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Akitomo Yokokawa

Observed names: Akitimo Yokokawa, Akitomo YOKOKAWA
ORCID: 0000-0002-6039-2953
Observed ORCID: 0000-0002-6039-2953
OpenAlex ID: A5084716503
EVIDENCE FOR THE VALIDITY OF CORTISOL 6β-HYDROXYLATION CLEARANCE AS A NEW INDEX FOR IN VIVO CYTOCHROME P450 3A PHENOTYPING IN HUMANS
2003 · Takashi Furuta, Atsushi Suzuki, et al. · Drug Metabolism and Disposition · 59
Plasma Profiling of Intact Isoflavone Metabolites by High-Performance Liquid Chromatography and Mass Spectrometric Identification of Flavone Glycosides Daidzin and Genistin in Human Plasma after Administration of Kinako
2008 · Kaori Hosoda, Takashi Furuta, et al. · Drug Metabolism and Disposition · 56
Identification and quantification of daidzein-7-glucuronide-4′-sulfate, genistein-7-glucuronide-4′-sulfate and genistein-4′,7-diglucuronide as major metabolites in human plasma after administration of kinako
2010 · Kaori Hosoda, Takashi Furuta, et al. · Analytical and Bioanalytical Chemistry · 53
Simultaneous determination of 6β-hydroxycortisol and cortisol in human urine by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity determined by the cortisol 6β-hydroxylation clearance
2003 · Takashi Furuta, Chieko Mori, et al. · Journal of Chromatography B · 25
Synthesis of multi-labeled cortisols and cortisones with 2H and 13C for study of cortisol metabolism in humans
2000 · Takashi Furuta, Nao Eguchi, et al. · Steroids · 24
Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
2012 · Hiromi Shibasaki, Kaori Hosoda, et al. · Drug Metabolism and Disposition · 21
Simultaneous determination of androstenedione, 11β-hydroxyandrostenedione, and testosterone in human plasma by stable isotope dilution mass spectrometry
2009 · Akitomo Yokokawa, Kazuhiro Yamamoto, et al. · Journal of Chromatography B · 16
Development and Validation of an LC–MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin
2022 · Seiya Ohki, Miyu Kunimatsu, et al. · Chemical and Pharmaceutical Bulletin · 11
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Identification of equol‐7‐glucuronide‐4′‐sulfate, monoglucuronides and monosulfates in human plasma of 2 equol producers after administration of kinako by LC ‐ ESI ‐ MS
2019 · Aki Obara, Mizuki Kinoshita, et al. · Pharmacology Research & Perspectives · 11
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Measurement of cortisol secretion rate by stable isotope methodology following oral administration of -labeled cortisol to a human subject
2002 · Yasuji Kasuya, Akitomo Yokokawa, et al. · Steroids · 11
Use of endogenous cortisol 6β-hydroxylation clearance for phenotyping in vivo CYP3A activity in women after sequential administration of an oral contraceptive (OC) containing ethinylestradiol and levonorgestrel as weak CYP3A inhibitors
2014 · Hiromi Shibasaki, Miyuki Kuroiwa, et al. · Steroids · 10
Use of 11α-deuterium labeled cortisol as a tracer for assessing reduced 11β-HSD2 activity in vivo following glycyrrhetinic acid ingestion in a human subject
2005 · Yasuji Kasuya, Akitomo Yokokawa, et al. · Steroids · 10
Sensitive and simultaneous quantitation of 6β‐hydroxycortisol and cortisol in human plasma by LC‐MS/MS coupled with stable isotope dilution method
2018 · Ryohei Hirano, Akitomo Yokokawa, et al. · Journal of Mass Spectrometry · 9
Separation and quantitative determination of 6α-hydroxycortisol and 6β-hydroxycortisol in human urine by high-performance liquid chromatography with ultraviolet absorption detection
2012 · Hiromi Shibasaki, Sawako Okamoto, et al. · Analytical and Bioanalytical Chemistry · 9
Evaluation of 11β-HSD activities in vivo following oral administration of cortisol-13C4,2H1 to a human subject
2003 · Yasuji Kasuya, Akitomo Yokokawa, et al. · Steroids · 9
The effect of water loading on the urinary ratio of cortisone to cortisol in healthy subjects and a new approach to the evaluation of the ratio as an index for in vivo human 11β-hydroxysteroid dehydrogenase 2 activity
2012 · Akitomo Yokokawa, Toru Takasaka, et al. · Steroids · 8
Plasma 6β‐hydroxycortisol to cortisol ratio as a less invasive cytochrome P450 3A phenotyping method
2023 · Ryohei Hirano, Akitomo Yokokawa, et al. · British Journal of Clinical Pharmacology · 7
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Dried blood spots analysis of 6β‐hydroxycortisol and cortisol using liquid chromatography/tandem mass spectrometry for calculating 6β‐hydroxycortisol to cortisol ratio
2021 · Ryohei Hirano, Akitomo Yokokawa, et al. · Journal of Mass Spectrometry · 7
URINARY 6β-HYDROXYCORTISOL/CORTISOL RATIO DOES NOT REFLECT IN VIVO CYP3A ACTIVITY IN HUMANS
2001 · Takashi FURUTA, Atsushi SUZUKI, et al. · Drug Metabolism and Pharmacokinetics · 6
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Midazolam Intoxication in a Premature Neonate
2020 · Mio Endo, Ryohei Hirano, et al. · Clinical Therapeutics · 5
Effect of UGT1A1, CYP3A and CES Activities on the Pharmacokinetics of Irinotecan and its Metabolites in Patients with UGT1A1 Gene Polymorphisms
2021 · Akitomo Yokokawa, Shun Kaneko, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 4
Quantification of Melatonin, Caffeine, and Paraxanthine in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry
2024 · Akitomo Yokokawa, Hiroki Takano, et al. · Chromatographia · 3
Validation of the plasma half-life of 11α-deuterium cortisol as a sensitive index for the analysis of human 11β-HSD2 activity in vivo
2005 · Yasuji Kasuya, Akitimo Yokokawa, et al. · Steroids · 1
Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity
2026 · Akitomo Yokokawa, Hayato Shimazaki, et al. · British Journal of Clinical Pharmacology
Quantification of fluticasone propionate in human plasma by LC–MS/MS and its application in the pharmacokinetic study of nasal spray at clinical doses
2023 · Aya Yamagata, Rena Adachi, et al. · Drug Metabolism and Pharmacokinetics
Works count: 30
Citation count: 375
H-index: 10
I10-index: 12
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