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Marie-Aude Guié

Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus
2013 · Alex Lipovsky, Andreea Popa, et al. · Proceedings of the National Academy of Sciences · 185
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding
2020 · Kevin McCloskey, Eric A. Sigel, et al. · Journal of Medicinal Chemistry · 171
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Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
2020 · Niklas Mejhert, Leena Kuruvilla, et al. · Molecular Cell · 123
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Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library
2015 · Alexander Litovchick, Christoph E. Dumelin, et al. · Scientific Reports · 100
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Discovery of Nanomolar DCAF1 Small Molecule Ligands
2023 · Alice Shi Ming Li, Serah Kimani, et al. · Journal of Medicinal Chemistry · 66
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Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology
2016 · Holly H. Soutter, Matthew A. Clark, et al. · Proceedings of the National Academy of Sciences · 60
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Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target
2018 · Dean G. Brown, Giles A. Brown, et al. · SLAS DISCOVERY · 52
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry
2021 · John P. Guilinger, Archna Archna, et al. · Bioorganic & Medicinal Chemistry · 50
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Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
2019 · Alexander Litovchick, Xia Tian, et al. · Molecules · 37
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Synthesis and Preliminary In Vitro Evaluation of Antimycobacterial Activity of New Pyrrolo[1,2- a ]quinoxaline-carboxylic Acid Hydrazide Derivatives
2004 · Jean Guillon, Robert C. Reynolds, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 34
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Protein–ligand data at scale to support machine learning
2025 · Aled M. Edwards, Dafydd R. Owen, et al. · Nature Reviews Chemistry · 27
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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins
2024 · Suzanne Ackloo, Fengling Li, et al. · Journal of Medicinal Chemistry · 27
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Programs to Facilitate Tuberculosis Drug Discovery: The Tuberculosis Antimicrobial Acquisition and Coordinating Facility
2007 · R. C. Goldman, B.E. Laughon, et al. · Infectious Disorders - Drug Targets · 26
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning
2023 · Shabbir Ahmad, Jin Xu, et al. · Journal of Medicinal Chemistry · 25
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Identification and Evaluation of Reversible Covalent Binders to Cys55 of Bfl-1 from a DNA-Encoded Chemical Library Screen
2024 · Simon C. C. Lucas, J. Henry Blackwell, et al. · ACS Medicinal Chemistry Letters · 22
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Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
2024 · Ashley L. Ramos, Eric R. Goedken, et al. · Journal of Medicinal Chemistry · 19
Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening
2024 · Inna V. Krieger, Subbarao Yalamanchili, et al. · ACS Infectious Diseases · 17
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
2024 · Koen F. W. Hekking, Sergio Maroto, et al. · Journal of Medicinal Chemistry · 12
Discovery of Small-Molecule Ligands for the E3 Ligase STUB1/CHIP from a DNA-Encoded Library Screen
2025 · Simon C. C. Lucas, Alexander G. Milbradt, et al. · ACS Medicinal Chemistry Letters · 9
Targeting the Moesin‐CD44 pathway for therapeutic intervention in Alzheimer’s disease
2020 · Vittorio Katis, William Bradshaw, et al. · Alzheimer s & Dementia · 2
A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response
2026 · Fiona Shilliday, Miguel Gancedo-Rodrigo, et al. · Nature Communications · 1
DNA-encoded chemical library-based identification of novel inhibitors targeting the essential LpxH enzyme in Gram-negative bacteria
2026 · Christodoulos Mitrogiannis, Johan Wannberg, et al. · ChemRxiv
DNA-encoded chemical library-based identification of novel inhibitors targeting the essential LpxH enzyme in Gram-negative bacteria
2026 · Christodoulos Mitrogiannis, Johan Wannberg, et al. · ChemRxiv
Abstract 6423: DNA-encoded chemical library screening for glue discovery for oncology targets
2026 · Anthony D. Keefe, Zhen Chen, et al. · Cancer Research
Abstract 6416: DEL-chemomics approach for the discovery of targeted protein degraders for cancer therapy
2026 · Ying Zhang, Anthony D. Keefe, et al. · Cancer Research
Works count: 29
Citation count: 1,065
H-index: 17
I10-index: 18
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