Author

Philipp Thiel

Observed names: P. Thiel, Thiel, P., Thiel, Philipp

Observed institutions: University of Siena, Max Planck Society, Johannes Gutenberg University Mainz, AstraZeneca (Sweden), Chemical Genomics Centre, Quantitative Biology Center, Monash University, University of Tübingen, Saarland University

ORCID: 0000-0001-9498-1214

Observed ORCID: 0000-0001-9498-1214

OpenAlex ID: A5082172915

Small‐Molecule Stabilization of Protein–Protein Interactions: An Underestimated Concept in Drug Discovery?

2012 · Philipp Thiel, Markus Kaiser, et al. · Angewandte Chemie International Edition · 207

Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

2010 · Manuela Molzan, Benjamin Schumacher, et al. · Molecular and Cellular Biology · 128

A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface

2013 · Carolin Anders, Yusuke Higuchi, et al. · Chemistry & Biology · 106

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Structure of the p53 C‐terminus bound to 14‐3‐3: Implications for stabilization of the p53 tetramer

2010 · Benjamin Schumacher, Justine Mondry, et al. · FEBS Letters · 89

Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions

2020 · Eline Sijbesma, Emira Visser, et al. · Nature Communications · 72

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Stabilization of Protein–Protein Interactions in chemical biology and drug discovery

2015 · David Bier, Philipp Thiel, et al. · Progress in Biophysics and Molecular Biology · 53

Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein–protein interactions

2013 · Philipp Thiel, Lars Röglin, et al. · Chemical Communications · 47

EpiToolKit—a web server for computational immunomics

2008 · Magdalena Feldhahn, Philipp Thiel, et al. · Nucleic Acids Research · 25

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DNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats

2015 · Orlando de Lange, Christina Wolf, et al. · Nucleic Acids Research · 24

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Niedermolekulare Stabilisatoren von Protein‐Protein‐Wechselwirkungen: ein unterschätztes Konzept in der Wirkstoffentwicklung?

2012 · Philipp Thiel, Markus Kaiser, et al. · Angewandte Chemie · 23

FRED—a framework for T-cell epitope detection

2009 · Magdalena Feldhahn, Pierre Dönnes, et al. · Bioinformatics · 22

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Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins

2012 · Lars Röglin, Philipp Thiel, et al. · Proceedings of the National Academy of Sciences · 19

Blocked Inverted Indices for Exact Clustering of Large Chemical Spaces

2014 · Philipp Thiel, Lisa Sach-Peltason, et al. · Journal of Chemical Information and Modeling · 13

InVADo: Interactive Visual Analysis of Molecular Docking Data

2023 · Marco Schäfer, Nicolas Brich, et al. · IEEE Transactions on Visualization and Computer Graphics · 12

Portals and Web-Based Resources for Virtual Screening

2016 · Jens Krüger, Philipp Thiel, et al. · Current Drug Targets · 11

ballaxy: web services for structural bioinformatics

2014 · Anna Katharina Hildebrandt, Daniel Stöckel, et al. · Bioinformatics · 11

ChemInform Abstract: Small‐Molecule Stabilization of Protein—Protein Interactions: An Underestimated Concept in Drug Discovery?

2012 · Philipp Thiel, Markus Kaiser, et al. · ChemInform · 2

Binary complex of 14-3-3σ/p53 pT387-peptide and implications for stabilization

2010 · Benjamin Schumacher, Justine Mondry, et al. · Acta Crystallographica Section A Foundations of Crystallography · 1

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Computational Methods for the Modulation of Protein-Protein Interactions

2015 · Thiel, Philipp · Universitätsbibliothek Tübingen

DNA-binding proteins from marine bacteria expand the sequence diversity of known TALE-like repeats

2015 · Orlando de Lange, Christina Wolf, et al. · Nucleic Acids Research

Deterministic clustering of the available chemical space

2013 · Philipp Thiel, Lisa Peltason, et al. · Journal of Cheminformatics

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Deterministic clustering of the available chemical space

2013 · Oliver Kohlbacher, Philipp Thiel, et al.

CCDC 853443: Experimental Crystal Structure Determination

2013 · Anders, C., Higuchi, Y., et al. · The Cambridge Structural Database

Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening

2011 · P. Thiel, C. Ottmann · Worldwide Protein Data Bank

Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilisator Fusicoccin A

2010 · C. Anders, Y. Higuchi, et al. · Worldwide Protein Data Bank

Works count: 35

Citation count: 865

H-index: 13

I10-index: 16