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Mamoru Nukatsuka

Observed names: M Nukatsuka, M. NUKATSUKA, M. Nukatsuka, M., Nukatsuka, MAMORU NUKATSUKA, Mamoru NUKATSUKA, Nukatsuka Mamoru
Observed institutions: Otsuka (Japan), Hokkaido University, Taiho Pharmaceutical (Japan), Taiho Oncology (United States), Tokushima Bunri University, Tokushima University, The University of Osaka
ORCID: 0000-0001-9774-2526
Observed ORCID: 0000-0001-9774-2526
OpenAlex ID: A5084347479
Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats
1990 · H. Sakurai, K. Tsuchiya, et al. · Journal of Endocrinology · 165
Insulin-mimetic action of vanadyl complexes.
1990 · Hiromu SAKURAI, Koichiro TSUCHIYA, et al. · Journal of Clinical Biochemistry and Nutrition · 119
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Enhancement by streptozotocin of O−2 radical generation by the xanthine oxidase system of pancreatic β‐cells
1988 · Mamoru Nukatsuka, Hiromu Sakurai, et al. · FEBS Letters · 80
Importance of the concentration of ATP in rat pancreatic β cells in the mechanism of streptozotocin-induced cytotoxicity
1990 · M. Nukatsuka, Y. Yoshimura, et al. · Journal of Endocrinology · 76
Evidence that C4b-binding protein is an acute phase protein
1989 · Toshihiko Saeki, Sakae Hirose, et al. · Biochemical and Biophysical Research Communications · 58
Dendritic cells might be one of key factors for eliciting antitumor effect by chemoimmunotherapy in vivo
2004 · Hiroyuki Mushiake, Takuya Tsunoda, et al. · Cancer Immunology Immunotherapy · 44
Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks
2011 · NORIHIKO SUZUKI, FUMIO NAKAGAWA, et al. · Experimental and Therapeutic Medicine · 40
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Structure-Based Design of Specific Cathepsin Inhibitors and Their Application to Protection of Bone Metastases of Cancer Cells
2002 · N. Katunuma, H. Tsuge, et al. · Archives of Biochemistry and Biophysics · 38
Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, with irinotecan hydrochloride on human colorectal and gastric cancer xenografts.
2015 · Mamoru Nukatsuka, Fumio Nakagawa, et al. · PubMed · 37
Generation of alloxan free radicals in chemical and biological systems: Implication in the diabetogenic action of alloxan
1989 · Mamoru Nukatsuka, Hiromu Sakurai, et al. · Biochemical and Biophysical Research Communications · 32
Efficacy of Combination Chemotherapy Using a Novel Oral Chemotherapeutic Agent, TAS-102, with Oxaliplatin on Human Colorectal and Gastric Cancer Xenografts.
2015 · Mamoru Nukatsuka, Fumio Nakagawa, et al. · PubMed · 31
Antimetastatic and anticancer activity of S-1, a new oral dihydropyrimidine-dehydrogenase-inhibiting fluoropyrimidine, alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model
2004 · Mamoru Nukatsuka, Akio Fujioka, et al. · International Journal of Oncology · 31
Allopurinol protects pancreatic .BETA. cells from the cytotoxic effect of streptozotocin: In vitro study.
1990 · Mamoru NUKATSUKA, Yoshiyuki YOSHIMURA, et al. · Journal of Pharmacobio-Dynamics · 30
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Postsurgical oral administration of uracil and tegafur inhibits progression of micrometastasis of human breast cancer cells in nude mice.
1997 · J Kurebayashi, M Nukatsuka, et al. · PubMed · 28
Additive antitumor effect of concurrent treatment of 4-hydroxy tamoxifen with 5-fluorouracil but not with doxorubicin in estrogen receptor-positive breast cancer cells
2006 · Junichi Kurebayashi, Mamoru Nukatsuka, et al. · Cancer Chemotherapy and Pharmacology · 27
Combination therapy using oral S-1 and targeted agents against human tumor xenografts in nude mice
2012 · MAMORU NUKATSUKA, HITOSHI SAITO, et al. · Experimental and Therapeutic Medicine · 22
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Oral fluoropyrimidine may augment the efficacy of aromatase inhibitor via the down-regulation of estrogen receptor in estrogen-responsive breast cancer xenografts
2010 · Mamoru Nukatsuka, Hitoshi Saito, et al. · Breast Cancer Research and Treatment · 20
Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis
2002 · N. Katunuma, H. Tsuge, et al. · Advances in Enzyme Regulation · 16
Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis
2015 · YUJI SHIMAMOTO, MAMORU NUKATSUKA, et al. · International Journal of Molecular Medicine · 14
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Characterization of the Interaction between Human Protein S and C4b-Binding Protein (C4bp)1
1987 · Mamoru NUKATSUKA, Shigeharu NAGASAWA · The Journal of Biochemistry · 14
Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil
2017 · Kaoru Ishida, Chie Ito, et al. · Scientific Reports · 13
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Preclinical rationale for combined use of endocrine therapy and 5-fluorouracil but neither doxorubicin nor paclitaxel in the treatment of endocrine-responsive breast cancer
2009 · Junichi Kurebayashi, Mamoru Nukatsuka, et al. · Cancer Chemotherapy and Pharmacology · 13
Improved chemoradiation treatment using trifluridine in human colorectal cancer cells in vitro
2017 · Kazuaki Matsuoka, Takashi Kobunai, et al. · Biochemical and Biophysical Research Communications · 12
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Synthesis and Biological Evaluation of 7-Hydroxy-3,4-diphenyl-1,2-dihydroisoquinolines as New 4-Hydroxytamoxifen Analogues.
1997 · Masaru KIHARA, Motoki IKEUCHI, et al. · Chemical and Pharmaceutical Bulletin · 12
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Evaluation of a Novel Combination Therapy, Based on Trifluridine/Tipiracil and Fruquintinib, against Colorectal Cancer
2023 · Mamoru Nukatsuka, Akio Fujioka, et al. · Chemotherapy · 11
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Works count: 61
Citation count: 1,072
H-index: 17
I10-index: 26
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