Get started
Author

Yan Yi Chan

Observed names: Chan, Yan Yi, Yan Y. Chan, Yan-Yi Chan
ORCID: 0000-0002-0145-4878
Observed ORCID: 0000-0002-0145-4878
OpenAlex ID: A5082642152
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
2019 · Agnieszka Czechowicz, Rahul Palchaudhuri, et al. · Nature Communications · 207
PDF
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells
2015 · Jennifer L. Gori, Jason M. Butler, et al. · Journal of Clinical Investigation · 113
A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates
2017 · Stefan Radtke, Jennifer E. Adair, et al. · Science Translational Medicine · 110
Purification of Human CD34+CD90+ HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy
2020 · Stefan Radtke, Dnyanada Pande, et al. · Molecular Therapy — Methods & Clinical Development · 43
PDF
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures
2023 · Kyomi J. Igarashi, Iwo Kucinski, et al. · Blood Advances · 32
PDF
Irradiation- and busulfan-free stem cell transplantation in Fanconi anemia using an anti-CD117 antibody: a phase 1b trial
2025 · Rajni Agarwal, Alice Bertaina, et al. · Nature Medicine · 27
PDF
MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells
2018 · Stefan Radtke, Yan-Yi Chan, et al. · Experimental Hematology · 22
Non-genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia
2022 · Yan Yi Chan, Pui Yan Ho, et al. · Transplantation and Cellular Therapy · 12
Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia
2023 · Rajni Agarwal, Alice Bertaina, et al. · Blood · 9
Targeted hematopoietic stem cell depletion through SCF-blockade
2024 · Yan Yi Chan, Pui Yan Ho, et al. · Stem Cell Research & Therapy · 6
PDF
Hematopoiesis after anti-CD117 monoclonal antibody treatment in the settings of wild-type and Fanconi anemia mice
2024 · Morgane Denis, Leah Swartzrock, et al. · Haematologica · 4
PDF
Sort-purification of human CD34 + CD90 + cells reduces target cell population and improves lentiviral transduction for gene therapy
2019 · Stefan Radtke, Dnyanada Pande, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
PDF
Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia
2022 · Yan Yi Chan, Rofida Nofal, et al. · Transplantation and Cellular Therapy · 3
Hematopoietic stem cell transplantation using briquilimab (Anti-CD117 Antibody-Conditioning), immunosuppression and TCRαβ+ T-cell/CD19+ B-cell depleted haploidentical grafts in patients with fanconi anemia: An approach without irradiation, busulfan and calcineurin inhibitors.
2025 · Rajni Agarwal, Alice Bertaina, et al. · Blood · 1
PDF
Hematopoietic Recovery in Fanconi Anemia Patients Utilizing a Novel Anti-CD117 Antibody-Containing, Irradiation/Busulfan-Free Haploidentical Hematopoietic Stem Cell Transplant Regimen
2025 · Charmaine Soco, Mark Krampf, et al. · Transplantation and Cellular Therapy · 1
Identification and Characterization of a Distinct, Evolutionarily Conserved HSC Phenotype Associated with and Predicting Multi-Lineage Engraftment
2016 · Stefan Radtke, Morgan A. Giese, et al. · Blood · 1
Targeted Hematopoietic Stem Cell Conditioning through SCF-Blockade
2025 · Yan Yi Chan, Pui Yan Ho, et al. · Transplantation and Cellular Therapy
Evaluation of Bone Marrow in Fanconi Anemia Patients Treated with Briquilimab Antibody-Based Conditioning and TCRαβ+ T-Cell/CD19+ B-Cell Depleted Haploidentical Grafts
2024 · Charmaine Fay Soco, Mark R. Krampf, et al. · Blood
Initial Results from Stanford Children’s Fanconi Anemia Clinical Trial Using JSP191 Antibody Conditioning and TCRαβ+ T-Cell/CD19+ B-Cell Depleted Grafts
2023 · Rajni Agarwal, Alice Bertaina, et al. · Transplantation and Cellular Therapy
Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102
2022 · Rofida Nofal, Yan Yi Chan, et al. · Blood
Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation
2022 · Yan Yi Chan, Pui Yan Ho, et al. · Blood
Fully Closed, Large-Scale, and Clinical Grade Cell Sorting of Hematopoietic Stem Cell (HSC)-Enriched CD90+ Cells for Transplantation and Gene Therapy
2019 · Stefan Radtke, Margaret Cui, et al. · Blood
Conserved Lineage Development in Human and Nonhuman Primate Hematopoiesis
2016 · Stefan Radtke, Yan-Yi Chan, et al. · Blood
Works count: 26
Citation count: 595
H-index: 9
I10-index: 8
Year
Topic
Type