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Vanessa Zann
Observed name:
V. Zann
Institution:
Quotient Sciences Limited (United Kingdom)
Observed institutions:
AstraZeneca (United Kingdom),
Quotient Clinical (United Kingdom),
Quotient Sciences Limited (United Kingdom)
ORCID:
0000-0003-0747-181X
Observed ORCID:
0000-0003-0747-181X
OpenAlex ID:
A5083976305
On the Colonic Bacterial Metabolism of Azo-Bonded Prodrugsof 5-Aminosalicylic Acid
2014
·
Tiago Sousa
, Vipul Yadav
, et al.
·
Journal of Pharmaceutical Sciences
·
149
Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis
2015
·
Paloma Benito-Gallo
, Alessandro Franceschetto
, et al.
·
European Journal of Pharmaceutics and Biopharmaceutics
·
92
PDF
Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double‐Blind, Randomized, Placebo‐Controlled Phase 1 Clinical Study
2017
·
Hazel Hunt
, Kirsteen Donaldson
, et al.
·
Clinical Pharmacology in Drug Development
·
68
PDF
Safety, Pharmacokinetics, and Pharmacodynamics of ME-401, an Oral, Potent, and Selective Inhibitor of Phosphatidylinositol 3-Kinase P110δ, Following Single Ascending Dose Administration to Healthy Volunteers
2018
·
Ofir Moreno
, Todd Butler
, et al.
·
Clinical Therapeutics
·
28
PDF
Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect
2017
·
Tamás Solymosi
, Zsolt Ötvös
, et al.
·
Cancer Chemotherapy and Pharmacology
·
26
Linking in Vitro Lipolysis and Microsomal Metabolism for the Quantitative Prediction of Oral Bioavailability of BCS II Drugs Administered in Lipidic Formulations
2016
·
Paloma Benito-Gallo
, Maria Marlow
, et al.
·
Molecular Pharmaceutics
·
17
Palatability and physical properties of potassium-binding resin RDX7675: comparison with sodium polystyrene sulfonate
2017
·
Vanessa Zann
, John McDermott
, et al.
·
Drug Design Development and Therapy
·
15
PDF
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology
2022
·
Debra Tompson
, Mark Whitaker
, et al.
·
Pharmaceutical Research
·
13
PDF
Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772
2021
·
Debra J. Tompson
, Mark Whitaker
, et al.
·
Pharmaceutical Research
·
13
PDF
Digoxin net secretory transport in bronchial epithelial cell layers is not exclusively mediated by P-glycoprotein/MDR1
2013
·
Victoria Hutter
, David Y.S. Chau
, et al.
·
European Journal of Pharmaceutics and Biopharmaceutics
·
13
PDF
Evaluation of layers of the rat airway epithelial cell line RL-65 for permeability screening of inhaled drug candidates
2012
·
V. Hutter
, C. Hilgendorf
, et al.
·
European Journal of Pharmaceutical Sciences
·
4
PDF
Discovery and Model‐Informed Drug Development of a Controlled‐Release Formulation of Nonracemic Amisulpride that Reduces Plasma Exposure but Achieves Pharmacodynamic Bioequivalence in the Brain
2024
·
Seth C. Hopkins
, Siriporn Toongsuwan
, et al.
·
Clinical Pharmacology & Therapeutics
·
3
An Evaluation of the Pharmacodynamics, Safety, and Tolerability of the Potassium Binder RDX7675
2018
·
Bertram Pitt
, Vanessa Zann
, et al.
·
The Journal of Clinical Pharmacology
·
2
PDF
Smart Lipid-Based Drug Delivery Systems
2016
·
Paloma Benito-Gallo
, Pavel Gershkovich
, et al.
·
IMPERIAL COLLEGE PRESS eBooks
·
2
Formulation development and a Phase 1 clinical study of PF614-MPAR, an oxycodone prodrug with oral opioid overdose protection
2026
·
D. Lynn Kirkpatrick
, Linda A. Pestano
, et al.
·
Journal of Opioid Management
·
1
PDF
Co-administering clofazimine with infant formula enhances its oral bioavailability in rats and pigs
2025
·
Thomas Eason
, Ellie Ponsonby-Thomas
, et al.
·
European Journal of Pharmaceutics and Biopharmaceutics
·
1
A randomized, placebo‐controlled first‐in‐human study of oral TQS‐168 in healthy volunteers: Assessment of safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect
2024
·
Jonas Hannestad
, Steven Smith
, et al.
·
Clinical and Translational Science
·
1
PDF
Oral Site‐Directed Drug Delivery and Influence on PK
2021
·
Peter Scholes
, Vanessa Zann
, et al.
·
Wiley eBooks
·
1
Abstract CT157: Clinical pharmacokinetics and pharmacodynamics of ME-401, an oral, potent and selective inhibitor of phosphatidylinositol 3-kinase P110δ, following single ascending dose administration to healthy volunteers
2016
·
Ofir Moreno
, Robert Imani
, et al.
·
Cancer Research
·
1
Unexpected Effect of Digestion Products of Infant Formula in Enhancing the Solubilisation of Tolfenamic Acid During Digestion
2026
·
Thomas Eason
, Malinda Salim
, et al.
·
Pharmaceutics
PDF
Appendix: Formulation development and a Phase 1 clinical study of PF614-MPAR, an oxycodone prodrug with oral opioid overdose protection
2026
·
D. Lynn Kirkpatrick
, Linda A. Pestano
, et al.
·
Journal of Opioid Management
PDF
Permeability
2021
·
Chris Roe
, Vanessa Zann
·
Wiley eBooks
Novel formulation of abiraterone acetate with significantly higher bioavailability and eliminated food effect might allow higher abiraterone exposure and better patient outcome.
2018
·
Hristos Glavinas
, Tamás Solymosi
, et al.
·
Journal of Clinical Oncology
Abstract 14911: RDX227675, the Calcium Salt of a Novel Polystyrene Sulfonate-Based Resin, Reduces Potassium Absorption in Healthy Volunteers
2016
·
Vanessa Zann
, Chris Roe
, et al.
·
Circulation
14C Microtracer Approaches to Inform Formulation Development Strategies in Early Clinical Drug Development
2016
·
Vanessa Zann
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Works count:
29
Citation count:
450
H-index:
10
I10-index:
10
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