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Arseniy Butrin

Observed names: A. Butrin, Butrin, Arseniy
Institution: Yale University
OpenAlex ID: A5083192463
A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid
2020 · Wei Zhu, Peter F. Doubleday, et al. · Journal of the American Chemical Society · 30
Development of Ligands and Degraders Targeting MAGE-A3
2024 · Ke Li, Mackenzie W. Krone, et al. · Journal of the American Chemical Society · 17
Rational Design, Synthesis, and Mechanism of (3 S ,4 R )-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase
2022 · Wei Zhu, Arseniy Butrin, et al. · Journal of the American Chemical Society · 17
Remarkable and Unexpected Mechanism for (S)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase
2021 · Wei Zhu, Peter F. Doubleday, et al. · Journal of the American Chemical Society · 17
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase
2021 · Sida Shen, Arseniy Butrin, et al. · Journal of the American Chemical Society · 12
The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil
2021 · Dariush C. Forouzesh, Brett A. Beaupre, et al. · Biochemistry · 10
Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase
2021 · Brett A. Beaupre, Dariush C. Forouzesh, et al. · Biochemistry · 9
Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase
2022 · Arseniy Butrin, Anastassiya Butrin, et al. · Journal of Biological Chemistry · 8
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Structural and Kinetic Analyses Reveal the Dual Inhibition Modes of Ornithine Aminotransferase by (1 S ,3 S )-3-Amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic Acid (BCF 3 )
2020 · Arseniy Butrin, Brett A. Beaupre, et al. · ACS Chemical Biology · 8
Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury
2024 · Davis H. Chase, Adrian M. Bebenek, et al. · Angewandte Chemie International Edition · 6
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The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mono‐ and Biruthenium Polypyridyl Complexes with G‐Quadruplex DNA
2017 · Clinton G. Mikek, Venkata R. Machha, et al. · European Journal of Inorganic Chemistry · 5
Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3S,4S)-3-Amino-4-fluorocyclopentenecarboxylic Acid
2023 · Sida Shen, Arseniy Butrin, et al. · Molecules · 2
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Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury
2024 · Davis H. Chase, Adrian M. Bebenek, et al. · Angewandte Chemie · 1
Correction to “Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase”
2023 · Wei Zhu, Arseniy Butrin, et al. · Journal of the American Chemical Society
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Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH Anaerobically
2021 · A. Butrin, B. Beaupre, et al. · Worldwide Protein Data Bank
Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine and NADPH Anaerobically
2021 · A. Butrin, B. Beaupre, et al. · Worldwide Protein Data Bank
Ornithine Aminotransferase (OAT) cocrystallized with its inactivator - (1S,3S)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid
2021 · A. Butrin, D. Catlin, et al. · Worldwide Protein Data Bank
Porcine Dihydropyrimidine Dehydrogenase (DPD) soaked with 5-Ethynyluracil (5EU), NADPH - 20 minutes
2021 · A. Butrin, D. Forouzesh, et al. · Worldwide Protein Data Bank
Porcine Dihydropyrimidine Dehydrogenase (DPD) crosslinked with 5-Ethynyluracil (5EU)
2021 · A. Butrin, D. Forouzesh, et al. · Worldwide Protein Data Bank
Porcine Dihydropyrimidine dehydrogenase (DPD) complexed with 5-Ethynyluracil (5EU) - Open Form
2021 · A. Butrin, D. Forouzesh, et al. · Worldwide Protein Data Bank
The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1S,3S)-3-amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid.
2020 · A. Butrin, B. Beaupre, et al. · Worldwide Protein Data Bank
Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators
2019 · W. Zhu, P.T. Doubleday, et al. · Worldwide Protein Data Bank
Works count: 23
Citation count: 142
H-index: 8
I10-index: 6
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