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Laura Hulea

Targeting the translation machinery in cancer
2015 · Mamatha Bhat, Nathaniel Robichaud, et al. · Nature Reviews Drug Discovery · 792
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
2015 · Masahiro Morita, Simon-Pierre Gravel, et al. · Cell Cycle · 549
mTOR as a central regulator of lifespan and aging
2019 · David Papadopoli, Karine Boulay, et al. · F1000Research · 441
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mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1
2017 · Masahiro Morita, Julien Prudent, et al. · Molecular Cell · 373
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
2019 · Shuo Liu, Simone Hausmann, et al. · Cell · 210
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nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
2016 · Valentina Gandin, Laia Masvidal, et al. · Genome Research · 204
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The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway
2016 · Mélissa Carbonneau, Laurence M. Gagné, et al. · Nature Communications · 180
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Serine Deprivation Enhances Antineoplastic Activity of Biguanides
2014 · Simon-Pierre Gravel, Laura Hulea, et al. · Cancer Research · 138
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
2018 · Laura Hulea, Simon-Pierre Gravel, et al. · Cell Metabolism · 91
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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
2021 · Bianca J. Lee, Jacob A. Boyer, et al. · Nature Chemical Biology · 82
CUX1 transcription factors: From biochemical activities and cell-based assays to mouse models and human diseases
2012 · Laura Hulea, Alain Nepveu · Gene · 77
Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis
2021 · Maxime Uriarte, Nadine Sen Nkwe, et al. · Nature Communications · 76
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mTOR-sensitive translation: Cleared fog reveals more trees
2017 · Laia Masvidal, Laura Hulea, et al. · RNA Biology · 73
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RAS Transformation Requires CUX1-Dependent Repair of Oxidative DNA Damage
2014 · Zubaidah M. Ramdzan, Charles Vadnais, et al. · PLoS Biology · 62
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A hydride transfer complex reprograms NAD metabolism and bypasses senescence
2021 · Sebastian Igelmann, Frédéric Lessard, et al. · Molecular Cell · 60
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin
2021 · David Papadopoli, Oro Uchenunu, et al. · Neoplasia · 54
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PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
2020 · Slim Mzoughi, Jia Yi Fong, et al. · Nature Communications · 51
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Autocrine Activation of the Wnt/β-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers
2014 · Charles Vadnais, Peiman Shooshtarizadeh, et al. · Biology Open · 44
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SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex
2015 · Yongmei Feng, Anthony B. Pinkerton, et al. · Cancer Research · 40
Biomedical Potential of mTOR Modulation by Nanoparticles
2016 · Laura Hulea, Zoran Markovic, et al. · Trends in biotechnology · 33
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax
2022 · Katie Fooks, Gabriela Galicia-Vazquez, et al. · Journal of Experimental & Clinical Cancer Research · 31
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ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis
2024 · Yassine El Bakkouri, Rony Chidiac, et al. · Nature Communications · 27
Dengue virus and Zika virus alter endoplasmic reticulum-mitochondria contact sites to regulate respiration and apoptosis
2024 · Wesley Freppel, Viviana Andrea Barragan Torres, et al. · iScience · 25
PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity
2024 · Mirian Krystel De Siqueira, Gaoyan Li, et al. · Cell Reports · 21
CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
2023 · Mathieu Neault, Charles-Étienne Lebert-Ghali, et al. · Cell Reports · 15
Works count: 69
Citation count: 3,807
H-index: 23
I10-index: 27
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