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João Pedro Pisco
Observed names:
J.P. Pisco,
Joao P. Pisco,
João P. Pisco,
João Pisco
Institutions:
LifeArc,
The Francis Crick Institute
Observed institutions:
LifeArc,
University of Dundee,
The Francis Crick Institute,
Wellcome Centre for Anti-Infectives Research,
National Institute for Medical Research
ORCID:
0000-0001-6763-7354
Observed ORCID:
0000-0001-6763-7354
OpenAlex ID:
A5084055567
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
2019
·
Beatriz Baragaña
, Barbara Forte
, et al.
·
Proceedings of the National Academy of Sciences
·
149
PDF
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
2021
·
Robert L. Summers
, Charisse Flerida A. Pasaje
, et al.
·
Cell chemical biology
·
75
PDF
Mechanism of Feedback Allosteric Inhibition of ATP Phosphoribosyltransferase
2012
·
Sònia Pedreño
, João Pedro Pisco
, et al.
·
Biochemistry
·
36
Uncoupling conformational states from activity in an allosteric enzyme
2017
·
João P. Pisco
, Cesira de Chiara
, et al.
·
Nature Communications
·
27
PDF
Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase
2017
·
Kamila J. Pacholarz
, Rebecca J. Burnley
, et al.
·
Structure
·
25
PDF
Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors
2023
·
Andrew J. Wilkinson
, Nicola Ooi
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
9
Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis
2026
·
Debbie M. Hunt
, João Pedro Pisco
, et al.
·
Nature Communications
·
2
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV-2 NSP14
2025
·
Elliott B. Smyth
, João P. Pisco
, et al.
·
ACS Medicinal Chemistry Letters
·
2
PDF
ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric activator 3-(2-Thienyl)-L-alanine
2016
·
C. de Chiara
, J.P. Pisco
, et al.
·
Worldwide Protein Data Bank
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Works count:
9
Citation count:
325
H-index:
6
I10-index:
5
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