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Alex J. Félix

Observed names: Alex J Félix, Alex J. Felix, Félix, Álex J.
ORCID: 0000-0002-7145-7169
Observed ORCID: 0000-0002-7145-7169
OpenAlex ID: A5083034116
Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching
2023 · Jennine M. Dawicki-McKenna, Alex J. Felix, et al. · Nature Communications · 40
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Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells
2016 · Gizem Bener, Alex J. Félix, et al. · BMC Immunology · 31
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Nucleic acids therapeutics using PolyPurine Reverse Hoogsteen hairpins
2020 · Véronique Noé, Eva Aubets, et al. · Biochemical Pharmacology · 24
Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer
2017 · Carlos J. Ciudad, Laura Rodríguez, et al. · Current Medicinal Chemistry · 24
Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells
2018 · Miriam Marlene Medina Enríquez, Alex J. Félix, et al. · PLoS ONE · 20
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Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells
2018 · Alex J. Félix, Carlos J. Ciudad, et al. · Biochemical Pharmacology · 16
Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)
2022 · Anna Aviñó, Carlos Cuestas-Ayllón, et al. · International Journal of Molecular Sciences · 14
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Correction of the aprt Gene Using Repair-Polypurine Reverse Hoogsteen Hairpins in Mammalian Cells
2019 · Alex J. Félix, Carlos J. Ciudad, et al. · Molecular Therapy — Nucleic Acids · 13
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Silencing PD-1 and PD-L1: The Potential of Polypurine Reverse Hoogsteen Hairpins for the Elimination of Tumor Cells
2019 · Carlos J Ciudad, Mariam Marlene Medina Enriquez, et al. · Immunotherapy · 11
Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
2020 · Eva Aubets, Alex J. Félix, et al. · International Journal of Molecular Sciences · 10
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Synthesis and validation of DOPY: A new gemini dioleylbispyridinium based amphiphile for nucleic acid transfection
2021 · Eva Aubets, Rosa Griera, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 9
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Gene Correction of Point Mutations Using PolyPurine Reverse Hoogsteen Hairpins Technology
2020 · Alex J. Félix, Anna Solé, et al. · Frontiers in Genome Editing · 7
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A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells
2019 · Valentina Maggio, Verónica Cánovas, et al. · Cancer Letters · 5
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Functional profiling of STXBP1 missense variants using a novel dual‐readout fluorometric assay
2026 · Elisa A. Waxman, Jennine M. Dawicki‐McKenna, et al. · Epilepsia
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Biallelic IRAK4 Variants Associated with Severe Neurological Autoinflammation: An Expansion of the Clinical Phenotype
2026 · Emma K. Wiener, Rocio Rius, et al. · medRxiv
Translatable electrophysiological and behavioral abnormalities in a humanized model of SYNGAP1-disorder
2026 · Alex J. Felix, Brandon L. Brown, et al. · Molecular Psychiatry
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Detection and validation of G-quadruplex motifs to silence Thymidylate synthase using Polypurine Reverse Hoogsteen Hairpins
2019 · E. Auberts, Alex J. Félix, et al. · DIGITAL.CSIC (Spanish National Research Council (CSIC))
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Gene silencing of Thymidylate Synthase in prostate cancer cells using Polypurine Reverse Hoogsteen Hairpins
2019 · Eva Aubets, Alex J. Félix, et al. · DIGITAL.CSIC (Spanish National Research Council (CSIC))
Thymidylate Synthase gene silencing by Polypurine Reverse Hoogsteen Hairpins in prostate cancer cells as cancer therapy
2019 · Eva Aubets, Alex J. Félix, et al. · DIGITAL.CSIC (Spanish National Research Council (CSIC))
Polypurine Reverse Hoogsteen Hairpins as a tool for gene repair and editing
2017 · Carlos Julián Ciudad i Gómez, Anna Solé Ferré, et al. · Research Signpost eBooks
Annotation: Hypertension inPopulations ofAfrican Origin
1997 · Sharon Conover, Alex J. Félix, et al.
Works count: 22
Citation count: 224
H-index: 10
I10-index: 10
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