Author

Timothy S. Luongo

Observed names: T.S. Luongo, TImothy S Luongo, Timothy Luongo, Timothy S Luongo, Timothy S. Luongo

Observed institutions: Northwestern University, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases, Institute of Molecular Biology and Biophysics, Vaccine Research Center, University of Pennsylvania, Temple University

ORCID: 0000-0001-7621-7992

Observed ORCID: 0000-0001-7621-7992

OpenAlex ID: A5084496844

Embryonic Stem Cell–Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

2015 · Mohsin Khan, Emily Nickoloff, et al. · Circulation Research · 753

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

2017 · Timothy S. Luongo, Jonathan P. Lambert, et al. · Nature · 394

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

2015 · Timothy S. Luongo, Jonathan P. Lambert, et al. · Cell Reports · 384

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

2013 · Tongqing Zhou, Jiang Zhu, et al. · Immunity · 366

Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease

2019 · Pooja Jadiya, Devin W. Kolmetzky, et al. · Nature Communications · 321

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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

2015 · Tongqing Zhou, Rebecca M. Lynch, et al. · Cell · 310

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SLC25A51 is a mammalian mitochondrial NAD+ transporter

2020 · Timothy S. Luongo, Jared M. Eller, et al. · Nature · 305

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics

2016 · Dhanendra Tomar, Zhiwei Dong, et al. · Cell Reports · 210

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The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis

2019 · N. Jaiswal, M.G. Gavin, et al. · Molecular Metabolism · 167

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Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

2019 · Alyssa A. Lombardi, Andrew A. Gibb, et al. · Nature Communications · 160

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MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress

2019 · Jonathan P. Lambert, Timothy S. Luongo, et al. · Circulation · 146

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

2014 · Priyamvada Acharya, William D. Tolbert, et al. · Journal of Virology · 115

Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function

2021 · Pieterjan Dierickx, Kun Zhu, et al. · Nature Cardiovascular Research · 71

The debate continues – What is the role of MCU and mitochondrial calcium uptake in the heart?

2020 · Joanne F. Garbincius, Timothy S. Luongo, et al. · Journal of Molecular and Cellular Cardiology · 44

Enhanced NCLX-dependent mitochondrial Ca2+ efflux attenuates pathological remodeling in heart failure

2022 · Joanne F. Garbincius, Timothy S. Luongo, et al. · Journal of Molecular and Cellular Cardiology · 34

Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

2013 · Priyamvada Acharya, Timothy S. Luongo, et al. · Structure · 32

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Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry

2011 · Priyamvada Acharya, Cajetan Dogo-Isonagie, et al. · ACS Chemical Biology · 32

mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia

2019 · Lauren M. Paolella, Sarmistha Mukherjee, et al. · Molecular Metabolism · 30

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Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

2013 · Priyamvada Acharya, Timothy S. Luongo, et al. · Journal of Virology · 27

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Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics

2024 · Khanh V. Doan, Timothy S. Luongo, et al. · Nature Cardiovascular Research · 22

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Skeletal Muscle-specific G Protein-coupled Receptor Kinase 2 Ablation Alters Isolated Skeletal Muscle Mechanics and Enhances Clenbuterol-stimulated Hypertrophy

2016 · Benjamin P. Woodall, Meryl C. Woodall, et al. · Journal of Biological Chemistry · 13

MCU gain-and loss-of-function models define the duality of mitochondrial calcium uptake in heart failure

2023 · Joanne F. Garbincius, Timothy S. Luongo, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5

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Abstract 16592: Excessive MCU-Mediated Mitochondrial Calcium Uptake During Chronic Stress Impairs Cardiac Contractility

2020 · Joanne F Garbincius, Timothy S Luongo, et al. · Circulation · 1

Genetic Rescue of Mitochondrial Calcium Efflux in Alzheimer's Disease Preserves Mitochondrial Function and Protects against Neuronal Cell Death

2017 · Pooja Jadiya, Alyssa A. Lombardi, et al. · Biophysical Journal · 1

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MCUb ( CCDC109B ) Modulates Mitochondrial Calcium Uptake Dynamics and Susceptibility to Calcium Overload and Permeability Transition

2016 · Jonathan Lambert, Timothy Luongo, et al. · The FASEB Journal · 1

Works count: 53

Citation count: 3,945

H-index: 20

I10-index: 21