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TIMP-3 Deficiency Leads to Dilated Cardiomyopathy

2004 · Paul W.M. Fedak, David S. Smookler, et al. · Circulation · 181

Expression and Prognostic Significance of Metalloproteinases and Their Tissue Inhibitors in Patients With Small-Cell Lung Cancer

1999 · M. Michael, B. Babic, et al. · Journal of Clinical Oncology · 160

Cellular turnover and extracellular matrix remodeling in female reproductive tissues: functions of metalloproteinases and their inhibitors

2000 · J. E. Fata, A. T.-V. Ho, et al. · Cellular and Molecular Life Sciences · 151

Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas

1992 · SJ Urbanski, DR Edwards, et al. · British Journal of Cancer · 140

The roles of tissue inhibitors of metalloproteinases in tissue remodelling and cell growth.

1996 · D R Edwards, P P Beaudry, et al. · PubMed · 135

Timp-1 Is Important for Epithelial Proliferation and Branching Morphogenesis during Mouse Mammary Development

1999 · Jimmie E. Fata, Kevin J. Leco, et al. · Developmental Biology · 111

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Differential effects of transforming growth factor-β1 on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in young and old human fibroblasts

1996 · Dylan R. Edwards, Kevin J. Leco, et al. · Experimental Gerontology · 102

Endocrinology and paracrinology: Roles of growth factors during peri-implantation development

1995 · M.B. Harvey, K.J. Leco, et al. · Human Reproduction · 98

A null mutation for Tissue Inhibitor of Metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis

2003 · Sean E Gill, M.Cynthia Pape, et al. · Developmental Biology · 96

Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts

1992 · Kevin J. Leco, Lawrence J. Hayden, et al. · Gene · 93

Tissue inhibitor of metalloproteinases-3 is the major metalloproteinase inhibitor in the decidualizing murine uterus

1996 · Kevin J. Leco, Dylan R. Edwards, et al. · Molecular Reproduction and Development · 67

Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene

2002 · David A. YOUNG, Blaine W. PHILLIPS, et al. · Biochemical Journal · 65

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Tissue inhibitor of metalloproteinases 3 regulates extracellular matrix—Cell signaling during bronchiole branching morphogenesis

2006 · Sean E. Gill, M. Cynthia Pape, et al. · Developmental Biology · 59

Expression and Activity of Ovarian Tissue Inhibitors of Metalloproteinases during Pseudopregnancy in the Rat1

1995 · Warren B. Nothnick, Dylan R. Edwards, et al. · Biology of Reproduction · 56

Matrix metalloproteinases mediate the dismantling of mesenchymal structures in the tadpole tail during thyroid hormone‐induced tail resorption

2002 · Jae‐Chang Jung, Kevin J. Leco, et al. · Developmental Dynamics · 51

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Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis

2003 · Erica L. Martin, Brent Z. Moyer, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 44

Cloning of the Human Tissue Inhibitor of Metalloproteinase-4 Gene (TIMP4) and Localization of the TIMP4 andTimp4Genes to Human Chromosome 3p25 and Mouse Chromosome 6, Respectively

1998 · Timothy M. Olson, Satoshi Hirohata, et al. · Genomics · 33

Works count: 38

Citation count: 4,066

H-index: 26

I10-index: 31