Get started
Author

Akihito Ogasawara

Observed name: オガサワラ, アキヒト
ORCID: 0000-0002-1652-1711
Observed ORCID: 0000-0002-1652-1711
OpenAlex ID: A5081500668
Effect of Oral Ketoconazole on Intestinal First-Pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys
2006 · Akihito Ogasawara, Toshiyuki Kume, et al. · Drug Metabolism and Disposition · 55
Prediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in Animals
2018 · Hidetoshi Shimizu, Kosuke Yoshida, et al. · Drug Metabolism and Disposition · 27
PDF
Effect of Oral Ketoconazole on Oral and Intravenous Pharmacokinetics of Simvastatin and Its Acid in Cynomolgus Monkeys
2008 · Akihito Ogasawara, Masahiro Utoh, et al. · Drug Metabolism and Disposition · 18
In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
2009 · Akihito Ogasawara, Isao Negishi, et al. · Drug Metabolism and Disposition · 15
Results from a first-in-human study of dersimelagon, an investigational oral selective MC1R agonist
2023 · Akihito Ogasawara, Kei Ogawa, et al. · European Journal of Clinical Pharmacology · 9
PDF
Absorption, metabolism, and excretion of [ 14 C ]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers
2023 · Minoru Tsuda, Kei Ogawa, et al. · Pharmacology Research & Perspectives · 8
PDF
Discovery of MT-7117 (Dersimelagon Phosphoric Acid): A Novel, Potent, Selective, and Nonpeptidic Orally Available Melanocortin 1 Receptor Agonist
2024 · Atsushi Sato, Kenji Morokuma, et al. · Journal of Medicinal Chemistry · 6
The Oral Bioavailability and Effect of Various Gastric Conditions on the Pharmacokinetics of Dersimelagon in Healthy Adult Volunteers
2023 · Kei Ogawa, Ryosuke Ide, et al. · Clinical Pharmacology in Drug Development · 6
PDF
Effect of Hepatic and Renal Impairment on the Pharmacokinetics of Dersimelagon (MT‐7117), an Oral Melanocortin‐1 Receptor Agonist
2024 · Akihito Ogasawara, Ryosuke Ide, et al. · Clinical Pharmacology in Drug Development · 1
Assessment of Potential Drug–Drug Interactions for Novel Oral Melanocortin‐1 Receptor Agonist Dersimelagon
2025 · Akihito Ogasawara, Ryosuke Ide, et al. · Pharmacology Research & Perspectives
PDF
Physiologically based pharmacokinetic modelling to predict potential drug–drug interactions of dersimelagon (MT‐7117)
2024 · Akihito Ogasawara, Koki Kojima, et al. · British Journal of Clinical Pharmacology
PDF
Usefulness of an Animal Model Using Cynomolgus Monkeys for Prediction of Drug-drug Interaction in Humans
2011 · 小笠原, 明人, オガサワラ, アキヒト · Institutional Repositories DataBase (IRDB)
PDF
Works count: 12
Citation count: 145
H-index: 6
I10-index: 4
Year
Topic
Type