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Leon G. J. Frenken

Observed names: Frenken LGJ, L G Frenken, L G J Frenken, L. Frenken, L. G. Frenken, L. G. J. FRENKEN, L. G. J. Frenken, L.G.J. Frenken, LGJ Frenken, Leo Gerardus Joseph Frenken, Leon Frenken, Leon G J Frenken, Leon G.J Frenken, Leon G.J. Frenken, Leon GJ Frenken
Observed institutions: Centre National de la Recherche Scientifique, Unilever (United Kingdom), ETH Zurich, Unilever (Netherlands), Architecture et Fonction des Macromolécules Biologiques, Unilever Foods Innovation Centre, Nederlands Instituut Voor Zuivel Oonderzoek, Université Laval, Institute of Food, Nutrition, and Health, Unilever Research and Development Vlaardingen, Wageningen University & Research
ORCID: 0000-0001-5417-3706
Observed ORCID: 0000-0001-5417-3706
OpenAlex ID: A5083427189
Single‐domain antibody fragments with high conformational stability
2002 · Mireille Dumoulin, Katja Conrath, et al. · Protein Science · 661
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Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies
1999 · R.H.J. van der Linden, L.G.J. Frenken, et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 483
Isolation of antigen specific Llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae
2000 · Leon G.J Frenken, Richard H.J van der Linden, et al. · Journal of Biotechnology · 291
The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate
1993 · M.E.M. Noble, A. Cleasby, et al. · FEBS Letters · 283
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Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features
2000 · Michiel M. Harmsen, Robin C. Ruuls, et al. · Molecular Immunology · 223
Thermal Unfolding of a Llama Antibody Fragment: A Two-State Reversible Process
2000 · Janice M. J. Pérez, Jean G. Renisio, et al. · Biochemistry · 205
Camelid Heavy-Chain Variable Domains Provide Efficient Combining Sites to Haptens
2000 · Silvia Spinelli, Leon G. J. Frenken, et al. · Biochemistry · 163
Lactobacilli Expressing Variable Domain of Llama Heavy‐Chain Antibody Fragments (Lactobodies) Confer Protection against Rotavirus‐Induced Diarrhea
2006 · Neha Pant, Anna Hultberg, et al. · The Journal of Infectious Diseases · 158
Isolation of Llama Antibody Fragments for Prevention of Dandruff by Phage Display in Shampoo
2005 · Edward Dolk, Marcel van der Vaart, et al. · Applied and Environmental Microbiology · 131
Role of the lipB gene product in the folding of the secreted lipase of Pseudomonas glumae
1993 · Leon G. J. Frenken, Arjan de Groot, et al. · Molecular Microbiology · 95
Lateral recognition of a dye hapten by a llama VHH domain
2001 · Silvia Spinelli, Mariella Tegoni, et al. · Journal of Molecular Biology · 93
An accessory gene, lipB, required for the production of active Pseudomonas glumae lipase
1993 · Leon G.J. Frenken, J. Wil Bos, et al. · Molecular Microbiology · 92
Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection
2013 · Daisuke Tokuhara, Beatriz Álvarez, et al. · Journal of Clinical Investigation · 90
Cloning of the Pseudomonas glumae lipase gene and determination of the active site residues
1992 · L G Frenken, M R Egmond, et al. · Applied and Environmental Microbiology · 88
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Induced refolding of a temperature denatured llama heavy‐chain antibody fragment by its antigen
2005 · Edward Dolk, Cees van Vliet, et al. · Proteins Structure Function and Bioinformatics · 79
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The structure of the llama heavy chain constant genes reveals a mechanism for heavy-chain antibody formation
1999 · B. P. Woolven, Leon G. J. Frenken, et al. · Immunogenetics · 78
Llama Antibodies against a Lactococcal Protein Located at the Tip of the Phage Tail Prevent Phage Infection
2005 · Hans J. W. De Haard, Sandra Bezemer, et al. · Journal of Bacteriology · 76
Anti-Rotavirus Protein Reduces Stool Output in Infants With Diarrhea: A Randomized Placebo-Controlled Trial
2013 · Shafiqul A. Sarker, Martin Jäkel, et al. · Gastroenterology · 73
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Recent advances in the large-scale production of antibody fragments using lower eukaryotic microorganisms
1998 · L.G.J. Frenken, J.G.M. Hessing, et al. · Research in Immunology · 64
Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial
2018 · Cornelius M Smuts, Tonderayi M Matsungo, et al. · American Journal of Clinical Nutrition · 61
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Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challenges
2013 · Suzan Wopereis, Danielle Wolvers, et al. · BMC Medical Genomics · 59
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Preventing Phage Lysis of Lactococcus Lactis in Cheese Production Using A Neutralizing Heavy-Chain Antibody Fragment from Llama
2002 · A.M. Ledeboer, S. Bezemer, et al. · Journal of Dairy Science · 55
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Inhibition of Iron Absorption by Calcium Is Modest in an Iron-Fortified, Casein- and Whey-Based Drink in Indian Children and Is Easily Compensated for by Addition of Ascorbic Acid
2014 · Thomas Walczyk, Sumithra Muthayya, et al. · Journal of Nutrition · 54
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Improved production and function of llama heavy chain antibody fragments by molecular evolution
2000 · Richard H.J van der Linden, Bernard de Geus, et al. · Journal of Biotechnology · 51
Lactobacilli Producing Bispecific Llama-Derived Anti-Rotavirus Proteins in vivo for Rotavirus-Induced Diarrhea
2011 · Neha Pant, Harold Marcotte, et al. · Future Microbiology · 45
Works count: 51
Citation count: 4,151
H-index: 32
I10-index: 37
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