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Christine Wegler

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes
2017 · Christine Wegler, Fabienne Z. Gaugaz, et al. · Molecular Pharmaceutics · 121
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Global variability analysis of mRNA and protein concentrations across and within human tissues
2019 · Christine Wegler, Magnus Ölander, et al. · NAR Genomics and Bioinformatics · 87
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Intracellular drug bioavailability: a new predictor of system dependent drug disposition
2017 · André Mateus, Andrea Treyer, et al. · Scientific Reports · 80
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Direct Quantification of Cytochromes P450 and Drug Transporters—A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
2018 · Frederik Weiß, Helen S. Hammer, et al. · Drug Metabolism and Disposition · 49
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A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies
2017 · Maria Karlgren, Ivailo Simoff, et al. · Journal of Pharmaceutical Sciences · 45
Short‐ and long‐term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity
2022 · Kine Eide Kvitne, Veronica Krogstad, et al. · British Journal of Clinical Pharmacology · 41
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Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity
2022 · Christine Wegler, Jacek R. Wiśniewski, et al. · Clinical Pharmacology & Therapeutics · 39
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Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions
2016 · Jacek R. Wiśniewski, Christine Wegler, et al. · Analytical Biochemistry · 39
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A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity
2019 · Veronica Krogstad, Alexandra Peric, et al. · Drug Metabolism and Disposition · 36
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Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking
2018 · Jacek R Wiśniewski, Christine Wegler, et al. · Journal of Proteome Research · 36
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Short‐ and long‐term effects of body weight loss following calorie restriction and gastric bypass on CYP3A‐activity – a non‐randomized three‐armed controlled trial
2021 · Kine Eide Kvitne, Ida Robertsen, et al. · Clinical and Translational Science · 34
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Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes
2021 · Christine Wegler, Pär Matsson, et al. · Molecular Pharmaceutics · 30
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range
2022 · Kine Eide Kvitne, Kristine Hole, et al. · European Journal of Clinical Pharmacology · 27
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Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight
2020 · Christine Wegler, Luna Prieto Garcia, et al. · Clinical Pharmacology & Therapeutics · 26
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Hepatocyte size fractionation allows dissection of human liver zonation
2021 · Magnus Ölander, Christine Wegler, et al. · Journal of Cellular Physiology · 22
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Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity
2022 · Kine Eide Kvitne, Anders Åsberg, et al. · Clinical and Translational Science · 18
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Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1
2020 · Christine Wegler, Meryem Gazit, et al. · Journal of Pharmaceutical Sciences · 18
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Simple and rapid quantification of cetirizine, venlafaxine, and O-desmethylvenlafaxine in human breast milk, and metformin in human milk and plasma with UHPLC-MS/MS
2022 · Christine Wegler, Aljona Saleh, et al. · Journal of Chromatography B · 14
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Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project
2023 · Hedvig Nordeng, Christine Wegler, et al. · Basic & Clinical Pharmacology & Toxicology · 12
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Effects of Osteoporosis‐Inducing Drugs on Vitamin D‐Related Gene Transcription and Mineralization in MG ‐63 and Saos‐2 Cells
2016 · Christine Wegler, Kjell Wikvall, et al. · Basic & Clinical Pharmacology & Toxicology · 12
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
2020 · Shno Asad, Christine Wegler, et al. · Journal of Pharmaceutical Sciences · 10
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Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals
2023 · Kine Eide Kvitne, Markus Hovd, et al. · Clinical Pharmacokinetics · 9
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Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance
2023 · Markus Hovd, Ida Robertsen, et al. · Clinical Pharmacokinetics · 8
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Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
2021 · Laura Hellinen, Ali Koskela, et al. · Biomedicine & Pharmacotherapy · 5
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Quantitative Proteomics for Translational Pharmacology and Precision Medicine: State of The Art and Future Outlook
2024 · Bhagwat Prasad, Zubida M. Al-Majdoub, et al. · Drug Metabolism and Disposition · 3
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Works count: 37
Citation count: 824
H-index: 17
I10-index: 21
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