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Dingsheng Wen

Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties
2014 · Yanmei Zhang, Micky D. Tortorella, et al. · ACS Medicinal Chemistry Letters · 51
Polymorphisms of peroxisome proliferator-activated receptor γ (PPARγ) and cluster of differentiation 36 (CD36) associated with valproate-induced obesity in epileptic patients
2018 · Xupeng Bai, Chuncao Xu, et al. · Psychopharmacology · 38
Simultaneous determination of curcumin, tetrahydrocurcumin, quercetin, and paeoniflorin by UHPLC-MS/MS in rat plasma and its application to a pharmacokinetic study
2019 · Weilan Yu, Dingsheng Wen, et al. · Journal of Pharmaceutical and Biomedical Analysis · 34
Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high plasma exposure of rosuvastatin and its metabolites
2018 · Xue Bai, Bin Zhang, et al. · Acta Pharmacologica Sinica · 33
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Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates
2012 · Dingsheng Wen, Aiming Liu, et al. · Journal of Applied Toxicology · 33
Magnetic/Acoustic Dual‐Controlled Microrobot Overcoming Oto‐Biological Barrier for On‐Demand Multidrug Delivery against Hearing Loss
2024 · Xinyang Yi, Lifang Guo, et al. · Small · 24
Reversible opening of the blood-labyrinth barrier by low-pressure pulsed ultrasound and microbubbles for the treatment of inner ear diseases
2024 · Yuanwei He, Ziyu Chen, et al. · Journal of Controlled Release · 21
A rapid and simple HPLC–MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients
2017 · Dingsheng Wen, Ziyi Chen, et al. · Journal of Pharmaceutical and Biomedical Analysis · 16
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Association of Valproic Acid and Its Main Metabolites’ Plasma Concentrations with Clinical Outcomes among Epilepsy Patients: A 10-Year Retrospective Study Based on Therapeutic Drug Monitoring
2024 · Rui-tong Li, Zi-yi Chen, et al. · Drug Metabolism and Disposition · 13
Multifunctional nanocomposite-driven microneedles enabling bacteria capturing, detecting, and killing for precision treatment of acne with varying severities
2025 · Huaan Li, Hanqi Li, et al. · Chemical Engineering Journal · 8
A validated LC–MS/MS method for the simultaneous determination of thalidomide and its two metabolites in human plasma: Application to a pharmacokinetic assay
2018 · Fulin Jiang, Xiang Peng, et al. · Biomedical Chromatography · 5
A fast-slow liposome based “orthodox-unexpected interplay” strategy for bacterial otitis media and associated hearing loss
2025 · Huaan Li, Letian Cao, et al. · Journal of Controlled Release · 4
Pharmacomicrobiomics: Exploring the role of gut microbiota in type 2 diabetes and antidiabetic drug mechanisms
2025 · Dingsheng Wen, Xiangyue Wang, et al. · Nutrition Metabolism and Cardiovascular Diseases · 4
Glycyrrhizic acid and its carrier-free micellar formulation: Unraveling the potential for enhanced oral prevention of hearing loss
2025 · Huaan Li, Bohan Lin, et al. · International Journal of Pharmaceutics X · 4
Pharmacokinetics and Bioavailability Study of a Novel Smoothened Inhibitor TPB15 for Treatment of Triple-Negative Breast Cancer in Rats by High Performance Liquid Chromatography-Mass Spectrometry
2024 · Bo-yu Chen, Jia-huan Xu, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 3
Tracking the spatiotemporal journey of chitosan nanoparticles across ear physiological barriers: Mechanisms and pathways
2026 · Dingsheng Wen, Liping Zhang, et al. · Drug Metabolism and Disposition · 2
Predictive biomarkers for valproic acid-induced hepatotoxicity in Chinese patients with epilepsy: the role of metabolites and genetic polymorphisms
2025 · Dingsheng Wen, Zhuojia Chen, et al. · Food and Chemical Toxicology · 1
Plasma Protein Binding, Biostability, Metabolite Profiling, and CYP450 Phenotype of TPB15 Across Different Species: A Novel Smoothened Inhibitor for TNBC Therapy
2025 · Dingsheng Wen, Boyu Chen, et al. · Pharmaceutics · 1
A rapid and sensitive UHPLC–MS/MS method for quantification of 83b1 in plasma and its application to bioavailability study in rats
2016 · Dingsheng Wen, Jing Guo, et al. · Journal of Pharmaceutical and Biomedical Analysis · 1
TLN1 as a potential prognostic biomarker for cervical cancer patients undergoing cisplatin treatment
2026 · Xiangyue Wang, Shiyuan Feng, et al. · Discover Oncology
Shugan Paidu Decoction promotes cuproptosis of hepatoma cells by downregulating STAT3 levels
2026 · Sasa Chen, Jinxian Li, et al. · Journal of Holistic Integrative Pharmacy
Development and Validation of LC-MS/MS Method for A15 and its Application in Pharmacokinetic Studies
2022 · boyu Chen, Dingsheng Wen, et al. · SSRN Electronic Journal
Determination of a novel Aurora-A (AurA) kinase AKI603 by UPLC-MS/MS and its application to a bioavailability study in rat
2016 · Zhenzhen Zhao, Lingjie Huang, et al. · Journal of Pharmaceutical and Biomedical Analysis
Works count: 23
Citation count: 296
H-index: 9
I10-index: 9
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