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Zhili Chang

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types
2017 · Yongqian Shu, Xue Wu, et al. · Scientific Reports · 223
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Causative Species and Serotypes of Shigellosis in Mainland China: Systematic Review and Meta-Analysis
2012 · Zhili Chang, Shuting Lu, et al. · PLoS ONE · 57
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G enetic and clonal dissection of osteosarcoma progression and lung metastasis
2018 · Huaiyuan Xu, Xiaojun Zhu, et al. · International Journal of Cancer · 52
Cell-Free DNA Provides a Good Representation of the Tumor Genome Despite Its Biased Fragmentation Patterns
2017 · Xiangyuan Ma, Liangjun Zhu, et al. · PLoS ONE · 36
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Circulating tumor DNA profiling by next generation sequencing reveals heterogeneity of crizotinib resistance mechanisms in a gastric cancer patient with MET amplification
2017 · Juan Du, Xue Wu, et al. · Oncotarget · 25
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Investigating novel resistance mechanisms to third generation EGFR TKI osimertinib in non-small cell lung cancer patients using next generation sequencing.
2017 · Qiuxiang Ou, Xue Wu, et al. · Journal of Clinical Oncology · 18
Capture‐based next‐generation sequencing reveals multiple actionable mutations in cancer patients failed in traditional testing
2016 · Jing Xie, Xiongxiong Lu, et al. · Molecular Genetics & Genomic Medicine · 16
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Influence of low tumor content on tumor mutational burden estimation by whole‐exome sequencing and targeted panel sequencing
2021 · Wenxin Zhang, Ruixia Wang, et al. · Clinical and Translational Medicine · 13
THOR: a TMB heterogeneity-adaptive optimization model predicts immunotherapy response using clonal genomic features in group-structured data
2024 · Yixuan Wang, Yanfang Guan, et al. · Briefings in Bioinformatics · 8
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TMBstable: a variant caller controls performance variation across heterogeneous sequencing samples
2024 · Shenjie Wang, Xiaoyan Zhu, et al. · Briefings in Bioinformatics · 5
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TMBocelot: an omnibus statistical control model optimizing the TMB thresholds with systematic measurement errors
2025 · Xin Lai, Shaoliang Wang, et al. · Frontiers in Immunology · 3
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TMBclaw: tumor clone-aware graph learning improves immunotherapy response prediction across heterogeneous cohorts
2025 · Yixuan Wang, Tianyi Zhu, et al. · Briefings in Bioinformatics · 2
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Toward generalizable prediction of cancer signal using a cell-free DNA language model
2026 · Yang Xu, Hua Bao, et al. · Cell Reports Medicine · 1
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PScnv: personalized self-normalizing CNV detection with a hierarchical multi-phase framework
2026 · Xuwen Wang, Zhili Chang, et al. · Bioinformatics · 1
TMBquant: an explainable AI-powered caller advancing tumor mutation burden quantification across heterogeneous samples
2025 · Shenjie Wang, Xiaonan Wang, et al. · Briefings in Bioinformatics · 1
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MRDadaptis: self-adaptive parameter configuration enhances minimal residual disease detection in heterogeneous ctDNA samples
2025 · Tianci Wang, Xin Lai, et al. · Briefings in Bioinformatics · 1
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EMcnv: enhancing CNV detection performance through ensemble strategies with heterogeneous meta-graph neural networks
2025 · Xuwen Wang, Zhili Chang, et al. · Briefings in Bioinformatics · 1
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MARM: a framework for malignancy risk prediction from host-derived CNV in bronchoalveolar lavage fluid mNGS data with microbial admixture
2026 · Zhili Chang, Xiaonan Wang, et al. · Frontiers in Microbiology
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Abstract 3852: Ultrasensitive AI-driven framework for MRD detection based on multidimensional cfDNA features.
2026 · Yunfei Shi, Hao Zhang, et al. · Cancer Research
CNV-Sculptor: A High-Fidelity Software for Precise Simulation of Tumor Copy Number Variations and Purity
2025 · Zhili Chang, Xiaonan Wang, et al. · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Abstract 5053: Targeted sequencing panel for comprehensive MTAP deletion detection in diverse cancer types
2025 · Hua Bao, Haimeng Tang, et al. · Cancer Research
Abstract 4561: ShieldingUltra: A novel approach for enhanced minimal residual disease detection through the integration of mutation, copy number variation, and fragmentomics
2025 · Hao Zhang, Ningyou Li, et al. · Cancer Research
Abstract 2403: Efficient detection of whole genome duplication: a targeted sequencing approach
2025 · Hua Bao, Haimeng Tang, et al. · Cancer Research
Abstract 5055: Efficient detection of chromosomal instability in diverse cancers using a targeted sequencing approach
2025 · Hua Bao, Rui Liu, et al. · Cancer Research
Correction of Read Biases Induced by Complex Reference Genome Regions for Improving Copy Number Variation Detection Using a Gaussian Mixture Model
2024 · Xuwen Wang, Zhili Chang, et al. · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Works count: 29
Citation count: 463
H-index: 8
I10-index: 8
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