Author

Jose M. Orozco

Observed names: Jose Miguel Orozco, Jose Orozco Segrera, Jose M. Orozco

Institutions: Harvard University, Dana-Farber Cancer Institute

Observed institutions: Broad Institute, Northeastern University, National Institutes of Health, Howard Hughes Medical Institute, Harvard University, National Human Genome Research Institute, Dana-Farber Cancer Institute, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

ORCID: 0000-0002-4587-0777

Observed ORCID: 0000-0002-4587-0777

OpenAlex ID: A5083745931

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

2013 · Stephen C. J. Parker, Michael L. Stitzel, et al. · Proceedings of the National Academy of Sciences · 665

SAMTOR is an S -adenosylmethionine sensor for the mTORC1 pathway

2017 · Xin Gu, Jose M. Orozco, et al. · Science · 570

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

2014 · Lynne Chantranupong, Rachel L. Wolfson, et al. · Cell Reports · 466

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

2017 · Rachel L. Wolfson, Lynne Chantranupong, et al. · Nature · 332

Dihydroxyacetone phosphate signals glucose availability to mTORC1

2020 · Jose M. Orozco, Patrycja A. Krawczyk, et al. · Nature Metabolism · 247

The intrinsic substrate specificity of the human tyrosine kinome

2024 · Tomer M. Yaron-Barir, Brian A. Joughin, et al. · Nature · 152

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction

2021 · Kendall J. Condon, Jose M. Orozco, et al. · Proceedings of the National Academy of Sciences · 132

Filamin and Phospholipase C-ε Are Required for Calcium Signaling in the Caenorhabditis elegans Spermatheca

2013 · Ismar Kovacevic, Jose M. Orozco, et al. · PLoS Genetics · 55

The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator

2016 · Clint D.J. Tavares, Kfir Sharabi, et al. · Journal of Biological Chemistry · 38

Signal transduction in human cells by metabolites derived from methionine and glucose

2021 · Jose M. Orozco · DSpace@MIT (Massachusetts Institute of Technology)

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

2017 · Kuang Shen, Sabrina Petri, et al. · DSpace@MIT (Massachusetts Institute of Technology)

Works count: 11

Citation count: 2,657

H-index: 9

I10-index: 9